| # | Title | Journal | Year | Citations |
|---|
| 1 | Drug Resistance in Cancer: An Overview | Cancers | 2014 | 1,810 |
| 2 | Cisplatin as an Anti-Tumor Drug: Cellular Mechanisms of Activity, Drug Resistance and Induced Side Effects | Cancers | 2011 | 1,314 |
| 3 | Tumor-Associated Macrophages as Major Players in the Tumor Microenvironment | Cancers | 2014 | 1,223 |
| 4 | Epidermal Growth Factor Receptor Cell Proliferation Signaling Pathways | Cancers | 2017 | 1,153 |
| 5 | Review of Indications of FDA-Approved Immune Checkpoint Inhibitors per NCCN Guidelines with the Level of Evidence | Cancers | 2020 | 826 |
| 6 | Oncologic Photodynamic Therapy: Basic Principles, Current Clinical Status and Future Directions | Cancers | 2017 | 694 |
| 7 | Assessment of the Evolution of Cancer Treatment Therapies | Cancers | 2011 | 624 |
| 8 | Cancer-Associated Fibroblasts: Their Characteristics and Their Roles in Tumor Growth | Cancers | 2015 | 616 |
| 9 | Cytokines in Cancer Immunotherapy | Cancers | 2011 | 549 |
| 10 | Cell Death Pathways in Photodynamic Therapy of Cancer | Cancers | 2011 | 548 |
| 11 | A Comprehensive Review on MAPK: A Promising Therapeutic Target in Cancer | Cancers | 2019 | 517 |
| 12 | Targeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI Inhibitors | Cancers | 2016 | 476 |
| 13 | Role of p53 in Cell Death and Human Cancers | Cancers | 2011 | 453 |
| 14 | Active Targeting Strategies Using Biological Ligands for Nanoparticle Drug Delivery Systems | Cancers | 2019 | 441 |
| 15 | Flavonoids in Cancer and Apoptosis | Cancers | 2019 | 441 |
| 16 | Breast Cancer—Epidemiology, Risk Factors, Classification, Prognostic Markers, and Current Treatment Strategies—An Updated Review | Cancers | 2021 | 441 |
| 17 | STAT3 Target Genes Relevant to Human Cancers | Cancers | 2014 | 398 |
| 18 | Different Subsets of T Cells, Memory, Effector Functions, and CAR-T Immunotherapy | Cancers | 2016 | 396 |
| 19 | Gut Microbiota and Cancer: From Pathogenesis to Therapy | Cancers | 2019 | 378 |
| 20 | Cancer-Associated Thrombosis: An Overview of Mechanisms, Risk Factors, and Treatment | Cancers | 2018 | 373 |
| 21 | JAK-STAT Signaling: A Double-Edged Sword of Immune Regulation and Cancer Progression | Cancers | 2019 | 369 |
| 22 | Regulation of EMT in Colorectal Cancer: A Culprit in Metastasis | Cancers | 2017 | 365 |
| 23 | Pancreatic Cancer Chemoresistance to Gemcitabine | Cancers | 2017 | 316 |
| 24 | Exploring the Role of RGD-Recognizing Integrins in Cancer | Cancers | 2017 | 308 |
| 25 | A Novel Gene Signature-Based Model Predicts Biochemical Recurrence-Free Survival in Prostate Cancer Patients after Radical Prostatectomy | Cancers | 2020 | 300 |
| 26 | Cancer Stem Cells and Epithelial-to-Mesenchymal Transition (EMT)-Phenotypic Cells: Are They Cousins or Twins? | Cancers | 2011 | 299 |
| 27 | A Review of Colorectal Cancer in Terms of Epidemiology, Risk Factors, Development, Symptoms and Diagnosis | Cancers | 2021 | 299 |
| 28 | Targeting RTK Signaling Pathways in Cancer | Cancers | 2015 | 290 |
| 29 | Reactive Oxygen Species in the Tumor Microenvironment: An Overview | Cancers | 2019 | 288 |
| 30 | Tyrosine Kinase Inhibitors in Cancer: Breakthrough and Challenges of Targeted Therapy | Cancers | 2020 | 280 |
| 31 | Exosomes in Cancer Diagnostics | Cancers | 2017 | 275 |
| 32 | Annotating Cancer Variants and Anti-Cancer Therapeutics in Reactome | Cancers | 2012 | 270 |
| 33 | Cancer Diagnosis Using Deep Learning: A Bibliographic Review | Cancers | 2019 | 268 |
| 34 | Effects of Age on the Detection and Management of Breast Cancer | Cancers | 2015 | 263 |
| 35 | Lung Cancers: Molecular Characterization, Clonal Heterogeneity and Evolution, and Cancer Stem Cells | Cancers | 2018 | 258 |
| 36 | Targeting Cyclin-Dependent Kinases in Human Cancers: From Small Molecules to Peptide Inhibitors | Cancers | 2015 | 257 |
| 37 | p53 Acetylation: Regulation and Consequences | Cancers | 2015 | 256 |
| 38 | A Review on a Deep Learning Perspective in Brain Cancer Classification | Cancers | 2019 | 253 |
| 39 | The Epithelial-to-Mesenchymal Transition in Cancer | Cancers | 2018 | 251 |
| 40 | Glutathione in Cancer Cell Death | Cancers | 2011 | 247 |
| 41 | Tumor-Associated Neutrophils in Cancer: Going Pro | Cancers | 2019 | 245 |
| 42 | Coumarins and Coumarin-Related Compounds in Pharmacotherapy of Cancer | Cancers | 2020 | 244 |
| 43 | Transcription Factor STAT3 as a Novel Molecular Target for Cancer Prevention | Cancers | 2014 | 234 |
| 44 | The p53 Pathway in Glioblastoma | Cancers | 2018 | 232 |
| 45 | The Landscape of Targeted Therapies in TNBC | Cancers | 2020 | 232 |
| 46 | Positron Emission Tomography (PET) in Oncology | Cancers | 2014 | 231 |
| 47 | Isolation of Circulating Tumor Cells by Dielectrophoresis | Cancers | 2014 | 223 |
| 48 | Mixed Adenoneuroendocrine Carcinomas (MANECs) of the Gastrointestinal Tract: An Update | Cancers | 2012 | 220 |
| 49 | mTOR Pathways in Cancer and Autophagy | Cancers | 2018 | 219 |
| 50 | The Application of Deep Learning in Cancer Prognosis Prediction | Cancers | 2020 | 218 |
