| # | Title | Journal | Year | Citations |
|---|
| 1 | Further improvements in the plaque technique for detecting single antibody-forming cells | Immunology | 1968 | 1,924 |
| 2 | The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulations in the rat recognized by monoclonal antibodies ED1, ED2 and ED3 | Immunology | 1985 | 1,344 |
| 3 | Quantitative assay of the lytic action of immune lymphoid cells on 51-Cr-labelled allogeneic target cells in vitro; inhibition by isoantibody and by drugs | Immunology | 1968 | 1,173 |
| 4 | Inflammation in neurodegenerative diseases | Immunology | 2010 | 1,104 |
| 5 | Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4 | Immunology | 2004 | 1,057 |
| 6 | Human dendritic cell subsets: an update | Immunology | 2018 | 866 |
| 7 | Cancer immunoediting from immune surveillance to immune escape | Immunology | 2007 | 863 |
| 8 | The immune response to Prevotella bacteria in chronic inflammatory disease | Immunology | 2017 | 789 |
| 9 | Interleukin‐17 and its target genes: mechanisms of interleukin‐17 function in disease | Immunology | 2010 | 738 |
| 10 | CD56bright natural killer (NK) cells: an important NK cell subset | Immunology | 2009 | 735 |
| 11 | Immunosenescence: emerging challenges for an ageing population | Immunology | 2007 | 711 |
| 12 | The intriguing biology of the tumour necrosis factor/tumour necrosis factor receptor superfamily: players, rules and the games | Immunology | 2005 | 697 |
| 13 | Normal human pregnancy is associated with an elevation in the immune suppressive CD25+ CD4+ regulatory T-cell subset | Immunology | 2004 | 679 |
| 14 | Interleukin‐17 in host defence against bacterial, mycobacterial and fungal pathogens | Immunology | 2009 | 672 |
| 15 | Cell interactions in the induction of tolerance: the role of thymic lymphocytes | Immunology | 1970 | 665 |
| 16 | The immunosuppressive tumour network: myeloid‐derived suppressor cells, regulatory T cells and natural killer T cells | Immunology | 2013 | 643 |
| 17 | Infectious immunological tolerance | Immunology | 1971 | 642 |
| 18 | Inflammation in CNS neurodegenerative diseases | Immunology | 2018 | 640 |
| 19 | Improved methods for predicting peptide binding affinity to MHC class II molecules | Immunology | 2018 | 629 |
| 20 | Effects of the new anti-lymphocytic peptide cyclosporin A in animals | Immunology | 1977 | 617 |
| 21 | Mechanisms of immune suppression by interleukin-10 and transforming growth factor-beta: the role of T regulatory cells | Immunology | 2006 | 594 |
| 22 | Immunological decision‐making: how does the immune system decide to mount a helper T‐cell response? | Immunology | 2008 | 584 |
| 23 | Implications of macrophage polarization in autoimmunity | Immunology | 2018 | 572 |
| 24 | T‐cell exhaustion: characteristics, causes and conversion | Immunology | 2010 | 506 |
| 25 | Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MRC OX-41 and MRC OX-42, the latter recognizing complement receptor type 3 | Immunology | 1986 | 501 |
| 26 | Human blood contains two subsets of dendritic cells, one immunologically mature and the other immature | Immunology | 1994 | 475 |
| 27 | Intestinal colonization resistance | Immunology | 2013 | 466 |
| 28 | Human dendritic cell subsets | Immunology | 2013 | 448 |
| 29 | Fibrosis in heart disease: understanding the role of transforming growth factor-beta1 in cardiomyopathy, valvular disease and arrhythmia | Immunology | 2006 | 447 |
| 30 | Nitric oxide and bone | Immunology | 2001 | 444 |
| 31 | Functional subsets of human helper-inducer cells defined by a new monoclonal antibody, UCHL1 | Immunology | 1986 | 439 |
| 32 | Two distinct populations of peripheral lymphocytes in mice distinguishable by immunofluorescence | Immunology | 1970 | 439 |
| 33 | Inflammation in neurodegenerative diseases – an update | Immunology | 2014 | 434 |
| 34 | Nitric oxide in inflammatory bowel disease: a universal messenger in an unsolved puzzle | Immunology | 2004 | 432 |
| 35 | Rat macrophage lysosomal membrane antigen recognized by monoclonal antibody ED1 | Immunology | 1994 | 423 |
| 36 | Properties and functions of adipose tissue macrophages in obesity | Immunology | 2018 | 421 |
| 37 | Human protectin (CD59), an 18,000-20,000 MW complement lysis restricting factor, inhibits C5b-8 catalysed insertion of C9 into lipid bilayers | Immunology | 1990 | 419 |
| 38 | Vitamin D3, gamma interferon, and control of proliferation of Mycobacterium tuberculosis by human monocytes | Immunology | 1986 | 418 |
| 39 | Mucosal immunology | Immunology | 1980 | 417 |
| 40 | IgG4 breaking the rules | Immunology | 2002 | 409 |
| 41 | Strong adjuvant properties of cholera toxin on gut mucosal immune responses to orally presented antigens | Immunology | 1986 | 382 |
| 42 | CD8+ CD28− and CD8+ CD57+ T cells and their role in health and disease | Immunology | 2011 | 378 |
| 43 | Tryptophan deprivation sensitizes activated T cells to apoptosis prior to cell division | Immunology | 2002 | 375 |
| 44 | E-selectin and intercellular adhesion molecule-1 are released by activated human endothelial cells in vitro | Immunology | 1992 | 375 |
| 45 | A cathelicidin family of human antibacterial peptide LL-37 induces mast cell chemotaxis | Immunology | 2002 | 374 |
| 46 | Enhanced and prolonged cross-presentation following endosomal escape of exogenous antigens encapsulated in biodegradable nanoparticles | Immunology | 2006 | 373 |
| 47 | Neutrophil mobilization and clearance in the bone marrow | Immunology | 2008 | 370 |
| 48 | The increased prevalence of allergy and the hygiene hypothesis: missing immune deviation, reduced immune suppression, or both? | Immunology | 2004 | 365 |
| 49 | Neuropeptides activate human mast cell degranulation and chemokine production | Immunology | 2008 | 364 |
| 50 | Specific inhibition of antibody production. II. Paralysis induced in adult mice by small quantities of protein antigen | Immunology | 1962 | 358 |
