| # | Title | Journal | Year | Citations |
|---|
| 1 | The tail suspension test: A new method for screening antidepressants in mice | Psychopharmacology | 1985 | 2,834 |
| 2 | The use of a plus-maze to measure anxiety in the mouse | Psychopharmacology | 1987 | 2,130 |
| 3 | The debate over dopamine’s role in reward: the case for incentive salience | Psychopharmacology | 2007 | 1,919 |
| 4 | Varieties of impulsivity | Psychopharmacology | 1999 | 1,643 |
| 5 | Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant | Psychopharmacology | 1987 | 1,630 |
| 6 | Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation | Psychopharmacology | 1997 | 1,607 |
| 7 | Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies | Psychopharmacology | 2001 | 1,562 |
| 8 | The reinstatement model of drug relapse: history, methodology and major findings | Psychopharmacology | 2003 | 1,484 |
| 9 | Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review | Psychopharmacology | 2001 | 1,404 |
| 10 | Impulsivity resulting from frontostriatal dysfunction in drug abuse: implications for the control of behavior by reward-related stimuli | Psychopharmacology | 1999 | 1,358 |
| 11 | How does stress increase risk of drug abuse and relapse? | Psychopharmacology | 2001 | 1,290 |
| 12 | Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies | Psychopharmacology | 1997 | 1,283 |
| 13 | Alterations in dopaminergic and glutamatergic transmission in the induction and expression of behavioral sensitization: a critical review of preclinical studies | Psychopharmacology | 2000 | 1,251 |
| 14 | Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants | Psychopharmacology | 1995 | 1,239 |
| 15 | The validity of animal models of depression | Psychopharmacology | 1984 | 1,197 |
| 16 | The 5-choice serial reaction time task: behavioural pharmacology and functional neurochemistry | Psychopharmacology | 2002 | 1,155 |
| 17 | Impulsivity and cigarette smoking: delay discounting in current, never, and ex-smokers | Psychopharmacology | 1999 | 1,148 |
| 18 | Comprehensive observational assessment: Ia. A systematic, quantitative procedure for assessing the behavioral and physiologic state of the mouse | Psychopharmacology | 1968 | 1,140 |
| 19 | Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance | Psychopharmacology | 2006 | 1,113 |
| 20 | Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding | Psychopharmacology | 1996 | 1,065 |
| 21 | Conditioned place preference: what does it add to our preclinical understanding of drug reward? | Psychopharmacology | 2000 | 1,057 |
| 22 | Affective neuroscience of pleasure: reward in humans and animals | Psychopharmacology | 2008 | 1,011 |
| 23 | Effects of early life stress on cognitive and affective function: an integrated review of human literature | Psychopharmacology | 2011 | 995 |
| 24 | Neural circuit regulation of prepulse inhibition of startle in the rat: current knowledge and future challenges | Psychopharmacology | 2001 | 969 |
| 25 | Tonic dopamine: opportunity costs and the control of response vigor | Psychopharmacology | 2007 | 969 |
| 26 | Mode of action of apomorphine and dexamphetamine on gnawing compulsion in rats | Psychopharmacology | 1967 | 924 |
| 27 | Effort-related functions of nucleus accumbens dopamine and associated forebrain circuits | Psychopharmacology | 2007 | 913 |
| 28 | Reinstatement of cocaine-reinforced responding in the rat | Psychopharmacology | 1981 | 900 |
| 29 | Is the forced swimming test a suitable model for revealing antidepressant activity? | Psychopharmacology | 1988 | 886 |
| 30 | Delineation of two drug-responsive anxiety syndromes | Psychopharmacology | 1964 | 866 |
| 31 | A simple and reliable conflict procedure for testing anti-anxiety agents | Psychopharmacology | 1971 | 789 |
| 32 | Forced swimming test in mice: a review of antidepressant activity | Psychopharmacology | 2005 | 788 |
| 33 | Delayed reward discounting and addictive behavior: a meta-analysis | Psychopharmacology | 2011 | 782 |
| 34 | Self-administration of psychoactive substances by the monkey | Psychopharmacology | 1969 | 781 |
| 35 | Measures of impulsivity in cigarette smokers and non-smokers | Psychopharmacology | 1999 | 777 |
| 36 | The effects of meprobamate, barbiturates, d-amphetamine and promazine on experimentally induced conflict in the rat | Psychopharmacology | 1960 | 776 |
| 37 | The mesolimbic dopaminergic system is implicated in the reinforcing effects of nicotine | Psychopharmacology | 1992 | 767 |
| 38 | Induction of physical dependence upon ethanol and the associated behavioral changes in rats | Psychopharmacology | 1975 | 718 |
| 39 | Endogenous opioid systems and alcohol addiction | Psychopharmacology | 1997 | 715 |
| 40 | Nicotinic effects on cognitive function: behavioral characterization, pharmacological specification, and anatomic localization | Psychopharmacology | 2006 | 711 |
| 41 | Guidelines on nicotine dose selection for in vivo research | Psychopharmacology | 2007 | 694 |
| 42 | Tryptophan depletion causes a rapid lowering of mood in normal males | Psychopharmacology | 1985 | 678 |
| 43 | Ionotropic and metabotropic glutamate receptor structure and pharmacology | Psychopharmacology | 2005 | 663 |
| 44 | The role of impulsive behavior in drug abuse | Psychopharmacology | 2008 | 654 |
| 45 | Nicotinic acetylcholine involvement in cognitive function in animals | Psychopharmacology | 1998 | 646 |
| 46 | Delay discounting of money and alcohol in actively using alcoholics, currently abstinent alcoholics, and controls | Psychopharmacology | 2001 | 646 |
| 47 | Psilocybin occasioned mystical-type experiences: immediate and persisting dose-related effects | Psychopharmacology | 2011 | 638 |
| 48 | l-Dopa withdrawal in Parkinson's disease selectively impairs cognitive performance in tests sensitive to frontal lobe dysfunction | Psychopharmacology | 1992 | 631 |
| 49 | Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats | Psychopharmacology | 1984 | 621 |
| 50 | Behavioural and pharmacological characterisation of the elevated “zero-maze” as an animal model of anxiety | Psychopharmacology | 1994 | 611 |
