# | Title | Journal | Year | Citations |
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1 | Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review | Journal of Controlled Release | 2000 | 5,797 |
2 | Doxil® — The first FDA-approved nano-drug: Lessons learned | Journal of Controlled Release | 2012 | 3,356 |
3 | A simple equation for description of solute release II. Fickian and anomalous release from swellable devices | Journal of Controlled Release | 1987 | 3,239 |
4 | A simple equation for description of solute release I. Fickian and non-fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs | Journal of Controlled Release | 1987 | 3,070 |
5 | Biodegradable polymeric nanoparticles as drug delivery devices | Journal of Controlled Release | 2001 | 3,026 |
6 | PLGA-based nanoparticles: An overview of biomedical applications | Journal of Controlled Release | 2012 | 2,692 |
7 | DLS and zeta potential – What they are and what they are not? | Journal of Controlled Release | 2016 | 2,428 |
8 | To exploit the tumor microenvironment: Passive and active tumor targeting of nanocarriers for anti-cancer drug delivery | Journal of Controlled Release | 2010 | 2,256 |
9 | Recent advances on chitosan-based micro- and nanoparticles in drug delivery | Journal of Controlled Release | 2004 | 2,181 |
10 | A review of stimuli-responsive nanocarriers for drug and gene delivery | Journal of Controlled Release | 2008 | 1,981 |
11 | Albumin as a drug carrier: Design of prodrugs, drug conjugates and nanoparticles | Journal of Controlled Release | 2008 | 1,835 |
12 | Toxicity of cationic lipids and cationic polymers in gene delivery | Journal of Controlled Release | 2006 | 1,832 |
13 | Endocytosis of nanomedicines | Journal of Controlled Release | 2010 | 1,755 |
14 | Polyionic hydrocolloids for the intestinal delivery of protein drugs: Alginate and chitosan — a review | Journal of Controlled Release | 2006 | 1,647 |
15 | Structure and design of polymeric surfactant-based drug delivery systems | Journal of Controlled Release | 2001 | 1,588 |
16 | Targeted drug delivery to tumors: Myths, reality and possibility | Journal of Controlled Release | 2011 | 1,580 |
17 | “Nanoantibiotics”: A new paradigm for treating infectious diseases using nanomaterials in the antibiotics resistant era | Journal of Controlled Release | 2011 | 1,502 |
18 | Nanomedicine in cancer therapy: Challenges, opportunities, and clinical applications | Journal of Controlled Release | 2015 | 1,477 |
19 | On the importance and mechanisms of burst release in matrix-controlled drug delivery systems | Journal of Controlled Release | 2001 | 1,431 |
20 | Exosomes as drug delivery vehicles for Parkinson's disease therapy | Journal of Controlled Release | 2015 | 1,363 |
21 | Pluronic® block copolymers as novel polymer therapeutics for drug and gene delivery | Journal of Controlled Release | 2002 | 1,310 |
22 | Block copolymer micelles: preparation, characterization and application in drug delivery | Journal of Controlled Release | 2005 | 1,303 |
23 | Endosomal escape pathways for delivery of biologicals | Journal of Controlled Release | 2011 | 1,278 |
24 | Albumin-based nanoparticles as potential controlled release drug delivery systems | Journal of Controlled Release | 2012 | 1,198 |
25 | Release of tetracycline hydrochloride from electrospun poly(ethylene-co-vinylacetate), poly(lactic acid), and a blend | Journal of Controlled Release | 2002 | 1,191 |
26 | Glutathione-responsive nano-vehicles as a promising platform for targeted intracellular drug and gene delivery | Journal of Controlled Release | 2011 | 1,187 |
27 | Dendrimers: | Journal of Controlled Release | 2000 | 1,151 |
28 | Nanoparticles as potential oral delivery systems of proteins and vaccines: A mechanistic approach | Journal of Controlled Release | 2006 | 1,144 |
29 | Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency | Journal of Controlled Release | 2001 | 1,140 |
30 | Drug targeting to tumors: Principles, pitfalls and (pre-) clinical progress | Journal of Controlled Release | 2012 | 1,131 |
31 | Poly(ethylenimine) and its role in gene delivery | Journal of Controlled Release | 1999 | 1,130 |
32 | PEG-modified gold nanorods with a stealth character for in vivo applications | Journal of Controlled Release | 2006 | 1,098 |
33 | Pluronic block copolymers: Evolution of drug delivery concept from inert nanocarriers to biological response modifiers | Journal of Controlled Release | 2008 | 1,091 |
34 | Graphene-based nanomaterials for drug delivery and tissue engineering | Journal of Controlled Release | 2014 | 1,083 |
35 | Particle shape: A new design parameter for micro- and nanoscale drug delivery carriers | Journal of Controlled Release | 2007 | 1,072 |
36 | Ethosomes — novel vesicular carriers for enhanced delivery: characterization and skin penetration properties | Journal of Controlled Release | 2000 | 1,033 |
37 | Nanoparticle-mediated brain drug delivery: Overcoming blood–brain barrier to treat neurodegenerative diseases | Journal of Controlled Release | 2016 | 1,018 |
38 | Electrospinning of polymeric nanofibers for drug delivery applications | Journal of Controlled Release | 2014 | 995 |
39 | Design and production of nanoparticles formulated from nano-emulsion templates—A review | Journal of Controlled Release | 2008 | 988 |
40 | Nano/micro technologies for delivering macromolecular therapeutics using poly(d,l-lactide-co-glycolide) and its derivatives | Journal of Controlled Release | 2008 | 940 |
41 | To exploit the tumor microenvironment: Since the EPR effect fails in the clinic, what is the future of nanomedicine? | Journal of Controlled Release | 2016 | 934 |
42 | Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy | Journal of Controlled Release | 2012 | 929 |
43 | Gelatin as a delivery vehicle for the controlled release of bioactive molecules | Journal of Controlled Release | 2005 | 928 |
44 | Nasal drug delivery—possibilities, problems and solutions | Journal of Controlled Release | 2003 | 877 |
45 | Nanoparticle–liver interactions: Cellular uptake and hepatobiliary elimination | Journal of Controlled Release | 2016 | 869 |
46 | PLGA nanoparticles prepared by nanoprecipitation: drug loading and release studies of a water soluble drug | Journal of Controlled Release | 1999 | 868 |
47 | Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS | Journal of Controlled Release | 2001 | 861 |
48 | Polysaccharide hydrogels for modified release formulations | Journal of Controlled Release | 2007 | 855 |
49 | Residual polyvinyl alcohol associated with poly (d,l-lactide-co-glycolide) nanoparticles affects their physical properties and cellular uptake | Journal of Controlled Release | 2002 | 846 |
50 | A novel pH-sensitive hydrogel composed of N,O-carboxymethyl chitosan and alginate cross-linked by genipin for protein drug delivery | Journal of Controlled Release | 2004 | 825 |