# | Title | Journal | Year | Citations |
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1 | Evaluation of the probe 2',7'-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress | Chemical Research in Toxicology | 1992 | 2,374 |
2 | Role of Quinones in Toxicology | Chemical Research in Toxicology | 2000 | 1,456 |
3 | Common and Uncommon Cytochrome P450 Reactions Related to Metabolism and Chemical Toxicity | Chemical Research in Toxicology | 2001 | 1,456 |
4 | Peroxynitrite, a cloaked oxidant formed by nitric oxide and superoxide | Chemical Research in Toxicology | 1992 | 1,342 |
5 | Mechanistic Applicability Domain Classification of a Local Lymph Node Assay Dataset for Skin Sensitization | Chemical Research in Toxicology | 2007 | 1,334 |
6 | Cytochrome P450 and Chemical Toxicology | Chemical Research in Toxicology | 2008 | 1,292 |
7 | Copper Oxide Nanoparticles Are Highly Toxic: A Comparison between Metal Oxide Nanoparticles and Carbon Nanotubes | Chemical Research in Toxicology | 2008 | 1,239 |
8 | Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects | Chemical Research in Toxicology | 1991 | 1,170 |
9 | Biological Interactions of Graphene-Family Nanomaterials: An Interdisciplinary Review | Chemical Research in Toxicology | 2012 | 1,131 |
10 | Structure, Catalytic Mechanism, and Evolution of the Glutathione Transferases | Chemical Research in Toxicology | 1997 | 1,038 |
11 | Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes | Chemical Research in Toxicology | 1991 | 1,003 |
12 | Biochemistry, Biology, and Carcinogenicity of Tobacco-Specific N-Nitrosamines | Chemical Research in Toxicology | 1998 | 988 |
13 | Oxidative Damage and Tyrosine Nitration from Peroxynitrite | Chemical Research in Toxicology | 1996 | 963 |
14 | Metabolism and Kinetics of Bisphenol A in Humans at Low Doses Following Oral Administration | Chemical Research in Toxicology | 2002 | 843 |
15 | Chromium in Drinking Water: Sources, Metabolism, and Cancer Risks | Chemical Research in Toxicology | 2011 | 823 |
16 | Genetic and Epigenetic Mechanisms in Metal Carcinogenesis and Cocarcinogenesis: Nickel, Arsenic, and Chromium | Chemical Research in Toxicology | 2008 | 774 |
17 | Nanotoxicity of Graphene and Graphene Oxide | Chemical Research in Toxicology | 2014 | 729 |
18 | Absolute Rate Constants for the Reaction of Hypochlorous Acid with Protein Side Chains and Peptide Bonds | Chemical Research in Toxicology | 2001 | 716 |
19 | Drug−Protein Adducts: An Industry Perspective on Minimizing the Potential for Drug Bioactivation in Drug Discovery and Development | Chemical Research in Toxicology | 2004 | 707 |
20 | Oxidative Stress and Neurotoxicity | Chemical Research in Toxicology | 2008 | 707 |
21 | Reactive Oxygen-Mediated Protein Oxidation in Aging and Disease | Chemical Research in Toxicology | 1997 | 637 |
22 | The Less Harmful Cigarette: A Controversial Issue. A Tribute to Ernst L. Wynder | Chemical Research in Toxicology | 2001 | 626 |
23 | The Search for Endogenous Activators of the Aryl Hydrocarbon Receptor | Chemical Research in Toxicology | 2008 | 621 |
24 | Formation and Properties of Peroxynitrite as Studied by Laser Flash Photolysis, High-Pressure Stopped-Flow Technique, and Pulse Radiolysis | Chemical Research in Toxicology | 1997 | 606 |
25 | Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions | Chemical Research in Toxicology | 1992 | 571 |
26 | Structural Alert/Reactive Metabolite Concept as Applied in Medicinal Chemistry to Mitigate the Risk of Idiosyncratic Drug Toxicity: A Perspective Based on the Critical Examination of Trends in the Top 200 Drugs Marketed in the United States | Chemical Research in Toxicology | 2011 | 569 |
27 | Biochemical structural and functional properties of oxidized low-density lipoprotein | Chemical Research in Toxicology | 1990 | 521 |
28 | Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450IIE1 | Chemical Research in Toxicology | 1990 | 516 |
29 | Reactions of the bioregulatory agent nitric oxide in oxygenated aqueous media: Determination of the kinetics for oxidation and nitrosation by intermediates generated in the nitric oxide/oxygen reaction | Chemical Research in Toxicology | 1993 | 497 |
30 | Importance of Chromium−DNA Adducts in Mutagenicity and Toxicity of Chromium(VI) | Chemical Research in Toxicology | 2005 | 494 |
31 | Methylated Trivalent Arsenic Species Are Genotoxic | Chemical Research in Toxicology | 2001 | 479 |
32 | Acrylamide: A Cooking Carcinogen? | Chemical Research in Toxicology | 2000 | 475 |
33 | Biotransformation Reactions of Five-Membered Aromatic Heterocyclic Rings | Chemical Research in Toxicology | 2002 | 471 |
34 | Organophosphate Toxicology: Safety Aspects of Nonacetylcholinesterase Secondary Targets | Chemical Research in Toxicology | 2004 | 465 |
35 | Integrated Metabonomic Analysis of the Multiorgan Effects of Hydrazine Toxicity in the Rat | Chemical Research in Toxicology | 2005 | 464 |
36 | ToxCast Chemical Landscape: Paving the Road to 21st Century Toxicology | Chemical Research in Toxicology | 2016 | 456 |
37 | Improving Drug Candidates by Design: A Focus on Physicochemical Properties As a Means of Improving Compound Disposition and Safety | Chemical Research in Toxicology | 2011 | 450 |
38 | Role of Free Radicals in the Toxicity of Airborne Fine Particulate Matter | Chemical Research in Toxicology | 2001 | 445 |
39 | Reactions of arsenic(III) and arsenic(V) species with glutathione | Chemical Research in Toxicology | 1993 | 441 |
40 | Mechanisms of Formation, Genotoxicity, and Mutation of Guanine Oxidation Products | Chemical Research in Toxicology | 2006 | 438 |
41 | Dihydrodiol Dehydrogenases and Polycyclic Aromatic Hydrocarbon Activation: Generation of Reactive and Redox Active o-Quinones | Chemical Research in Toxicology | 1999 | 437 |
42 | Structure−Activity Relationships for a Large Diverse Set of Natural, Synthetic, and Environmental Estrogens | Chemical Research in Toxicology | 2001 | 432 |
43 | In Vitro and in Vivo Interactions of Bisphenol A and Its Metabolite, Bisphenol A Glucuronide, with Estrogen Receptors α and β | Chemical Research in Toxicology | 2001 | 410 |
44 | Update on EPA’s ToxCast Program: Providing High Throughput Decision Support Tools for Chemical Risk Management | Chemical Research in Toxicology | 2012 | 410 |
45 | Endocrine Disrupting Chemicals Targeting Estrogen Receptor Signaling: Identification and Mechanisms of Action | Chemical Research in Toxicology | 2011 | 406 |
46 | Reactions of 1-Methyl-2-phenylindole with Malondialdehyde and 4-Hydroxyalkenals. Analytical Applications to a Colorimetric Assay of Lipid Peroxidation | Chemical Research in Toxicology | 1998 | 397 |
47 | Mutagenicity of Nitroaromatic Compounds | Chemical Research in Toxicology | 2000 | 397 |
48 | An Overview of Chemical Processes That Damage Cellular DNA: Spontaneous Hydrolysis, Alkylation, and Reactions with Radicals | Chemical Research in Toxicology | 2009 | 388 |
49 | Cytochrome P450 enzymes involved in acetaminophen activation by rat and human liver microsomes and their kinetics | Chemical Research in Toxicology | 1993 | 381 |
50 | A Quantum Chemical Explanation of the Antioxidant Activity of Flavonoids | Chemical Research in Toxicology | 1996 | 378 |