| # | Title | Journal | Year | Citations |
|---|
| 1 | LPS/TLR4 signal transduction pathway | Cytokine | 2008 | 2,424 |
| 2 | T cell subsets and their signature cytokines in autoimmune and inflammatory diseases | Cytokine | 2015 | 810 |
| 3 | Biology of the rantes/sis cytokine family | Cytokine | 1991 | 684 |
| 4 | IDENTIFICATION OF POLYMORPHISMS WITHIN THE VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) GENE: CORRELATION WITH VARIATION IN VEGF PROTEIN PRODUCTION | Cytokine | 2000 | 679 |
| 5 | Chimeric anti-TNF-α monoclonal antibody cA2 binds recombinant transmembrane TNF-α and activates immune effector functions | Cytokine | 1995 | 673 |
| 6 | THE EFFECTS OF PSYCHOLOGICAL STRESS ON HUMANS: INCREASED PRODUCTION OF PRO-INFLAMMATORY CYTOKINES AND Th1-LIKE RESPONSE IN STRESS-INDUCED ANXIETY | Cytokine | 1998 | 653 |
| 7 | INCREASED SERUM IL-6 AND IL-1 RECEPTOR ANTAGONIST CONCENTRATIONS IN MAJOR DEPRESSION AND TREATMENT RESISTANT DEPRESSION | Cytokine | 1997 | 648 |
| 8 | Interleukin 8 and MCAF: novel inflammatory cytokines inducible by IL 1 and TNF | Cytokine | 1989 | 581 |
| 9 | QUANTIFICATION OF MURINE CYTOKINE mRNAs USING REAL TIME QUANTITATIVE REVERSE TRANSCRIPTASE PCR | Cytokine | 1999 | 531 |
| 10 | MERS-CoV infection in humans is associated with a pro-inflammatory Th1 and Th17 cytokine profile | Cytokine | 2018 | 488 |
| 11 | IL-17 family: Cytokines, receptors and signaling | Cytokine | 2013 | 465 |
| 12 | Direct stimulation of cytokines (IL-1β, TNF-α, IL-6, IL-2, IFN-γ and GM-CSF) in whole blood. I. Comparison with isolated PBMC stimulation | Cytokine | 1992 | 451 |
| 13 | DIFFERENTIAL REGULATION OF PRO-INFLAMMATORY CYTOKINES DURING WOUND HEALING IN NORMAL AND GLUCOCORTICOID-TREATED MICE | Cytokine | 1996 | 443 |
| 14 | Interleukin-6 and its receptors: A highly regulated and dynamic system | Cytokine | 2014 | 443 |
| 15 | The interleukin (IL)-1 cytokine family – Balance between agonists and antagonists in inflammatory diseases | Cytokine | 2015 | 385 |
| 16 | HIGH ALTITUDE INCREASES CIRCULATING INTERLEUKIN-6, INTERLEUKIN-1 RECEPTOR ANTAGONIST AND C-REACTIVE PROTEIN | Cytokine | 2000 | 376 |
| 17 | Th1/Th2/Th17/Treg cytokine imbalance in systemic lupus erythematosus (SLE) patients: Correlation with disease activity | Cytokine | 2015 | 374 |
| 18 | Overview of interleukin-2 function, production and clinical applications | Cytokine | 2004 | 367 |
| 19 | IL-4 and IL-13 signaling in allergic airway disease | Cytokine | 2015 | 364 |
| 20 | Adiponectin expression in human epicardial adipose tissue in vivo is lower in patients with coronary artery disease | Cytokine | 2005 | 358 |
| 21 | AUTOCRINE AND PARACRINE REGULATION BY CYTOKINES AND GROWTH FACTORS IN MELANOMA | Cytokine | 2000 | 357 |
| 22 | Honey stimulates inflammatory cytokine production from monocytes | Cytokine | 2003 | 357 |
| 23 | COVID-19 cytokine storm: The anger of inflammation | Cytokine | 2020 | 357 |
| 24 | Isolation of an mRNA encoding a soluble form of the human interleukin-6 receptor | Cytokine | 1992 | 348 |
| 25 | Toll-like receptors: Activation, signalling and transcriptional modulation | Cytokine | 2015 | 344 |
| 26 | Innate immune response to viral infection | Cytokine | 2008 | 337 |
| 27 | Autophagy and cytokines | Cytokine | 2011 | 334 |
| 28 | Granulocyte colony-stimulating factor: Molecular mechanisms of action during steady state and ‘emergency’ hematopoiesis | Cytokine | 2008 | 331 |
| 29 | Induction of inflammatory cytokine release from cultured human monocytes by C-reactive protein | Cytokine | 1992 | 329 |
| 30 | Monocyte Chemoattractant Protein 1 (MCP-1) in obesity and diabetes | Cytokine | 2012 | 324 |
| 31 | Adiponectin, TNF-α and inflammatory cytokines and risk of type 2 diabetes: A systematic review and meta-analysis | Cytokine | 2016 | 321 |
| 32 | T helper 2 (Th2) cell differentiation, type 2 innate lymphoid cell (ILC2) development and regulation of interleukin-4 (IL-4) and IL-13 production | Cytokine | 2015 | 307 |
| 33 | The senescence-associated secretory phenotype and its regulation | Cytokine | 2019 | 306 |
| 34 | The hematopoietin receptor superfamily | Cytokine | 1993 | 303 |
| 35 | Signalling adaptors used by Toll-like receptors: An update | Cytokine | 2008 | 300 |
| 36 | An overview of IL-17 function and signaling | Cytokine | 2008 | 295 |
| 37 | Cytokines as a key component of cancer-related inflammation | Cytokine | 2008 | 292 |
| 38 | Interleukin (IL)-33 induces the release of pro-inflammatory mediators by mast cells | Cytokine | 2007 | 285 |
| 39 | Cytokines in psoriasis | Cytokine | 2015 | 281 |
| 40 | B cells responses and cytokine production are regulated by their immune microenvironment | Cytokine | 2015 | 277 |
| 41 | Elevation of circulating interleukin 6 after surgery: Factors influencing the serum level | Cytokine | 1994 | 275 |
| 42 | Gene modulation and immunoregulatory roles of Interferonγ | Cytokine | 2010 | 275 |
| 43 | Changes in plasma levels of inflammatory cytokines in response to paclitaxel chemotherapy | Cytokine | 2004 | 271 |
| 44 | TNF activity and T cells | Cytokine | 2018 | 270 |
| 45 | DIURNAL RHYTHMS OF PRO-INFLAMMATORY CYTOKINES: REGULATION BY PLASMA CORTISOL AND THERAPEUTIC IMPLICATIONS | Cytokine | 1998 | 267 |
| 46 | IL-17/Th17 targeting: On the road to prevent chronic destructive arthritis? | Cytokine | 2008 | 267 |
| 47 | FGF-19, A NOVEL FIBROBLAST GROWTH FACTOR WITH UNIQUE SPECIFICITY FOR FGFR4 | Cytokine | 1999 | 266 |
| 48 | TWEAKing tissue remodeling by a multifunctional cytokine: Role of TWEAK/Fn14 pathway in health and disease | Cytokine | 2007 | 263 |
| 49 | The CCAAT/enhancer (C/EBP) family of basic-leucine zipper (bZIP) transcription factors is a multifaceted highly-regulated system for gene regulation | Cytokine | 2011 | 262 |
| 50 | MOLECULAR CHARACTERIZATION OF THE HUMAN INTERLEUKIN (Il)-17 RECEPTOR | Cytokine | 1997 | 261 |
