9.8(top 2%)
impact factor
6.0K(top 5%)
papers
389.5K(top 1%)
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283(top 1%)
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9.9(top 2%)
impact factor
7.2K
all documents
404.0K
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401(top 1%)
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Top Articles

#TitleJournalYearCitations
1Amyloid deposition as the central event in the aetiology of Alzheimer's diseaseTrends in Pharmacological Sciences19912,091
2Drugs of abuse: anatomy, pharmacology and function of reward pathwaysTrends in Pharmacological Sciences19921,943
3Excitatory amino acid neurotoxicity and neurodegenerative diseaseTrends in Pharmacological Sciences19901,678
4Assessing antidepressant activity in rodents: recent developments and future needsTrends in Pharmacological Sciences20021,373
5Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapyTrends in Pharmacological Sciences20121,271
6Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular functionTrends in Pharmacological Sciences20061,237
7Liposomes and nanoparticles: nanosized vehicles for drug delivery in cancerTrends in Pharmacological Sciences20091,097
8Current advances and trends in the treatment of depressionTrends in Pharmacological Sciences19941,040
9The release and uptake of excitatory amino acidsTrends in Pharmacological Sciences1990989
10Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targetsTrends in Pharmacological Sciences2009940
11G-protein-coupled receptors and signaling networks: emerging paradigmsTrends in Pharmacological Sciences2001933
12Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinasesTrends in Pharmacological Sciences1989898
13Molecular biology of dopamine receptorsTrends in Pharmacological Sciences1992890
14FGF and VEGF function in angiogenesis: signalling pathways, biological responses and therapeutic inhibitionTrends in Pharmacological Sciences2001859
15Structure-activity relationships in the development of excitatory ammo acid receptor agonists and competitive antagonistsTrends in Pharmacological Sciences1990846
16Excitatory amino acid receptors and synaptic plasticityTrends in Pharmacological Sciences1990835
17Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitorsTrends in Pharmacological Sciences1990830
18Zebrafish as an emerging model for studying complex brain disordersTrends in Pharmacological Sciences2014827
19Cell-Penetrating Peptides: From Basic Research to ClinicsTrends in Pharmacological Sciences2017812
20Cell-penetrating peptidesTrends in Pharmacological Sciences2000809
21Dopamine receptor pharmacologyTrends in Pharmacological Sciences1994807
22FDA-approved small-molecule kinase inhibitorsTrends in Pharmacological Sciences2015794
23Role of Ca2+ in toxic cell killingTrends in Pharmacological Sciences1989790
24Brain nicotinic acetylcholine receptors: native subtypes and their relevanceTrends in Pharmacological Sciences2006782
25Targeting Free Radicals in Oxidative Stress-Related Human DiseasesTrends in Pharmacological Sciences2017781
26Sickness behavior as a new target for drug developmentTrends in Pharmacological Sciences1992766
27Adipokines in health and diseaseTrends in Pharmacological Sciences2015766
28Neonicotinoids: insecticides acting on insect nicotinic acetylcholine receptorsTrends in Pharmacological Sciences2001760
29Constitutive activity of receptors coupled to guanine nucleotide regulatory proteinsTrends in Pharmacological Sciences1993756
30The efficiency of multi-target drugs: the network approach might help drug designTrends in Pharmacological Sciences2005745
31EDHF: bringing the concepts togetherTrends in Pharmacological Sciences2002731
32Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herbTrends in Pharmacological Sciences2009717
33Rho–Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cellsTrends in Pharmacological Sciences2001693
34Anti-inflammatory actions of steroids: molecular mechanismsTrends in Pharmacological Sciences1993687
35Metabotropic glutamate receptors in brain function and pathologyTrends in Pharmacological Sciences1993683
36Neurosteroids and GABAA receptor functionTrends in Pharmacological Sciences1995680
37Non-genomic and genomic effects of steroids on neural activityTrends in Pharmacological Sciences1991674
38Role of poly(ADP-ribose) synthetase in inflammation and ischaemia–reperfusionTrends in Pharmacological Sciences1998666
39Conformational complexity of G-protein-coupled receptorsTrends in Pharmacological Sciences2007646
40PPARs: therapeutic targets for metabolic diseaseTrends in Pharmacological Sciences2005632
41β-arrestin-mediated receptor trafficking and signal transductionTrends in Pharmacological Sciences2011628
42The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseasesTrends in Pharmacological Sciences2003627
43Glucocorticoid receptor signaling in health and diseaseTrends in Pharmacological Sciences2013626
44Molecular diversity of voltage-dependent Ca2+ channelsTrends in Pharmacological Sciences1991620
45The role of stress in drug self-administrationTrends in Pharmacological Sciences1998620
46Agonist-receptor efficacy II: agonist trafficking of receptor signalsTrends in Pharmacological Sciences1995619
47Mechanisms of Hedgehog pathway activation in cancer and implications for therapyTrends in Pharmacological Sciences2009615
48How does adenosine inhibit transmitter release?Trends in Pharmacological Sciences1988606
49Islet-activating protein, pertussis toxin: a probe for functions of the inhibitory guanine nucleotide regulatory component of adenylate cyclaseTrends in Pharmacological Sciences1984603
50Cyclooxygenase 2: a molecular target for cancer prevention and treatmentTrends in Pharmacological Sciences2003602