| # | Title | Journal | Year | Citations |
|---|
| 1 | A Bayesian neural network method for adverse drug reaction signal generation | European Journal of Clinical Pharmacology | 1998 | 837 |
| 2 | Defective N-oxidation of sparteine in man: A new pharmacogenetic defect | European Journal of Clinical Pharmacology | 1979 | 653 |
| 3 | Safety, pharmacodynamics, and pharmacokinetics of BAY 59-7939—an oral, direct Factor Xa inhibitor—after multiple dosing in healthy male subjects | European Journal of Clinical Pharmacology | 2005 | 615 |
| 4 | The clinical pharmacology of 6-mercaptopurine | European Journal of Clinical Pharmacology | 1992 | 578 |
| 5 | Stereochemistry, a basis for sophisticated nonsense in pharmacokinetics and clinical pharmacology | European Journal of Clinical Pharmacology | 1984 | 576 |
| 6 | Pharmacokinetics and dosage adjustment in patients with hepatic dysfunction | European Journal of Clinical Pharmacology | 2008 | 518 |
| 7 | Pharmacokinetics of quercetin from quercetin aglycone and rutin in healthy volunteers | European Journal of Clinical Pharmacology | 2000 | 439 |
| 8 | Comparison of fixed interval and visual analogue scales for rating chronic pain | European Journal of Clinical Pharmacology | 1975 | 435 |
| 9 | Potentially inappropriate medications in the elderly: a French consensus panel list | European Journal of Clinical Pharmacology | 2007 | 411 |
| 10 | Pharmacokinetics and dosage adjustment in patients with renal dysfunction | European Journal of Clinical Pharmacology | 2009 | 392 |
| 11 | Pharmacogenetics of mephenytoin: A new drug hydroxylation polymorphism in man | European Journal of Clinical Pharmacology | 1984 | 376 |
| 12 | Hydroxylation polymorphisms of debrisoquine and mephenytoin in European populations | European Journal of Clinical Pharmacology | 1990 | 361 |
| 13 | Disposition of quercetin in man after single oral and intravenous doses | European Journal of Clinical Pharmacology | 1975 | 353 |
| 14 | Clinical pharmacology and pharmacogenetics of thiopurines | European Journal of Clinical Pharmacology | 2008 | 350 |
| 15 | The efficacy of ginseng. A systematic review of randomised clinical trials | European Journal of Clinical Pharmacology | 1999 | 347 |
| 16 | Determination of drug metabolizing enzymes in needle biopsies of human liver | European Journal of Clinical Pharmacology | 1972 | 338 |
| 17 | Hepatotoxicity from green tea: a review of the literature and two unpublished cases | European Journal of Clinical Pharmacology | 2009 | 334 |
| 18 | Vancomycin-induced nephrotoxicity: mechanism, incidence, risk factors and special populations. A literature review | European Journal of Clinical Pharmacology | 2012 | 333 |
| 19 | The EU(7)-PIM list: a list of potentially inappropriate medications for older people consented by experts from seven European countries | European Journal of Clinical Pharmacology | 2015 | 324 |
| 20 | The absolute bioavailability of caffeine in man | European Journal of Clinical Pharmacology | 1983 | 318 |
| 21 | Pharmacokinetics and organ distribution of intravenous and oral methylene blue | European Journal of Clinical Pharmacology | 2000 | 311 |
| 22 | Clinical significance of the sparteine/debrisoquine oxidation polymorphism | European Journal of Clinical Pharmacology | 1989 | 301 |
| 23 | Pharmacokinetics of metformin after intravenous and oral administration to man | European Journal of Clinical Pharmacology | 1979 | 297 |
| 24 | Pharmacokinetics of N-acetylcysteine in man | European Journal of Clinical Pharmacology | 1986 | 296 |
| 25 | Pharmacokinetics and bioavailability of reduced and oxidized N-acetylcysteine | European Journal of Clinical Pharmacology | 1988 | 295 |
| 26 | Positron emission tomography microdosing: a new concept with application in tracer and early clinical drug development | European Journal of Clinical Pharmacology | 2003 | 295 |
| 27 | Dose-dependent inhibition of CYP1A2, CYP2C19 and CYP2D6 by citalopram, fluoxetine, fluvoxamine and paroxetine | European Journal of Clinical Pharmacology | 1996 | 284 |
| 28 | Prevalence of potentially inappropriate prescribing in an acutely ill population of older patients admitted to six European hospitals | European Journal of Clinical Pharmacology | 2011 | 284 |
| 29 | Population pharmacokinetic analysis of infliximab in patients with ulcerative colitis | European Journal of Clinical Pharmacology | 2009 | 276 |
| 30 | Systematic review of anticholinergic risk scales in older adults | European Journal of Clinical Pharmacology | 2013 | 276 |
| 31 | Age differences in drug binding by plasma proteins: Studies on human foetuses, neonates and adults | European Journal of Clinical Pharmacology | 1971 | 270 |
| 32 | The pharmacokinetics of midazolam in man | European Journal of Clinical Pharmacology | 1981 | 266 |
| 33 | Proton pump inhibitors: an update of their clinical use and pharmacokinetics | European Journal of Clinical Pharmacology | 2008 | 266 |
| 34 | Delivery outcome after the use of antidepressants in early pregnancy | European Journal of Clinical Pharmacology | 1999 | 261 |
| 35 | Polypharmacy, length of hospital stay, and in-hospital mortality among elderly patients in internal medicine wards. The REPOSI study | European Journal of Clinical Pharmacology | 2011 | 255 |
| 36 | Hospital admissions due to adverse drug reactions in the elderly. A meta-analysis | European Journal of Clinical Pharmacology | 2017 | 253 |
| 37 | The pharmacodynamics and metabolism of propranolol in man | European Journal of Clinical Pharmacology | 1970 | 250 |
| 38 | Pharmacokinetics of paracetamol (acetaminophen) after intravenous and oral administration | European Journal of Clinical Pharmacology | 1977 | 250 |
| 39 | The systemic availability of oral glutathione | European Journal of Clinical Pharmacology | 1992 | 250 |
| 40 | The area under the plasma concentration-time curve for oral midazolam is 400-fold larger during treatment with itraconazole than with rifampicin | European Journal of Clinical Pharmacology | 1998 | 246 |
| 41 | Complexes of metals other than platinum as antitumour agents | European Journal of Clinical Pharmacology | 1994 | 243 |
| 42 | Corticosteroid-induced bone loss. A longitudinal study of alternate day therapy in patients with bronchial asthma using quantitative computed tomography | European Journal of Clinical Pharmacology | 1983 | 239 |
| 43 | Clinical pharmacology of thalidomide | European Journal of Clinical Pharmacology | 2001 | 238 |
| 44 | The effectiveness of topically applied capsaicin | European Journal of Clinical Pharmacology | 1994 | 237 |
| 45 | QT-interval prolongation by non-cardiac drugs: lessons to be learned from recent experience | European Journal of Clinical Pharmacology | 2000 | 236 |
| 46 | Evidence of clinical efficacy of homeopathy | European Journal of Clinical Pharmacology | 2000 | 236 |
| 47 | Admissions caused by adverse drug events to internal medicine and emergency departments in hospitals: a longitudinal population-based study | European Journal of Clinical Pharmacology | 2002 | 236 |
| 48 | Macrolides: from in vitro anti-inflammatory and immunomodulatory properties to clinical practice in respiratory diseases | European Journal of Clinical Pharmacology | 2012 | 235 |
| 49 | The pharmacokinetics of midazolam in paediatric patients | European Journal of Clinical Pharmacology | 1989 | 230 |
| 50 | Agranulocytosis and other blood dyscrasias associated with dipyrone (metamizole) | European Journal of Clinical Pharmacology | 2002 | 226 |
