| # | Title | Journal | Year | Citations |
|---|
| 1 | Glucose clamp technique: a method for quantifying insulin secretion and resistance. | American Journal of Physiology - Endocrinology and Metabolism | 1979 | 4,022 |
| 2 | Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance | American Journal of Physiology - Endocrinology and Metabolism | 2001 | 1,494 |
| 3 | Unexpected evidence for active brown adipose tissue in adult humans | American Journal of Physiology - Endocrinology and Metabolism | 2007 | 1,492 |
| 4 | Magnetic resonance spectroscopy to measure hepatic triglyceride content: prevalence of hepatic steatosis in the general population | American Journal of Physiology - Endocrinology and Metabolism | 2005 | 1,323 |
| 5 | Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves. | American Journal of Physiology - Endocrinology and Metabolism | 1978 | 1,196 |
| 6 | Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage | American Journal of Physiology - Endocrinology and Metabolism | 2008 | 1,114 |
| 7 | Quantitative estimation of insulin sensitivity. | American Journal of Physiology - Endocrinology and Metabolism | 1979 | 1,063 |
| 8 | Regulation of endogenous fat and carbohydrate metabolism in relation to exercise intensity and duration | American Journal of Physiology - Endocrinology and Metabolism | 1993 | 956 |
| 9 | Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE | American Journal of Physiology - Endocrinology and Metabolism | 2001 | 890 |
| 10 | Lipopolysaccharide activates an innate immune system response in human adipose tissue in obesity and type 2 diabetes | American Journal of Physiology - Endocrinology and Metabolism | 2007 | 842 |
| 11 | IL-6 enhances plasma IL-1ra, IL-10, and cortisol in humans | American Journal of Physiology - Endocrinology and Metabolism | 2003 | 837 |
| 12 | Fetal origins of hyperphagia, obesity, and hypertension and postnatal amplification by hypercaloric nutrition | American Journal of Physiology - Endocrinology and Metabolism | 2000 | 824 |
| 13 | Testosterone dose-response relationships in healthy young men | American Journal of Physiology - Endocrinology and Metabolism | 2001 | 767 |
| 14 | IRS proteins and the common path to diabetes | American Journal of Physiology - Endocrinology and Metabolism | 2002 | 757 |
| 15 | Glucose transporters in the 21st Century | American Journal of Physiology - Endocrinology and Metabolism | 2010 | 746 |
| 16 | Skeletal muscle atrophy and the E3 ubiquitin ligases MuRF1 and MAFbx/atrogin-1 | American Journal of Physiology - Endocrinology and Metabolism | 2014 | 735 |
| 17 | A high proportion of leucine is required for optimal stimulation of the rate of muscle protein synthesis by essential amino acids in the elderly | American Journal of Physiology - Endocrinology and Metabolism | 2006 | 734 |
| 18 | AMPK and SIRT1: a long-standing partnership? | American Journal of Physiology - Endocrinology and Metabolism | 2010 | 717 |
| 19 | Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue ofob/oband dietary obese mice | American Journal of Physiology - Endocrinology and Metabolism | 2007 | 712 |
| 20 | Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action | American Journal of Physiology - Endocrinology and Metabolism | 2006 | 709 |
| 21 | The adipocyte: a model for integration of endocrine and metabolic signaling in energy metabolism regulation | American Journal of Physiology - Endocrinology and Metabolism | 2001 | 706 |
| 22 | Insulin-sensitive obesity | American Journal of Physiology - Endocrinology and Metabolism | 2010 | 670 |
| 23 | Mixed muscle protein synthesis and breakdown after resistance exercise in humans | American Journal of Physiology - Endocrinology and Metabolism | 1997 | 661 |
| 24 | Lipoprotein lipase: from gene to obesity | American Journal of Physiology - Endocrinology and Metabolism | 2009 | 660 |
| 25 | Glucagon and regulation of glucose metabolism | American Journal of Physiology - Endocrinology and Metabolism | 2003 | 651 |
| 26 | AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle | American Journal of Physiology - Endocrinology and Metabolism | 1997 | 649 |
| 27 | Regulation of adiponectin by adipose tissue-derived cytokines: in vivo and in vitro investigations in humans | American Journal of Physiology - Endocrinology and Metabolism | 2003 | 638 |
| 28 | Evaluating the glucose tolerance test in mice | American Journal of Physiology - Endocrinology and Metabolism | 2008 | 635 |
| 29 | Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss | American Journal of Physiology - Endocrinology and Metabolism | 1999 | 629 |
| 30 | The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation | American Journal of Physiology - Endocrinology and Metabolism | 2010 | 614 |
| 31 | COVID-19 pandemic, coronaviruses, and diabetes mellitus | American Journal of Physiology - Endocrinology and Metabolism | 2020 | 596 |
| 32 | Intestinal lipid absorption | American Journal of Physiology - Endocrinology and Metabolism | 2009 | 595 |
| 33 | AMP-activated protein kinase, a metabolic master switch: possible roles in Type 2 diabetes | American Journal of Physiology - Endocrinology and Metabolism | 1999 | 590 |
| 34 | Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells | American Journal of Physiology - Endocrinology and Metabolism | 2006 | 588 |
| 35 | Algorithms for the study of episodic hormone secretion | American Journal of Physiology - Endocrinology and Metabolism | 1982 | 587 |
| 36 | Effects of glucagon-like peptide-1 on endothelial function in type 2 diabetes patients with stable coronary artery disease | American Journal of Physiology - Endocrinology and Metabolism | 2004 | 583 |
| 37 | The Randle cycle revisited: a new head for an old hat | American Journal of Physiology - Endocrinology and Metabolism | 2009 | 578 |
| 38 | Biochemical and physiological function of stearoyl-CoA desaturase | American Journal of Physiology - Endocrinology and Metabolism | 2009 | 551 |
| 39 | Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans | American Journal of Physiology - Endocrinology and Metabolism | 2004 | 518 |
| 40 | IGF-I stimulates muscle growth by suppressing protein breakdown and expression of atrophy-related ubiquitin ligases, atrogin-1 and MuRF1 | American Journal of Physiology - Endocrinology and Metabolism | 2004 | 516 |
| 41 | Cluster analysis: a simple, versatile, and robust algorithm for endocrine pulse detection | American Journal of Physiology - Endocrinology and Metabolism | 1986 | 505 |
| 42 | Lipid oxidation is reduced in obese human skeletal muscle | American Journal of Physiology - Endocrinology and Metabolism | 2000 | 494 |
| 43 | Insulin-like growth factor (IGF)-binding proteins: interactions with IGFs and intrinsic bioactivities | American Journal of Physiology - Endocrinology and Metabolism | 2000 | 491 |
| 44 | Cardiac hypertrophy in vitamin D receptor knockout mice: role of the systemic and cardiac renin-angiotensin systems | American Journal of Physiology - Endocrinology and Metabolism | 2005 | 489 |
| 45 | Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet | American Journal of Physiology - Endocrinology and Metabolism | 2009 | 487 |
| 46 | Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise | American Journal of Physiology - Endocrinology and Metabolism | 1996 | 472 |
| 47 | An abundant supply of amino acids enhances the metabolic effect of exercise on muscle protein | American Journal of Physiology - Endocrinology and Metabolism | 1997 | 469 |
| 48 | Recruited vs. nonrecruited molecular signatures of brown, “brite,” and white adipose tissues | American Journal of Physiology - Endocrinology and Metabolism | 2012 | 467 |
| 49 | Leptin in human physiology and pathophysiology | American Journal of Physiology - Endocrinology and Metabolism | 2011 | 458 |
| 50 | Transcriptional regulation of gene expression in human skeletal muscle during recovery from exercise | American Journal of Physiology - Endocrinology and Metabolism | 2000 | 457 |
