8.9(top 2%)
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papers
590.6K(top 1%)
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350(top 1%)
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9.0(top 2%)
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9.0K
all documents
619.5K
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531(top 1%)
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Top Articles

#TitleJournalYearCitations
1The Warburg Effect: How Does it Benefit Cancer Cells?Trends in Biochemical Sciences20163,019
2Multiple sequence alignment with Clustal XTrends in Biochemical Sciences19982,468
3RASMOL: biomolecular graphics for allTrends in Biochemical Sciences19952,429
4Structure, mechanism and regulation of peroxiredoxinsTrends in Biochemical Sciences20032,285
5Genomic DNA methylation: the mark and its mediatorsTrends in Biochemical Sciences20062,190
6Caspases: killer proteasesTrends in Biochemical Sciences19972,182
7Oxidative stress shortens telomeresTrends in Biochemical Sciences20022,129
8The P-loop — a common motif in ATP- and GTP-binding proteinsTrends in Biochemical Sciences19901,999
9Mechanism and Regulation of NLRP3 Inflammasome ActivationTrends in Biochemical Sciences20161,993
10PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localizationTrends in Biochemical Sciences19991,991
11Macromolecular crowding: obvious but underappreciatedTrends in Biochemical Sciences20011,986
12Nuclear targeting sequences — a consensus?Trends in Biochemical Sciences19911,953
13Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell DeathTrends in Biochemical Sciences20171,911
14Intrinsically unstructured proteinsTrends in Biochemical Sciences20021,868
15Protein misfolding, evolution and diseaseTrends in Biochemical Sciences19991,858
16AU-rich elements: characterization and importance in mRNA degradationTrends in Biochemical Sciences19951,834
17The economics of ribosome biosynthesis in yeastTrends in Biochemical Sciences19991,662
18The Nrf2 regulatory network provides an interface between redox and intermediary metabolismTrends in Biochemical Sciences20141,591
19NPS@: Network Protein Sequence AnalysisTrends in Biochemical Sciences20001,468
20PEST sequences and regulation by proteolysisTrends in Biochemical Sciences19961,461
21The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensationTrends in Biochemical Sciences20111,423
22Glutamine addiction: a new therapeutic target in cancerTrends in Biochemical Sciences20101,422
23The glamour and gloom of glycogen synthase kinase-3Trends in Biochemical Sciences20041,400
24Dali: a network tool for protein structure comparisonTrends in Biochemical Sciences19951,390
25Okadaic acid: a new probe for the study of cellular regulationTrends in Biochemical Sciences19901,332
26Phosphorylation of NF-κB and IκB proteins: implications in cancer and inflammationTrends in Biochemical Sciences20051,285
27Understanding, improving and using green fluorescent proteinsTrends in Biochemical Sciences19951,284
28Promoter-specific activation of RNA polymerase II transcription by Sp1Trends in Biochemical Sciences19861,181
29The leucine-rich repeat: a versatile binding motifTrends in Biochemical Sciences19941,172
30The regulation of protein function by multisite phosphorylation – a 25 year updateTrends in Biochemical Sciences20001,108
31The WD repeat: a common architecture for diverse functionsTrends in Biochemical Sciences19991,101
32New insights into TGF-β–Smad signallingTrends in Biochemical Sciences20041,097
33The ‘Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signalingTrends in Biochemical Sciences20031,093
34Ten years of protein kinase B signalling: a hard Akt to followTrends in Biochemical Sciences20011,091
35Regulation of autophagy by ROS: physiology and pathologyTrends in Biochemical Sciences20111,076
36Mammalian cyclin-dependent kinasesTrends in Biochemical Sciences20051,069
37Coiled coils: new structures and new functionsTrends in Biochemical Sciences19961,067
38The MAP kinase cascade is essential for diverse signal transduction pathwaysTrends in Biochemical Sciences19931,061
39The measurement and mechanism of lipid peroxidation in biological systemsTrends in Biochemical Sciences19901,052
40Protein kinase recognition sequence motifsTrends in Biochemical Sciences19901,036
41The pentose phosphate pathway and cancerTrends in Biochemical Sciences20141,018
42Moonlighting proteinsTrends in Biochemical Sciences19991,017
43The AMP-activated protein kinase cascade – a unifying system for energy controlTrends in Biochemical Sciences20041,015
44A rule for termination-codon position within intron-containing genes: when nonsense affects RNA abundanceTrends in Biochemical Sciences1998999
45TPR proteins: the versatile helixTrends in Biochemical Sciences2003994
46Conservation of gene order: a fingerprint of proteins that physically interactTrends in Biochemical Sciences1998991
47Oncogenic alterations of metabolismTrends in Biochemical Sciences1999989
48G proteinsTrends in Biochemical Sciences1992984
49Parallel signal processing among mammalian MAPKsTrends in Biochemical Sciences1995968
50Ion motive ATPases. I. Ubiquity, properties, and significance to cell functionTrends in Biochemical Sciences1987966