| # | Title | Journal | Year | Citations |
|---|
| 1 | Toxicity of Gold Nanoparticles Functionalized with Cationic and Anionic Side Chains | Bioconjugate Chemistry | 2004 | 1,397 |
| 2 | Polyamidoamine cascade polymers mediate efficient transfection of cells in culture | Bioconjugate Chemistry | 1993 | 1,158 |
| 3 | Theranostics: Combining Imaging and Therapy | Bioconjugate Chemistry | 2011 | 1,126 |
| 4 | Noninvasive Imaging of Quantum Dots in Mice | Bioconjugate Chemistry | 2004 | 1,045 |
| 5 | Tumor-Selective Delivery of Macromolecular Drugs via the EPR Effect: Background and Future Prospects | Bioconjugate Chemistry | 2010 | 874 |
| 6 | High-Efficiency Intracellular Magnetic Labeling with Novel Superparamagnetic-Tat Peptide Conjugates | Bioconjugate Chemistry | 1999 | 861 |
| 7 | Cyanine dye labeling reagents: Sulfoindocyanine succinimidyl esters | Bioconjugate Chemistry | 1993 | 829 |
| 8 | In Vitro Gene Delivery by Degraded Polyamidoamine Dendrimers | Bioconjugate Chemistry | 1996 | 818 |
| 9 | Nanodrug Delivery: Is the Enhanced Permeability and Retention Effect Sufficient for Curing Cancer? | Bioconjugate Chemistry | 2016 | 726 |
| 10 | 68Ga-Complex Lipophilicity and the Targeting Property of a Urea-Based PSMA Inhibitor for PET Imaging | Bioconjugate Chemistry | 2012 | 709 |
| 11 | Tetrazine-Based Cycloadditions: Application to Pretargeted Live Cell Imaging | Bioconjugate Chemistry | 2008 | 698 |
| 12 | Preparation and Biological Characterization of Polymeric Micelle Drug Carriers with Intracellular pH-Triggered Drug Release Property: Tumor Permeability, Controlled Subcellular Drug Distribution, and Enhanced in Vivo Antitumor Efficacy | Bioconjugate Chemistry | 2005 | 682 |
| 13 | Mechanism of Amide Formation by Carbodiimide for Bioconjugation in Aqueous Media | Bioconjugate Chemistry | 1995 | 630 |
| 14 | Interaction of Polycationic Polymers with Supported Lipid Bilayers and Cells: Nanoscale Hole Formation and Enhanced Membrane Permeability | Bioconjugate Chemistry | 2006 | 623 |
| 15 | Synthesis of Polyamidoamine Dendrimers Having Poly(ethylene glycol) Grafts and Their Ability To Encapsulate Anticancer Drugs | Bioconjugate Chemistry | 2000 | 608 |
| 16 | Rational Design of a Potent, Long-Lasting Form of Interferon: A 40 kDa Branched Polyethylene Glycol-Conjugated Interferon α-2a for the Treatment of Hepatitis C | Bioconjugate Chemistry | 2001 | 580 |
| 17 | Interaction of Poly(amidoamine) Dendrimers with Supported Lipid Bilayers and Cells: Hole Formation and the Relation to Transport | Bioconjugate Chemistry | 2004 | 556 |
| 18 | Conjugates of anticancer agents and polymers: advantages of macromolecular therapeutics in vivo | Bioconjugate Chemistry | 1992 | 535 |
| 19 | Antibody−Drug Conjugates: Linking Cytotoxic Payloads to Monoclonal Antibodies | Bioconjugate Chemistry | 2010 | 532 |
| 20 | A brief survey of methods for preparing protein conjugates with dyes, haptens and crosslinking reagents | Bioconjugate Chemistry | 1992 | 531 |
| 21 | Polyethylenimine-graft-Poly(ethylene glycol) Copolymers: Influence of Copolymer Block Structure on DNA Complexation and Biological Activities as Gene Delivery System | Bioconjugate Chemistry | 2002 | 516 |
| 22 | Gemtuzumab Ozogamicin, A Potent and Selective Anti-CD33 Antibody−Calicheamicin Conjugate for Treatment of Acute Myeloid Leukemia | Bioconjugate Chemistry | 2002 | 506 |
| 23 | pH-Responsive Copolymer Assemblies for Controlled Release of Doxorubicin | Bioconjugate Chemistry | 2005 | 506 |
| 24 | “SMART” Drug Delivery Systems: Double-Targeted pH-Responsive Pharmaceutical Nanocarriers | Bioconjugate Chemistry | 2006 | 504 |
| 25 | Polyester Dendritic Systems for Drug Delivery Applications: In Vitro and In Vivo Evaluation | Bioconjugate Chemistry | 2002 | 485 |
| 26 | DNA Complexes with Polycations for the Delivery of Genetic Material into Cells | Bioconjugate Chemistry | 1995 | 481 |
| 27 | Site-Specific Antibody–Drug Conjugates: The Nexus of Bioorthogonal Chemistry, Protein Engineering, and Drug Development | Bioconjugate Chemistry | 2015 | 476 |
| 28 | Efficient Gene Transfer by Histidylated Polylysine/pDNA Complexes | Bioconjugate Chemistry | 1999 | 474 |
| 29 | 1-(meta-[211At]Astatobenzyl)guanidine: synthesis via astato demetalation and preliminary in vitro and in vivo evaluation | Bioconjugate Chemistry | 1992 | 469 |
| 30 | Water-Soluble Polyion Complex Associates of DNA and Poly(ethylene glycol)−Poly(l-lysine) Block Copolymer | Bioconjugate Chemistry | 1997 | 461 |
| 31 | Functionalized Poly(ethylene glycols) for Preparation of Biologically Relevant Conjugates | Bioconjugate Chemistry | 1995 | 457 |
| 32 | Electrochemistry of Methylene Blue Bound to a DNA-Modified Electrode | Bioconjugate Chemistry | 1997 | 457 |
| 33 | Paramagnetic Water-Soluble Metallofullerenes Having the Highest Relaxivity for MRI Contrast Agents | Bioconjugate Chemistry | 2001 | 450 |
| 34 | Enhanced Activity of Monomethylauristatin F through Monoclonal Antibody Delivery: Effects of Linker Technology on Efficacy and Toxicity | Bioconjugate Chemistry | 2006 | 448 |
| 35 | Efficient Gene Transfer Using Reversibly Cross-Linked Low Molecular Weight Polyethylenimine | Bioconjugate Chemistry | 2001 | 444 |
| 36 | The Controlled Display of Biomolecules on Nanoparticles: A Challenge Suited to Bioorthogonal Chemistry | Bioconjugate Chemistry | 2011 | 444 |
| 37 | Folate-Conjugated Iron Oxide Nanoparticles for Solid Tumor Targeting as Potential Specific Magnetic Hyperthermia Mediators: Synthesis, Physicochemical Characterization, and in Vitro Experiments | Bioconjugate Chemistry | 2005 | 439 |
| 38 | Stearylated Arginine-Rich Peptides: A New Class of Transfection Systems | Bioconjugate Chemistry | 2001 | 428 |
| 39 | Cathepsin B-Labile Dipeptide Linkers for Lysosomal Release of Doxorubicin from Internalizing Immunoconjugates: Model Studies of Enzymatic Drug Release and Antigen-Specific In Vitro Anticancer Activity | Bioconjugate Chemistry | 2002 | 427 |
| 40 | Targeting Folate Receptor with Folate Linked to Extremities of Poly(ethylene glycol)-Grafted Liposomes: In Vitro Studies | Bioconjugate Chemistry | 1999 | 423 |
| 41 | Conjugates of oligonucleotides and modified oligonucleotides: a review of their synthesis and properties | Bioconjugate Chemistry | 1990 | 416 |
| 42 | Cellular Trajectories of Peptide-Modified Gold Particle Complexes: Comparison of Nuclear Localization Signals and Peptide Transduction Domains | Bioconjugate Chemistry | 2004 | 415 |
| 43 | Simple Modifications of Branched PEI Lead to Highly Efficient siRNA Carriers with Low Toxicity | Bioconjugate Chemistry | 2008 | 411 |
| 44 | Structure−Activity Relationships of Water-Soluble Cationic Methacrylate/Methacrylamide Polymers for Nonviral Gene Delivery | Bioconjugate Chemistry | 1999 | 403 |
| 45 | Gold Nanoparticle-Mediated Transfection of Mammalian Cells | Bioconjugate Chemistry | 2002 | 400 |
| 46 | Biodegradable Polymers for Protein and Peptide Drug Delivery | Bioconjugate Chemistry | 1995 | 398 |
| 47 | Contribution of Linker Stability to the Activities of Anticancer Immunoconjugates | Bioconjugate Chemistry | 2008 | 395 |
| 48 | NanoLuc: A Small Luciferase Is Brightening Up the Field of Bioluminescence | Bioconjugate Chemistry | 2016 | 383 |
| 49 | The Endosomal Escape of Nanoparticles: Toward More Efficient Cellular Delivery | Bioconjugate Chemistry | 2019 | 380 |
| 50 | Gene Transfer with Synthetic Cationic Amphiphiles: Prospects for Gene Therapy | Bioconjugate Chemistry | 1994 | 372 |
