| # | Title | Journal | Year | Citations |
|---|
| 1 | Hypoxic enhancement of exosome release by breast cancer cells | BMC Cancer | 2012 | 821 |
| 2 | M1 and M2 macrophages derived from THP-1 cells differentially modulate the response of cancer cells to etoposide | BMC Cancer | 2015 | 641 |
| 3 | Cardiotoxicity of anthracycline agents for the treatment of cancer: Systematic review and meta-analysis of randomised controlled trials | BMC Cancer | 2010 | 560 |
| 4 | Colorectal cancer liver metastases – a population-based study on incidence, management and survival | BMC Cancer | 2018 | 532 |
| 5 | The presence of tumor associated macrophages in tumor stroma as a prognostic marker for breast cancer patients | BMC Cancer | 2012 | 531 |
| 6 | Interaction and uptake of exosomes by ovarian cancer cells | BMC Cancer | 2011 | 513 |
| 7 | Prolyl-4-hydroxylase α subunit 2 promotes breast cancer progression and metastasis by regulating collagen deposition | BMC Cancer | 2014 | 504 |
| 8 | Noninvasive detection of lung cancer by analysis of exhaled breath | BMC Cancer | 2009 | 472 |
| 9 | Circulating tumour cells escape from EpCAM-based detection due to epithelial-to-mesenchymal transition | BMC Cancer | 2012 | 464 |
| 10 | An electronic application for rapidly calculating Charlson comorbidity score | BMC Cancer | 2004 | 440 |
| 11 | Imagable 4T1 model for the study of late stage breast cancer | BMC Cancer | 2008 | 427 |
| 12 | Gene expression profiles of prostate cancer reveal involvement of multiple molecular pathways in the metastatic process | BMC Cancer | 2007 | 421 |
| 13 | High Oct4 expression: implications in the pathogenesis of neuroblastic tumours | BMC Cancer | 2019 | 420 |
| 14 | The claudin gene family: expression in normal and neoplastic tissues | BMC Cancer | 2006 | 418 |
| 15 | PROGgeneV2: enhancements on the existing database | BMC Cancer | 2014 | 417 |
| 16 | Worldwide trends in mortality from biliary tract malignancies | BMC Cancer | 2002 | 413 |
| 17 | Type 2 diabetes increases and metformin reduces total, colorectal, liver and pancreatic cancer incidences in Taiwanese: a representative population prospective cohort study of 800,000 individuals | BMC Cancer | 2011 | 398 |
| 18 | Long non-coding RNA MEG3 inhibits NSCLC cells proliferation and induces apoptosis by affecting p53 expression | BMC Cancer | 2013 | 389 |
| 19 | Meta-analysis of randomized trials: evaluation of benefit from gemcitabine-based combination chemotherapy applied in advanced pancreatic cancer | BMC Cancer | 2008 | 377 |
| 20 | Global and regional estimates of cancer mortality and incidence by site: II. results for the global burden of disease 2000 | BMC Cancer | 2002 | 365 |
| 21 | The M1 form of tumor-associated macrophages in non-small cell lung cancer is positively associated with survival time | BMC Cancer | 2010 | 365 |
| 22 | Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres | BMC Cancer | 2008 | 355 |
| 23 | The long non-coding RNA HOTAIR indicates a poor prognosis and promotes metastasis in non-small cell lung cancer | BMC Cancer | 2013 | 351 |
| 24 | Depression and anxiety among people living with and beyond cancer: a growing clinical and research priority | BMC Cancer | 2019 | 350 |
| 25 | Cytochrome P450 CYP1A1: wider roles in cancer progression and prevention | BMC Cancer | 2009 | 342 |
| 26 | Novel markers for differentiation of lobular and ductal invasive breast carcinomas by laser microdissection and microarray analysis | BMC Cancer | 2007 | 341 |
| 27 | MicroRNA-221 and microRNA-222 regulate gastric carcinoma cell proliferation and radioresistance by targeting PTEN | BMC Cancer | 2010 | 339 |
| 28 | Feasibility and acceptability of combining cognitive behavioural therapy techniques with swallowing therapy in head and neck cancer dysphagia | BMC Cancer | 2018 | 331 |
| 29 | Follow-up of patients with curatively resected colorectal cancer: a practice guideline | BMC Cancer | 2003 | 328 |
| 30 | EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer | BMC Cancer | 2012 | 325 |
| 31 | Use of immunohistochemical markers can refine prognosis in triple negative breast cancer | BMC Cancer | 2007 | 316 |
| 32 | Adjuvant trastuzumab in the treatment of her-2-positive early breast cancer: a meta-analysis of published randomized trials | BMC Cancer | 2007 | 316 |
| 33 | Expression of matrix metalloproteinases (MMPs) in primary human breast cancer and breast cancer cell lines: New findings and review of the literature | BMC Cancer | 2009 | 314 |
| 34 | Radioactive 125I seeds inhibit cell growth and epithelial-mesenchymal transition in human glioblastoma multiforme via a ROS-mediated signaling pathway | BMC Cancer | 2015 | 314 |
| 35 | 3D pancreatic carcinoma spheroids induce a matrix-rich, chemoresistant phenotype offering a better model for drug testing | BMC Cancer | 2013 | 301 |
| 36 | Activation of β-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters | BMC Cancer | 2011 | 298 |
| 37 | Elevated cyclin B2 expression in invasive breast carcinoma is associated with unfavorable clinical outcome | BMC Cancer | 2013 | 293 |
| 38 | Long-term safety and efficacy of vismodegib in patients with advanced basal cell carcinoma: final update of the pivotal ERIVANCE BCC study | BMC Cancer | 2017 | 291 |
| 39 | Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states | BMC Cancer | 2009 | 281 |
| 40 | Clinical presentation, histology, and prognoses of malignant melanoma in ethnic Chinese: A study of 522 consecutive cases | BMC Cancer | 2011 | 276 |
| 41 | Organ Preservation in Rectal Adenocarcinoma: a phase II randomized controlled trial evaluating 3-year disease-free survival in patients with locally advanced rectal cancer treated with chemoradiation plus induction or consolidation chemotherapy, and total mesorectal excision or nonoperative management | BMC Cancer | 2015 | 276 |
| 42 | Decreased expression of long noncoding RNA GAS5 indicates a poor prognosis and promotes cell proliferation in gastric cancer | BMC Cancer | 2014 | 273 |
| 43 | Development of primary human pancreatic cancer organoids, matched stromal and immune cells and 3D tumor microenvironment models | BMC Cancer | 2018 | 271 |
| 44 | Solar ultraviolet-B exposure and cancer incidence and mortality in the United States, 1993–2002 | BMC Cancer | 2006 | 269 |
| 45 | Correlation of microarray-based breast cancer molecular subtypes and clinical outcomes: implications for treatment optimization | BMC Cancer | 2011 | 269 |
| 46 | Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells | BMC Cancer | 2010 | 267 |
| 47 | Secretion of extracellular hsp90α via exosomes increases cancer cell motility: a role for plasminogen activation | BMC Cancer | 2010 | 264 |
| 48 | A novel Bcl-2 inhibitor, BM-1197, induces apoptosis in malignant lymphoma cells through the endogenous apoptotic pathway | BMC Cancer | 2020 | 264 |
| 49 | Physical and psychosocial benefits of yoga in cancer patients and survivors, a systematic review and meta-analysis of randomized controlled trials | BMC Cancer | 2012 | 263 |
| 50 | Ki67, chemotherapy response, and prognosis in breast cancer patients receiving neoadjuvant treatment | BMC Cancer | 2011 | 260 |
