| # | Title | Journal | Year | Citations |
|---|
| 1 | METLIN | Therapeutic Drug Monitoring | 2005 | 1,960 |
| 2 | Population Pharmacokinetic Modeling and Optimal Sampling Strategy for Bayesian Estimation of Amikacin Exposure in Critically Ill Septic Patients | Therapeutic Drug Monitoring | 2010 | 594 |
| 3 | Dried Blood Spot Methods in Therapeutic Drug Monitoring: Methods, Assays, and Pitfalls | Therapeutic Drug Monitoring | 2009 | 447 |
| 4 | Detection Times of Drugs of Abuse in Blood, Urine, and Oral Fluid | Therapeutic Drug Monitoring | 2004 | 408 |
| 5 | Accurate Detection of Outliers and Subpopulations With Pmetrics, a Nonparametric and Parametric Pharmacometric Modeling and Simulation Package for R | Therapeutic Drug Monitoring | 2012 | 406 |
| 6 | Organophosphate Pesticides: Biochemistry and Clinical Toxicology | Therapeutic Drug Monitoring | 2002 | 401 |
| 7 | Opportunities to Optimize Tacrolimus Therapy in Solid Organ Transplantation: Report of the European Consensus Conference | Therapeutic Drug Monitoring | 2009 | 398 |
| 8 | Human Pharmacology of MDMA | Therapeutic Drug Monitoring | 2004 | 377 |
| 9 | Therapeutic Drug Monitoring of Tacrolimus-Personalized Therapy: Second Consensus Report | Therapeutic Drug Monitoring | 2019 | 374 |
| 10 | Mode of Action of Tacrolimus (FK506): Molecular and Cellular Mechanisms | Therapeutic Drug Monitoring | 1995 | 326 |
| 11 | Clinically Important Drug Interactions Potentially Involving Mechanism-based Inhibition of Cytochrome P450 3A4 and the Role of Therapeutic Drug Monitoring | Therapeutic Drug Monitoring | 2007 | 317 |
| 12 | Therapeutic Drug Monitoring of Mycophenolate Mofetil in Transplantation | Therapeutic Drug Monitoring | 2006 | 305 |
| 13 | Comparison of the Effects of Tacrolimus and Cyclosporine on the Pharmacokinetics of Mycophenolic Acid | Therapeutic Drug Monitoring | 2001 | 293 |
| 14 | Therapeutic Drug Monitoring of the Newer Antiepileptic Drugs | Therapeutic Drug Monitoring | 2003 | 291 |
| 15 | Therapeutic Drug Monitoring of Antiepileptic Drugs in Epilepsy: A 2018 Update | Therapeutic Drug Monitoring | 2018 | 286 |
| 16 | Fluvoxamine Inhibition and Carbamazepine Induction of the Metabolism of Clozapine | Therapeutic Drug Monitoring | 1994 | 282 |
| 17 | Rapamune (Sirolimus, Rapamycin): An Overview and Mechanism of Action | Therapeutic Drug Monitoring | 1995 | 273 |
| 18 | Methods for Quantification of Exposure to Cigarette Smoking and Environmental Tobacco Smoke: Focus on Developmental Toxicology | Therapeutic Drug Monitoring | 2009 | 271 |
| 19 | Consensus Document: Therapeutic Monitoring of Tacrolimus (FK-506) | Therapeutic Drug Monitoring | 1995 | 259 |
| 20 | Mechanism of Action of Mycophenolate Mofetil | Therapeutic Drug Monitoring | 1995 | 257 |
| 21 | Acyl Glucuronide Drug Metabolites: Toxicological and Analytical Implications | Therapeutic Drug Monitoring | 2003 | 250 |
| 22 | Clinical Pharmacokinetics of Morphine | Therapeutic Drug Monitoring | 1991 | 249 |
| 23 | Pharmacokinetics and Pharmacodynamics in Clinical Use of Scopolamine | Therapeutic Drug Monitoring | 2005 | 245 |
| 24 | Current Issues in Therapeutic Drug Monitoring of Mycophenolic Acid: Report of a Roundtable Discussion | Therapeutic Drug Monitoring | 2001 | 239 |
| 25 | Role of P-Glycoprotein in Drug Disposition | Therapeutic Drug Monitoring | 2000 | 233 |
| 26 | Lake Louise Consensus Conference on Cyclosporin Monitoring in Organ Transplantation: Report of the Consensus Panel | Therapeutic Drug Monitoring | 1995 | 226 |
| 27 | Use and Abuse of the Benzodiazepines | Therapeutic Drug Monitoring | 1998 | 224 |
| 28 | Impact of Goal-Oriented and Model-Based Clinical Pharmacokinetic Dosing of Aminoglycosides on Clinical Outcome: A Cost-Effectiveness Analysis | Therapeutic Drug Monitoring | 1999 | 214 |
| 29 | Pharmacokinetics of Citalopram in Relation to the Sparteine and the Mephenytoin Oxidation Polymorphisms | Therapeutic Drug Monitoring | 1993 | 209 |
| 30 | Review of Biologic Matrices (Urine, Blood, Hair) as Indicators of Recent or Ongoing Cannabis Use | Therapeutic Drug Monitoring | 2006 | 209 |
| 31 | Toxicokinetics of Amphetamines: Metabolism and Toxicokinetic Data of Designer Drugs, Amphetamine, Methamphetamine, and Their N-Alkyl Derivatives | Therapeutic Drug Monitoring | 2002 | 199 |
| 32 | Cost-Effectiveness of Therapeutic Drug Monitoring | Therapeutic Drug Monitoring | 2005 | 189 |
| 33 | Official International Association for Therapeutic Drug Monitoring and Clinical Toxicology Guideline: Development and Validation of Dried Blood Spot–Based Methods for Therapeutic Drug Monitoring | Therapeutic Drug Monitoring | 2019 | 188 |
| 34 | Genetic Polymorphism of Cytochrome P450s, CYP2C19, and CYP2C9 in a Japanese Population | Therapeutic Drug Monitoring | 1998 | 188 |
| 35 | Hair Analysis for Drug Detection | Therapeutic Drug Monitoring | 2006 | 185 |
| 36 | Pharmacogenetics of Thiopurine S-Methyltransferase and Thiopurine Therapy | Therapeutic Drug Monitoring | 2004 | 183 |
| 37 | Slow Omeprazole Metabolizers Are Also Poor S-Mephenytoin Hydroxylators | Therapeutic Drug Monitoring | 1990 | 176 |
| 38 | Haloperidol Disposition Is Dependent on Debrisoquine Hydroxylation Phenotype | Therapeutic Drug Monitoring | 1992 | 174 |
| 39 | Infliximab Pharmacokinetics in Inflammatory Bowel Disease Patients | Therapeutic Drug Monitoring | 2008 | 172 |
| 40 | Therapeutic Drug Monitoring of Antiepileptic Drugs by Use of Saliva | Therapeutic Drug Monitoring | 2013 | 172 |
| 41 | Evidence That Tacrolimus Augments the Bioavailability of Mycophenolate Mofetil Through the Inhibition of Mycophenolic Acid Glucuronidation | Therapeutic Drug Monitoring | 1999 | 171 |
| 42 | Pharmacokinetic and Metabolic Investigations of Mycophenolic Acid in Pediatric Patients After Renal Transplantation: Implications for Therapeutic Drug Monitoring | Therapeutic Drug Monitoring | 2000 | 171 |
| 43 | Clinical Aspects of the MDR1 (ABCB1) Gene Polymorphism | Therapeutic Drug Monitoring | 2004 | 170 |
| 44 | Itraconazole Decreases Renal Clearance of Digoxin | Therapeutic Drug Monitoring | 1997 | 169 |
| 45 | Pharmacologic Analysis of Drug Receptor Interaction | Therapeutic Drug Monitoring | 1988 | 166 |
| 46 | Population Pharmacokinetics of Metformin in Late Pregnancy | Therapeutic Drug Monitoring | 2006 | 165 |
| 47 | Population Pharmacokinetic and Pharmacodynamic Analysis of Ribavirin in Patients With Chronic Hepatitis C | Therapeutic Drug Monitoring | 2000 | 163 |
| 48 | Biomarkers of Drug-Induced Kidney Toxicity | Therapeutic Drug Monitoring | 2019 | 156 |
| 49 | Randomized, Double-Blind, Placebo-Controlled Study About the Effects of Cannabidiol (CBD) on the Pharmacokinetics of ??9-Tetrahydrocannabinol (THC) After Oral Application of THC Verses Standardized Cannabis Extract | Therapeutic Drug Monitoring | 2005 | 152 |
| 50 | Extremely Rapid Hydroxylation of Debrisoquine | Therapeutic Drug Monitoring | 1985 | 151 |
