| # | Title | Journal | Year | Citations |
|---|
| 1 | The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety | Frontiers in Pharmacology | 2014 | 1,836 |
| 2 | Advances and Challenges of Liposome Assisted Drug Delivery | Frontiers in Pharmacology | 2015 | 1,668 |
| 3 | PD-1 and PD-L1 Checkpoint Signaling Inhibition for Cancer Immunotherapy: Mechanism, Combinations, and Clinical Outcome | Frontiers in Pharmacology | 2017 | 1,276 |
| 4 | Three-Dimensional in Vitro Cell Culture Models in Drug Discovery and Drug Repositioning | Frontiers in Pharmacology | 2018 | 1,038 |
| 5 | Toxic Mechanisms of Five Heavy Metals: Mercury, Lead, Chromium, Cadmium, and Arsenic | Frontiers in Pharmacology | 2021 | 870 |
| 6 | Network Pharmacology Databases for Traditional Chinese Medicine: Review and Assessment | Frontiers in Pharmacology | 2019 | 731 |
| 7 | Fibroblasts in fibrosis: novel roles and mediators | Frontiers in Pharmacology | 2014 | 730 |
| 8 | Antioxidant and Oxidative Stress: A Mutual Interplay in Age-Related Diseases | Frontiers in Pharmacology | 2018 | 681 |
| 9 | NLRP3 inflammasome and its inhibitors: a review | Frontiers in Pharmacology | 2015 | 620 |
| 10 | Editorial: Adverse Effects of Cancer Chemotherapy: Anything New to Improve Tolerance and Reduce Sequelae? | Frontiers in Pharmacology | 2018 | 611 |
| 11 | Exopolysaccharide Produced by Probiotic Strain Lactobacillus paraplantarum BGCG11 Reduces Inflammatory Hyperalgesia in Rats | Frontiers in Pharmacology | 2018 | 607 |
| 12 | Evolution of Cancer Pharmacological Treatments at the Turn of the Third Millennium | Frontiers in Pharmacology | 2018 | 602 |
| 13 | Current Trends and Challenges in the Clinical Translation of Nanoparticulate Nanomedicines: Pathways for Translational Development and Commercialization | Frontiers in Pharmacology | 2018 | 586 |
| 14 | Glutathione: new roles in redox signaling for an old antioxidant | Frontiers in Pharmacology | 2014 | 571 |
| 15 | Phytochemicals in Cancer Treatment: From Preclinical Studies to Clinical Practice | Frontiers in Pharmacology | 2019 | 511 |
| 16 | Mechanisms and insights into drug resistance in cancer | Frontiers in Pharmacology | 2013 | 503 |
| 17 | Determinants of patient adherence: a review of systematic reviews | Frontiers in Pharmacology | 2013 | 482 |
| 18 | An Overview of Pickering Emulsions: Solid-Particle Materials, Classification, Morphology, and Applications | Frontiers in Pharmacology | 2017 | 481 |
| 19 | Current Diagnosis and Management of Immune Related Adverse Events (irAEs) Induced by Immune Checkpoint Inhibitor Therapy | Frontiers in Pharmacology | 2017 | 459 |
| 20 | Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression | Frontiers in Pharmacology | 2017 | 454 |
| 21 | Carbon-Based Nanomaterials for Biomedical Applications: A Recent Study | Frontiers in Pharmacology | 2018 | 432 |
| 22 | Neuroinflammation as a Common Feature of Neurodegenerative Disorders | Frontiers in Pharmacology | 2019 | 430 |
| 23 | Nanomaterials in Targeting Cancer Stem Cells for Cancer Therapy | Frontiers in Pharmacology | 2017 | 429 |
| 24 | Glutathione and mitochondria | Frontiers in Pharmacology | 2014 | 401 |
| 25 | Bridging Molecular Docking to Molecular Dynamics in Exploring Ligand-Protein Recognition Process: An Overview | Frontiers in Pharmacology | 2018 | 401 |
| 26 | Targeting TGF-β Mediated SMAD Signaling for the Prevention of Fibrosis | Frontiers in Pharmacology | 2017 | 393 |
| 27 | Barrier Mechanisms in the Developing Brain | Frontiers in Pharmacology | 2012 | 378 |
| 28 | PLGA-Based Nanoparticles in Cancer Treatment | Frontiers in Pharmacology | 2018 | 372 |
| 29 | Anticancer Targets in the Glycolytic Metabolism of Tumors: A Comprehensive Review | Frontiers in Pharmacology | 2011 | 367 |
| 30 | RSL3 Drives Ferroptosis Through GPX4 Inactivation and ROS Production in Colorectal Cancer | Frontiers in Pharmacology | 2018 | 361 |
| 31 | GPCR Signaling Regulation: The Role of GRKs and Arrestins | Frontiers in Pharmacology | 2019 | 358 |
| 32 | Multifunctional polymeric micelles for delivery of drugs and siRNA | Frontiers in Pharmacology | 2014 | 354 |
| 33 | Immune-Related Adverse Events Associated with Anti-PD-1/PD-L1 Treatment for Malignancies: A Meta-Analysis | Frontiers in Pharmacology | 2017 | 350 |
| 34 | The Ketogenic Diet as a Treatment Paradigm for Diverse Neurological Disorders | Frontiers in Pharmacology | 2012 | 347 |
| 35 | Heme Oxygenase-1, Oxidation, Inflammation, and Atherosclerosis | Frontiers in Pharmacology | 2012 | 346 |
| 36 | Turmeric and Its Major Compound Curcumin on Health: Bioactive Effects and Safety Profiles for Food, Pharmaceutical, Biotechnological and Medicinal Applications | Frontiers in Pharmacology | 2020 | 345 |
| 37 | Resveratrol: French Paradox Revisited | Frontiers in Pharmacology | 2012 | 344 |
| 38 | Biologically Targeted Magnetic Hyperthermia: Potential and Limitations | Frontiers in Pharmacology | 2018 | 340 |
| 39 | Phosphodiesterase-4 Inhibitors for the Treatment of Inflammatory Diseases | Frontiers in Pharmacology | 2018 | 328 |
| 40 | A Systematic Review on the Pharmacokinetics of Cannabidiol in Humans | Frontiers in Pharmacology | 2018 | 326 |
| 41 | The Bone Extracellular Matrix in Bone Formation and Regeneration | Frontiers in Pharmacology | 2020 | 326 |
| 42 | Nanoparticles in the Treatment of Infections Caused by Multidrug-Resistant Organisms | Frontiers in Pharmacology | 2019 | 320 |
| 43 | Physiologic and pharmacokinetic changes in pregnancy | Frontiers in Pharmacology | 2014 | 316 |
| 44 | Therapeutic Potential of Moringa oleifera Leaves in Chronic Hyperglycemia and Dyslipidemia: A Review | Frontiers in Pharmacology | 2012 | 307 |
| 45 | The P2X7 Receptor in Inflammatory Diseases: Angel or Demon? | Frontiers in Pharmacology | 2018 | 307 |
| 46 | Antimicrobial Peptides and Their Therapeutic Potential for Bacterial Skin Infections and Wounds | Frontiers in Pharmacology | 2018 | 307 |
| 47 | Heme in pathophysiology: a matter of scavenging, metabolism and trafficking across cell membranes | Frontiers in Pharmacology | 2014 | 305 |
| 48 | Advances in Oral Drug Delivery | Frontiers in Pharmacology | 2021 | 305 |
| 49 | The Role of Ferroptosis in Cancer Development and Treatment Response | Frontiers in Pharmacology | 2017 | 304 |
| 50 | Aldose Reductase, Oxidative Stress, and Diabetic Mellitus | Frontiers in Pharmacology | 2012 | 303 |
