| # | Title | Journal | Year | Citations |
|---|
| 1 | Interleukin-6 and chronic inflammation | Arthritis Research and Therapy | 2006 | 1,044 |
| 2 | Mesenchymal stromal cells. Biology of adult mesenchymal stem cells: regulation of niche, self-renewal and differentiation | Arthritis Research and Therapy | 2007 | 801 |
| 3 | Articular cartilage and changes in Arthritis: Cell biology of osteoarthritis | Arthritis Research and Therapy | 2001 | 734 |
| 4 | Epidemiological studies in incidence, prevalence, mortality, and comorbidity of the rheumatic diseases | Arthritis Research and Therapy | 2009 | 682 |
| 5 | Biology of RANK, RANKL, and osteoprotegerin | Arthritis Research and Therapy | 2007 | 674 |
| 6 | A pilot study of IL-1 inhibition by anakinra in acute gout | Arthritis Research and Therapy | 2007 | 643 |
| 7 | Mesenchymal precursor cells in the blood of normal individuals | Arthritis Research and Therapy | 2000 | 625 |
| 8 | Synovitis in osteoarthritis: current understanding with therapeutic implications | Arthritis Research and Therapy | 2017 | 615 |
| 9 | Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients | Arthritis Research and Therapy | 2008 | 600 |
| 10 | Cartilage homeostasis in health and rheumatic diseases | Arthritis Research and Therapy | 2009 | 588 |
| 11 | Subchondral bone in osteoarthritis: insight into risk factors and microstructural changes | Arthritis Research and Therapy | 2013 | 563 |
| 12 | The Revised Fibromyalgia Impact Questionnaire (FIQR): validation and psychometric properties | Arthritis Research and Therapy | 2009 | 514 |
| 13 | Catabolic cytokine expression in degenerate and herniated human intervertebral discs: IL-1β and TNFα expression profile | Arthritis Research and Therapy | 2007 | 502 |
| 14 | Anti-inflammatory and immunosuppressive drugs and reproduction | Arthritis Research and Therapy | 2006 | 469 |
| 15 | Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin | Arthritis Research and Therapy | 2005 | 425 |
| 16 | The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial | Arthritis Research and Therapy | 2010 | 420 |
| 17 | The role of synovial macrophages and macrophage-produced cytokines in driving aggrecanases, matrix metalloproteinases, and other destructive and inflammatory responses in osteoarthritis | Arthritis Research and Therapy | 2006 | 414 |
| 18 | Aseptic loosening of total joint replacements: mechanisms underlying osteolysis and potential therapies | Arthritis Research and Therapy | 2007 | 414 |
| 19 | Promise and pitfalls of the Immunochip | Arthritis Research and Therapy | 2010 | 412 |
| 20 | Pathogenesis of tendinopathies: inflammation or degeneration? | Arthritis Research and Therapy | 2009 | 410 |
| 21 | Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis | Arthritis Research and Therapy | 2010 | 406 |
| 22 | Antibodies to citrullinated proteins and differences in clinical progression of rheumatoid arthritis | Arthritis Research and Therapy | 2005 | 400 |
| 23 | Interleukin-6: discovery of a pleiotropic cytokine | Arthritis Research and Therapy | 2006 | 396 |
| 24 | Cardiovascular disease in patients with rheumatoid arthritis: results from the QUEST-RA study | Arthritis Research and Therapy | 2008 | 387 |
| 25 | MMP13 is a critical target gene during the progression of osteoarthritis | Arthritis Research and Therapy | 2013 | 385 |
| 26 | Use of NSAIDs in treating patients with arthritis | Arthritis Research and Therapy | 2013 | 373 |
| 27 | Incidence of malignancy in adult patients with rheumatoid arthritis: a meta-analysis | Arthritis Research and Therapy | 2015 | 368 |
| 28 | Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration | Arthritis Research and Therapy | 2007 | 365 |
| 29 | Assessment of radiographic progression in the spines of patients with ankylosing spondylitis treated with adalimumab for up to 2 years | Arthritis Research and Therapy | 2009 | 357 |
| 30 | A meta-analysis of the incidence of malignancy in adult patients with rheumatoid arthritis | Arthritis Research and Therapy | 2008 | 349 |
| 31 | Systemic lupus erythematosus induced by anti-tumour necrosis factor alpha therapy: a French national survey | Arthritis Research and Therapy | 2005 | 336 |
| 32 | Prevalence of opioid adverse events in chronic non-malignant pain: systematic review of randomised trials of oral opioids | Arthritis Research and Therapy | 2005 | 321 |
| 33 | Developments in the scientific understanding of osteoarthritis | Arthritis Research and Therapy | 2009 | 318 |
| 34 | Efficacy of different types of aerobic exercise in fibromyalgia syndrome: a systematic review and meta-analysis of randomised controlled trials | Arthritis Research and Therapy | 2010 | 317 |
| 35 | Fibroblast-like synoviocyte metabolism in the pathogenesis of rheumatoid arthritis | Arthritis Research and Therapy | 2017 | 311 |
| 36 | Identification of citrullinated alpha-enolase as a candidate autoantigen in rheumatoid arthritis | Arthritis Research and Therapy | 2005 | 304 |
| 37 | Rheumatic Diseases in China | Arthritis Research and Therapy | 2008 | 302 |
| 38 | Gout. Epidemiology of gout | Arthritis Research and Therapy | 2010 | 302 |
| 39 | Environmental risk factors differ between rheumatoid arthritis with and without auto-antibodies against cyclic citrullinated peptides | Arthritis Research and Therapy | 2006 | 299 |
| 40 | Rheumatoid arthritis associated autoantibodies in patients with synovitis of recent onset | Arthritis Research and Therapy | 2000 | 298 |
| 41 | Anti-inflammatory and antiarthritic effects of piperine in human interleukin 1β-stimulated fibroblast-like synoviocytes and in rat arthritis models | Arthritis Research and Therapy | 2009 | 297 |
| 42 | Increased expression of FcgammaRI/CD64 on circulating monocytes parallels ongoing inflammation and nephritis in lupus | Arthritis Research and Therapy | 2009 | 297 |
| 43 | Control of hyperuricemia in subjects with refractory gout, and induction of antibody against poly(ethylene glycol) (PEG), in a phase I trial of subcutaneous PEGylated urate oxidase | Arthritis Research and Therapy | 2006 | 293 |
| 44 | The role of the central nervous system in the generation and maintenance of chronic pain in rheumatoid arthritis, osteoarthritis and fibromyalgia | Arthritis Research and Therapy | 2011 | 293 |
| 45 | Synovial phenotypes in rheumatoid arthritis correlate with response to biologic therapeutics | Arthritis Research and Therapy | 2014 | 292 |
| 46 | Enhanced neutrophil extracellular trap generation in rheumatoid arthritis: analysis of underlying signal transduction pathways and potential diagnostic utility | Arthritis Research and Therapy | 2014 | 290 |
| 47 | Predictors of major infections in systemic lupus erythematosus | Arthritis Research and Therapy | 2009 | 288 |
| 48 | Nonsteroidal anti-inflammatory drugs and upper and lower gastrointestinal mucosal damage | Arthritis Research and Therapy | 2013 | 284 |
| 49 | Hypertrophic differentiation of chondrocytes in osteoarthritis: the developmental aspect of degenerative joint disorders | Arthritis Research and Therapy | 2010 | 280 |
| 50 | Integrated safety in tocilizumab clinical trials | Arthritis Research and Therapy | 2011 | 278 |
