# | Title | Journal | Year | Citations |
---|
1 | The biology of VEGF and its receptors | Nature Medicine | 2003 | 8,501 |
2 | Angiogenesis in cancer, vascular, rheumatoid and other disease | Nature Medicine | 1995 | 7,257 |
3 | Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell | Nature Medicine | 1997 | 6,150 |
4 | Microenvironmental regulation of tumor progression and metastasis | Nature Medicine | 2013 | 5,730 |
5 | Neurogenesis in the adult human hippocampus | Nature Medicine | 1998 | 5,606 |
6 | Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival | Nature Medicine | 2004 | 4,442 |
7 | The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity | Nature Medicine | 2001 | 4,370 |
8 | Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion | Nature Medicine | 2002 | 4,217 |
9 | The proximal origin of SARS-CoV-2 | Nature Medicine | 2020 | 3,871 |
10 | Temporal dynamics in viral shedding and transmissibility of COVID-19 | Nature Medicine | 2020 | 3,838 |
11 | Angiogenesis in health and disease | Nature Medicine | 2003 | 3,726 |
12 | Mechanisms of angiogenesis and arteriogenesis | Nature Medicine | 2000 | 3,709 |
13 | Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase | Nature Medicine | 2002 | 3,692 |
14 | Cancer genes and the pathways they control | Nature Medicine | 2004 | 3,689 |
15 | Tissue microarrays for high-throughput molecular profiling of tumor specimens | Nature Medicine | 1998 | 3,661 |
16 | The consensus molecular subtypes of colorectal cancer | Nature Medicine | 2015 | 3,596 |
17 | Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects | Nature Medicine | 1995 | 3,427 |
18 | Understanding the tumor immune microenvironment (TIME) for effective therapy | Nature Medicine | 2018 | 3,421 |
19 | Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr–Abl positive cells | Nature Medicine | 1996 | 3,357 |
20 | Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis | Nature Medicine | 2013 | 3,355 |
21 | Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory | Nature Medicine | 2008 | 3,225 |
22 | Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection | Nature Medicine | 2021 | 3,133 |
23 | Antibacterial resistance worldwide: causes, challenges and responses | Nature Medicine | 2004 | 3,111 |
24 | Microbial translocation is a cause of systemic immune activation in chronic HIV infection | Nature Medicine | 2006 | 3,107 |
25 | Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET | Nature Medicine | 2012 | 3,098 |
26 | Post-acute COVID-19 syndrome | Nature Medicine | 2021 | 3,051 |
27 | A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus–induced lung injury | Nature Medicine | 2005 | 2,986 |
28 | A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma | Nature Medicine | 1997 | 2,939 |
29 | High-performance medicine: the convergence of human and artificial intelligence | Nature Medicine | 2019 | 2,938 |
30 | Mitochondrial control of cell death | Nature Medicine | 2000 | 2,937 |
31 | Protein aggregation and neurodegenerative disease | Nature Medicine | 2004 | 2,792 |
32 | Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response | Nature Medicine | 2018 | 2,791 |
33 | Cancer immunotherapy: moving beyond current vaccines | Nature Medicine | 2004 | 2,708 |
34 | Vaccination of melanoma patients with peptide- or tumorlysate-pulsed dendritic cells | Nature Medicine | 1998 | 2,689 |
35 | Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy | Nature Medicine | 2007 | 2,657 |
36 | Neuronal replacement from endogenous precursors in the adult brain after stroke | Nature Medicine | 2002 | 2,613 |
37 | Mechanisms of fibrosis: therapeutic translation for fibrotic disease | Nature Medicine | 2012 | 2,601 |
38 | Metabolite profiles and the risk of developing diabetes | Nature Medicine | 2011 | 2,586 |
39 | Calreticulin exposure dictates the immunogenicity of cancer cell death | Nature Medicine | 2007 | 2,580 |
40 | Production of infectious hepatitis C virus in tissue culture from a cloned viral genome | Nature Medicine | 2005 | 2,561 |
41 | Secreted amyloid β–protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease | Nature Medicine | 1996 | 2,545 |
42 | Antibody responses to SARS-CoV-2 in patients with COVID-19 | Nature Medicine | 2020 | 2,542 |
43 | Ischemia and reperfusion—from mechanism to translation | Nature Medicine | 2011 | 2,524 |
44 | Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets | Nature Medicine | 2000 | 2,515 |
45 | Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway | Nature Medicine | 2000 | 2,506 |
46 | The prognostic landscape of genes and infiltrating immune cells across human cancers | Nature Medicine | 2015 | 2,505 |
47 | Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections | Nature Medicine | 2020 | 2,499 |
48 | Inflammasomes: mechanism of action, role in disease, and therapeutics | Nature Medicine | 2015 | 2,476 |
49 | Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients | Nature Medicine | 2017 | 2,473 |
50 | ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets | Nature Medicine | 2013 | 2,426 |