| # | Title | Journal | Year | Citations |
|---|
| 1 | Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade | Cell Reports | 2017 | 2,953 |
| 2 | Formation of Chromosomal Domains by Loop Extrusion | Cell Reports | 2016 | 1,570 |
| 3 | A GAL4-Driver Line Resource for Drosophila Neurobiology | Cell Reports | 2012 | 1,287 |
| 4 | Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression | Cell Reports | 2017 | 1,256 |
| 5 | Deciphering Signatures of Mutational Processes Operative in Human Cancer | Cell Reports | 2013 | 1,087 |
| 6 | Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity | Cell Reports | 2015 | 1,083 |
| 7 | CEL-Seq: Single-Cell RNA-Seq by Multiplexed Linear Amplification | Cell Reports | 2012 | 1,071 |
| 8 | m 6 A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells | Cell Reports | 2017 | 1,026 |
| 9 | Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites | Cell Reports | 2014 | 972 |
| 10 | Analysis of Intron Sequences Reveals Hallmarks of Circular RNA Biogenesis in Animals | Cell Reports | 2015 | 918 |
| 11 | Genome-wide Analysis of Drosophila Circular RNAs Reveals Their Structural and Sequence Properties and Age-Dependent Neural Accumulation | Cell Reports | 2014 | 866 |
| 12 | Ultradeep Human Phosphoproteome Reveals a Distinct Regulatory Nature of Tyr and Ser/Thr-Based Signaling | Cell Reports | 2014 | 839 |
| 13 | Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas | Cell Reports | 2018 | 801 |
| 14 | Highly Efficient Targeted Mutagenesis of Drosophila with the CRISPR/Cas9 System | Cell Reports | 2013 | 792 |
| 15 | Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites | Cell Reports | 2017 | 792 |
| 16 | A Tissue-Mapped Axolotl De Novo Transcriptome Enables Identification of Limb Regeneration Factors | Cell Reports | 2017 | 752 |
| 17 | A Compendium of Chromatin Contact Maps Reveals Spatially Active Regions in the Human Genome | Cell Reports | 2016 | 745 |
| 18 | Evasion of Type I Interferon by SARS-CoV-2 | Cell Reports | 2020 | 742 |
| 19 | Single-Cell RNA-Seq Analysis of Infiltrating Neoplastic Cells at the Migrating Front of Human Glioblastoma | Cell Reports | 2017 | 701 |
| 20 | The Arabidopsis NPR1 Protein Is a Receptor for the Plant Defense Hormone Salicylic Acid | Cell Reports | 2012 | 684 |
| 21 | Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images | Cell Reports | 2018 | 683 |
| 22 | Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma | Cell Reports | 2016 | 671 |
| 23 | Exon Circularization Requires Canonical Splice Signals | Cell Reports | 2015 | 667 |
| 24 | MLKL Compromises Plasma Membrane Integrity by Binding to Phosphatidylinositol Phosphates | Cell Reports | 2014 | 656 |
| 25 | Comparative Hi-C Reveals that CTCF Underlies Evolution of Chromosomal Domain Architecture | Cell Reports | 2015 | 648 |
| 26 | Phenotypic Diversity and Plasticity in Circulating Neutrophil Subpopulations in Cancer | Cell Reports | 2015 | 640 |
| 27 | Parabacteroides distasonis Alleviates Obesity and Metabolic Dysfunctions via Production of Succinate and Secondary Bile Acids | Cell Reports | 2019 | 630 |
| 28 | Lysine Succinylation Is a Frequently Occurring Modification in Prokaryotes and Eukaryotes and Extensively Overlaps with Acetylation | Cell Reports | 2013 | 619 |
| 29 | The Innate Immune DNA Sensor cGAS Produces a Noncanonical Cyclic Dinucleotide that Activates Human STING | Cell Reports | 2013 | 610 |
| 30 | The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity | Cell Reports | 2017 | 608 |
| 31 | Generation of Regionally Specified Neural Progenitors and Functional Neurons from Human Embryonic Stem Cells under Defined Conditions | Cell Reports | 2012 | 595 |
| 32 | Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages | Cell Reports | 2016 | 595 |
| 33 | Ribosome Profiling Reveals Pervasive Translation Outside of Annotated Protein-Coding Genes | Cell Reports | 2014 | 591 |
| 34 | RNA-Seq Signatures Normalized by mRNA Abundance Allow Absolute Deconvolution of Human Immune Cell Types | Cell Reports | 2019 | 590 |
| 35 | Intrinsic Membrane Hyperexcitability of Amyotrophic Lateral Sclerosis Patient-Derived Motor Neurons | Cell Reports | 2014 | 583 |
| 36 | Recurrent Somatic Structural Variations Contribute to Tumorigenesis in Pediatric Osteosarcoma | Cell Reports | 2014 | 583 |
| 37 | Early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients | Cell Reports | 2021 | 568 |
| 38 | Psychedelics Promote Structural and Functional Neural Plasticity | Cell Reports | 2018 | 566 |
| 39 | Principles of Long Noncoding RNA Evolution Derived from Direct Comparison of Transcriptomes in 17 Species | Cell Reports | 2015 | 565 |
| 40 | An Optimized microRNA Backbone for Effective Single-Copy RNAi | Cell Reports | 2013 | 563 |
| 41 | A Myeloperoxidase-Containing Complex Regulates Neutrophil Elastase Release and Actin Dynamics during NETosis | Cell Reports | 2014 | 556 |
| 42 | A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia | Cell Reports | 2016 | 556 |
| 43 | A Neurodegeneration-Specific Gene-Expression Signature of Acutely Isolated Microglia from an Amyotrophic Lateral Sclerosis Mouse Model | Cell Reports | 2013 | 552 |
| 44 | A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing | Cell Reports | 2018 | 543 |
| 45 | The lncRNA Malat1 Is Dispensable for Mouse Development but Its Transcription Plays a cis-Regulatory Role in the Adult | Cell Reports | 2012 | 542 |
| 46 | Endocrine-Therapy-Resistant ESR1 Variants Revealed by Genomic Characterization of Breast-Cancer-Derived Xenografts | Cell Reports | 2013 | 539 |
| 47 | Temporal Tracking of Microglia Activation in Neurodegeneration at Single-Cell Resolution | Cell Reports | 2017 | 538 |
| 48 | Self-Organization of Polarized Cerebellar Tissue in 3D Culture of Human Pluripotent Stem Cells | Cell Reports | 2015 | 531 |
| 49 | The Major Risk Factors for Alzheimer’s Disease: Age, Sex, and Genes Modulate the Microglia Response to Aβ Plaques | Cell Reports | 2019 | 527 |
| 50 | Microglia Modulate Wiring of the Embryonic Forebrain | Cell Reports | 2014 | 526 |
