| # | Title | Journal | Year | Citations |
|---|
| 1 | Neutrophil Extracellular Traps Contain Calprotectin, a Cytosolic Protein Complex Involved in Host Defense against Candida albicans | PLoS Pathogens | 2009 | 1,378 |
| 2 | Influenza Virus Transmission Is Dependent on Relative Humidity and Temperature | PLoS Pathogens | 2007 | 1,259 |
| 3 | Selection of Resistant Bacteria at Very Low Antibiotic Concentrations | PLoS Pathogens | 2011 | 1,248 |
| 4 | A Single Mutation in Chikungunya Virus Affects Vector Specificity and Epidemic Potential | PLoS Pathogens | 2007 | 1,228 |
| 5 | New World Bats Harbor Diverse Influenza A Viruses | PLoS Pathogens | 2013 | 1,050 |
| 6 | High-Resolution Phenotypic Profiling Defines Genes Essential for Mycobacterial Growth and Cholesterol Catabolism | PLoS Pathogens | 2011 | 935 |
| 7 | Post-Treatment HIV-1 Controllers with a Long-Term Virological Remission after the Interruption of Early Initiated Antiretroviral Therapy ANRS VISCONTI Study | PLoS Pathogens | 2013 | 879 |
| 8 | Characterization of the Oral Fungal Microbiome (Mycobiome) in Healthy Individuals | PLoS Pathogens | 2010 | 869 |
| 9 | A Next-Generation Cleaved, Soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, Expresses Multiple Epitopes for Broadly Neutralizing but Not Non-Neutralizing Antibodies | PLoS Pathogens | 2013 | 835 |
| 10 | Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus | PLoS Pathogens | 2017 | 797 |
| 11 | The Aedes aegypti Toll Pathway Controls Dengue Virus Infection | PLoS Pathogens | 2008 | 765 |
| 12 | agr-Mediated Dispersal of Staphylococcus aureus Biofilms | PLoS Pathogens | 2008 | 749 |
| 13 | Quasispecies Theory and the Behavior of RNA Viruses | PLoS Pathogens | 2010 | 717 |
| 14 | The Battle for Iron between Bacterial Pathogens and Their Vertebrate Hosts | PLoS Pathogens | 2010 | 716 |
| 15 | Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2 | PLoS Pathogens | 2018 | 716 |
| 16 | Zn2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture | PLoS Pathogens | 2010 | 685 |
| 17 | Arginase-1–Expressing Macrophages Suppress Th2 Cytokine–Driven Inflammation and Fibrosis | PLoS Pathogens | 2009 | 673 |
| 18 | IFN-Lambda (IFN-λ) Is Expressed in a Tissue-Dependent Fashion and Primarily Acts on Epithelial Cells In Vivo | PLoS Pathogens | 2008 | 672 |
| 19 | Implication of the Mosquito Midgut Microbiota in the Defense against Malaria Parasites | PLoS Pathogens | 2009 | 661 |
| 20 | A Genomic Approach to Identify Regulatory Nodes in the Transcriptional Network of Systemic Acquired Resistance in Plants | PLoS Pathogens | 2006 | 651 |
| 21 | The Endosymbiotic Bacterium Wolbachia Induces Resistance to Dengue Virus in Aedes aegypti | PLoS Pathogens | 2010 | 618 |
| 22 | Seroepidemiology of Human Polyomaviruses | PLoS Pathogens | 2009 | 608 |
| 23 | Foamy Macrophages from Tuberculous Patients' Granulomas Constitute a Nutrient-Rich Reservoir for M. tuberculosis Persistence | PLoS Pathogens | 2008 | 606 |
| 24 | Diverse Lifestyles and Strategies of Plant Pathogenesis Encoded in the Genomes of Eighteen Dothideomycetes Fungi | PLoS Pathogens | 2012 | 595 |
| 25 | Spatial, Temporal, and Species Variation in Prevalence of Influenza A Viruses in Wild Migratory Birds | PLoS Pathogens | 2007 | 591 |
| 26 | Identification of a Novel Polyomavirus from Patients with Acute Respiratory Tract Infections | PLoS Pathogens | 2007 | 581 |
| 27 | Multilocus Sequence Typing as a Replacement for Serotyping in Salmonella enterica | PLoS Pathogens | 2012 | 574 |
| 28 | Extracellular DNA Chelates Cations and Induces Antibiotic Resistance in Pseudomonas aeruginosa Biofilms | PLoS Pathogens | 2008 | 558 |
| 29 | Influenza Virus Aerosols in Human Exhaled Breath: Particle Size, Culturability, and Effect of Surgical Masks | PLoS Pathogens | 2013 | 557 |
| 30 | H5N1 and 1918 Pandemic Influenza Virus Infection Results in Early and Excessive Infiltration of Macrophages and Neutrophils in the Lungs of Mice | PLoS Pathogens | 2008 | 552 |
| 31 | Isolation of Genetically Diverse Marburg Viruses from Egyptian Fruit Bats | PLoS Pathogens | 2009 | 549 |
| 32 | Tuberculosis and HIV Co-Infection | PLoS Pathogens | 2012 | 549 |
| 33 | Neutrophils: Between Host Defence, Immune Modulation, and Tissue Injury | PLoS Pathogens | 2015 | 532 |
| 34 | Comparative Analysis of Measures of Viral Reservoirs in HIV-1 Eradication Studies | PLoS Pathogens | 2013 | 524 |
| 35 | From bacterial killing to immune modulation: Recent insights into the functions of lysozyme | PLoS Pathogens | 2017 | 523 |
| 36 | A New Perspective on Listeria monocytogenes Evolution | PLoS Pathogens | 2008 | 518 |
| 37 | Distinct Patterns of IFITM-Mediated Restriction of Filoviruses, SARS Coronavirus, and Influenza A Virus | PLoS Pathogens | 2011 | 518 |
| 38 | Assembly and Development of the Pseudomonas aeruginosa Biofilm Matrix | PLoS Pathogens | 2009 | 515 |
| 39 | Viral and Bacterial Interactions in the Upper Respiratory Tract | PLoS Pathogens | 2013 | 511 |
| 40 | A Mouse Model for Chikungunya: Young Age and Inefficient Type-I Interferon Signaling Are Risk Factors for Severe Disease | PLoS Pathogens | 2008 | 506 |
| 41 | Identification of a Novel Gammaretrovirus in Prostate Tumors of Patients Homozygous for R462Q RNASEL Variant | PLoS Pathogens | 2006 | 504 |
| 42 | Targeted Restoration of the Intestinal Microbiota with a Simple, Defined Bacteriotherapy Resolves Relapsing Clostridium difficile Disease in Mice | PLoS Pathogens | 2012 | 504 |
| 43 | Muc2 Protects against Lethal Infectious Colitis by Disassociating Pathogenic and Commensal Bacteria from the Colonic Mucosa | PLoS Pathogens | 2010 | 501 |
| 44 | Candida auris: A rapidly emerging cause of hospital-acquired multidrug-resistant fungal infections globally | PLoS Pathogens | 2017 | 501 |
| 45 | Transmission of Influenza Virus in a Mammalian Host Is Increased by PB2 Amino Acids 627K or 627E/701N | PLoS Pathogens | 2009 | 497 |
| 46 | HIV-Infected Individuals with Low CD4/CD8 Ratio despite Effective Antiretroviral Therapy Exhibit Altered T Cell Subsets, Heightened CD8+ T Cell Activation, and Increased Risk of Non-AIDS Morbidity and Mortality | PLoS Pathogens | 2014 | 495 |
| 47 | NetB, a New Toxin That Is Associated with Avian Necrotic Enteritis Caused by Clostridium perfringens | PLoS Pathogens | 2008 | 494 |
| 48 | Exposure to HIV-1 Directly Impairs Mucosal Epithelial Barrier Integrity Allowing Microbial Translocation | PLoS Pathogens | 2010 | 488 |
| 49 | Epstein–Barr Virus MicroRNAs Are Evolutionarily Conserved and Differentially Expressed | PLoS Pathogens | 2006 | 486 |
| 50 | Long-Distance Delivery of Bacterial Virulence Factors by Pseudomonas aeruginosa Outer Membrane Vesicles | PLoS Pathogens | 2009 | 486 |
