| # | Title | Journal | Year | Citations |
|---|
| 1 | Inflammation and Cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation | American Journal of Physiology - Renal Physiology | 2004 | 1,063 |
| 2 | The adherent gastrointestinal mucus gel layer: thickness and physical state in vivo | American Journal of Physiology - Renal Physiology | 2001 | 796 |
| 3 | Propensity to high-fat diet-induced obesity in rats is associated with changes in the gut microbiota and gut inflammation | American Journal of Physiology - Renal Physiology | 2010 | 747 |
| 4 | TNF-α-induced increase in intestinal epithelial tight junction permeability requires NF-κB activation | American Journal of Physiology - Renal Physiology | 2004 | 736 |
| 5 | Molecular mechanisms of hepatic ischemia-reperfusion injury and preconditioning | American Journal of Physiology - Renal Physiology | 2003 | 734 |
| 6 | Increased intestinal permeability in obese mice: new evidence in the pathogenesis of nonalcoholic steatohepatitis | American Journal of Physiology - Renal Physiology | 2007 | 702 |
| 7 | Lipid Metabolism and Liver Inflammation. II. Fatty liver disease and fatty acid oxidation | American Journal of Physiology - Renal Physiology | 2006 | 689 |
| 8 | Colonic microbiome is altered in alcoholism | American Journal of Physiology - Renal Physiology | 2012 | 600 |
| 9 | Mechanisms of Liver Injury. I. TNF-α-induced liver injury: role of IKK, JNK, and ROS pathways | American Journal of Physiology - Renal Physiology | 2006 | 597 |
| 10 | Probiotic bacteria and intestinal epithelial barrier function | American Journal of Physiology - Renal Physiology | 2010 | 567 |
| 11 | Novel role of the vitamin D receptor in maintaining the integrity of the intestinal mucosal barrier | American Journal of Physiology - Renal Physiology | 2008 | 540 |
| 12 | IL-22 is increased in active Crohn’s disease and promotes proinflammatory gene expression and intestinal epithelial cell migration | American Journal of Physiology - Renal Physiology | 2006 | 487 |
| 13 | Critical role of gut microbiota in the production of biologically active, free catecholamines in the gut lumen of mice | American Journal of Physiology - Renal Physiology | 2012 | 482 |
| 14 | Regulation of human epithelial tight junction proteins by Lactobacillus plantarum in vivo and protective effects on the epithelial barrier | American Journal of Physiology - Renal Physiology | 2010 | 481 |
| 15 | Secreted bioactive factors fromBifidobacterium infantisenhance epithelial cell barrier function | American Journal of Physiology - Renal Physiology | 2008 | 480 |
| 16 | A novel human organic anion transporting polypeptide localized to the basolateral hepatocyte membrane | American Journal of Physiology - Renal Physiology | 2000 | 479 |
| 17 | Probiotics inhibit enteropathogenicE. coliadherence in vitro by inducing intestinal mucin gene expression | American Journal of Physiology - Renal Physiology | 1999 | 473 |
| 18 | Increased stiffness of the rat liver precedes matrix deposition: implications for fibrosis | American Journal of Physiology - Renal Physiology | 2007 | 472 |
| 19 | Colonic mucosal microbiome differs from stool microbiome in cirrhosis and hepatic encephalopathy and is linked to cognition and inflammation | American Journal of Physiology - Renal Physiology | 2012 | 462 |
| 20 | Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis | American Journal of Physiology - Renal Physiology | 2005 | 461 |
| 21 | Acute colitis induced by dextran sulfate sodium progresses to chronicity in C57BL/6 but not in BALB/c mice: correlation between symptoms and inflammation | American Journal of Physiology - Renal Physiology | 2005 | 455 |
| 22 | Linkage of gut microbiome with cognition in hepatic encephalopathy | American Journal of Physiology - Renal Physiology | 2012 | 448 |
| 23 | Tight junctions and the molecular basis for regulation of paracellular permeability | American Journal of Physiology - Renal Physiology | 1995 | 444 |
| 24 | IV. Regulation of tight junctions by extracellular stimuli: nutrients, cytokines, and immune cells | American Journal of Physiology - Renal Physiology | 2000 | 418 |
| 25 | Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2 | American Journal of Physiology - Renal Physiology | 2012 | 417 |
| 26 | Homeostasis of the gut barrier and potential biomarkers | American Journal of Physiology - Renal Physiology | 2017 | 408 |
| 27 | Gut-derived short-chain fatty acids are vividly assimilated into host carbohydrates and lipids | American Journal of Physiology - Renal Physiology | 2013 | 401 |
| 28 | Lipopolysaccharides in liver injury: molecular mechanisms of Kupffer cell activation | American Journal of Physiology - Renal Physiology | 2002 | 400 |
| 29 | Mechanisms of Liver Injury. II. Mechanisms of neutrophil-induced liver cell injury during hepatic ischemia-reperfusion and other acute inflammatory conditions | American Journal of Physiology - Renal Physiology | 2006 | 398 |
| 30 | Effect of meal viscosity and nutrients on satiety, intragastric dilution, and emptying assessed by MRI | American Journal of Physiology - Renal Physiology | 2001 | 394 |
| 31 | Probiotic mixture VSL#3 protects the epithelial barrier by maintaining tight junction protein expression and preventing apoptosis in a murine model of colitis | American Journal of Physiology - Renal Physiology | 2009 | 392 |
| 32 | The VSL#3 probiotic formula induces mucin gene expression and secretion in colonic epithelial cells | American Journal of Physiology - Renal Physiology | 2007 | 389 |
| 33 | Neonatal maternal separation alters stress-induced responses to viscerosomatic nociceptive stimuli in rat | American Journal of Physiology - Renal Physiology | 2002 | 384 |
| 34 | Fibrogenesis II. Metalloproteinases and their inhibitors in liver fibrosis | American Journal of Physiology - Renal Physiology | 2000 | 381 |
| 35 | Severe NAFLD with hepatic necroinflammatory changes in mice fed trans fats and a high-fructose corn syrup equivalent | American Journal of Physiology - Renal Physiology | 2008 | 374 |
| 36 | II. Stress and intestinal barrier function | American Journal of Physiology - Renal Physiology | 2001 | 372 |
| 37 | Mechanism of TNF-α modulation of Caco-2 intestinal epithelial tight junction barrier: role of myosin light-chain kinase protein expression | American Journal of Physiology - Renal Physiology | 2005 | 372 |
| 38 | Early weaning stress impairs development of mucosal barrier function in the porcine intestine | American Journal of Physiology - Renal Physiology | 2010 | 368 |
| 39 | V. Stress and irritable bowel syndrome | American Journal of Physiology - Renal Physiology | 2001 | 362 |
| 40 | T cell transfer model of chronic colitis: concepts, considerations, and tricks of the trade | American Journal of Physiology - Renal Physiology | 2009 | 362 |
| 41 | Methane, a gas produced by enteric bacteria, slows intestinal transit and augments small intestinal contractile activity | American Journal of Physiology - Renal Physiology | 2006 | 361 |
| 42 | 1α,25-Dihydroxyvitamin D3 upregulates FGF23 gene expression in bone: the final link in a renal-gastrointestinal-skeletal axis that controls phosphate transport | American Journal of Physiology - Renal Physiology | 2005 | 359 |
| 43 | Fast food diet mouse: novel small animal model of NASH with ballooning, progressive fibrosis, and high physiological fidelity to the human condition | American Journal of Physiology - Renal Physiology | 2011 | 357 |
| 44 | Gene expression in human NAFLD | American Journal of Physiology - Renal Physiology | 2008 | 356 |
| 45 | Functional modulation of enterocytes by gram-positive and gram-negative microorganisms | American Journal of Physiology - Renal Physiology | 2004 | 348 |
| 46 | Microbiota transplantation restores normal fecal bile acid composition in recurrentClostridium difficileinfection | American Journal of Physiology - Renal Physiology | 2014 | 341 |
| 47 | Molecular Physiology and Pathophysiology of Tight Junctions I. Tight junction structure and function: lessons from mutant animals and proteins | American Journal of Physiology - Renal Physiology | 2000 | 340 |
| 48 | Saturated fat stimulates obesity and hepatic steatosis and affects gut microbiota composition by an enhanced overflow of dietary fat to the distal intestine | American Journal of Physiology - Renal Physiology | 2012 | 330 |
| 49 | Resveratrol alleviates alcoholic fatty liver in mice | American Journal of Physiology - Renal Physiology | 2008 | 324 |
| 50 | Probiotics ameliorate the hydrogen peroxide-induced epithelial barrier disruption by a PKC- and MAP kinase-dependent mechanism | American Journal of Physiology - Renal Physiology | 2008 | 320 |
