| # | Title | Journal | Year | Citations |
|---|
| 1 | Activators and target genes of Rel/NF-κB transcription factors | Oncogene | 1999 | 3,586 |
| 2 | Cisplatin: mode of cytotoxic action and molecular basis of resistance | Oncogene | 2003 | 2,838 |
| 3 | MAP kinase signalling pathways in cancer | Oncogene | 2007 | 2,473 |
| 4 | Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer | Oncogene | 2007 | 2,421 |
| 5 | EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer | Oncogene | 2010 | 2,263 |
| 6 | Molecular mechanisms of cisplatin resistance | Oncogene | 2012 | 2,058 |
| 7 | The p53 pathway: positive and negative feedback loops | Oncogene | 2005 | 2,056 |
| 8 | MALAT-1, a novel noncoding RNA, and thymosin β4 predict metastasis and survival in early-stage non-small cell lung cancer | Oncogene | 2003 | 1,986 |
| 9 | Wnt signaling in cancer | Oncogene | 2017 | 1,975 |
| 10 | Introduction to NF-κB: players, pathways, perspectives | Oncogene | 2006 | 1,948 |
| 11 | STATs in oncogenesis | Oncogene | 2000 | 1,944 |
| 12 | Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy | Oncogene | 2006 | 1,914 |
| 13 | The tumor microenvironment and its role in promoting tumor growth | Oncogene | 2008 | 1,869 |
| 14 | The Bcl-2 apoptotic switch in cancer development and therapy | Oncogene | 2007 | 1,847 |
| 15 | MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer | Oncogene | 2008 | 1,719 |
| 16 | Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo | Oncogene | 1994 | 1,667 |
| 17 | PI3K pathway alterations in cancer: variations on a theme | Oncogene | 2008 | 1,621 |
| 18 | Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics | Oncogene | 2010 | 1,506 |
| 19 | TGF-β and epithelial-to-mesenchymal transitions | Oncogene | 2005 | 1,491 |
| 20 | AP-1 in cell proliferation and survival | Oncogene | 2001 | 1,485 |
| 21 | miR-21-mediated tumor growth | Oncogene | 2007 | 1,459 |
| 22 | DNA methylation in cancer: too much, but also too little | Oncogene | 2002 | 1,390 |
| 23 | Histone deacetylase inhibitors: molecular mechanisms of action | Oncogene | 2007 | 1,379 |
| 24 | Regulation of the G2/M transition by p53 | Oncogene | 2001 | 1,366 |
| 25 | Mitogen-activated protein kinases in apoptosis regulation | Oncogene | 2004 | 1,361 |
| 26 | The Bcl-2 family: roles in cell survival and oncogenesis | Oncogene | 2003 | 1,342 |
| 27 | Autophagy as a cell death and tumor suppressor mechanism | Oncogene | 2004 | 1,306 |
| 28 | The role of cyclooxygenases in inflammation, cancer, and development | Oncogene | 1999 | 1,289 |
| 29 | Glycolysis inhibition for anticancer treatment | Oncogene | 2006 | 1,278 |
| 30 | BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models | Oncogene | 2008 | 1,272 |
| 31 | JNK signaling in apoptosis | Oncogene | 2008 | 1,259 |
| 32 | Control of apoptosis by p53 | Oncogene | 2003 | 1,256 |
| 33 | The EGF receptor family as targets for cancer therapy | Oncogene | 2000 | 1,251 |
| 34 | Differential regulation and properties of MAPKs | Oncogene | 2007 | 1,246 |
| 35 | 5-Azacytidine and 5-aza-2′-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy | Oncogene | 2002 | 1,239 |
| 36 | LncRNA-mediated regulation of cell signaling in cancer | Oncogene | 2017 | 1,221 |
| 37 | Lysosomal membrane permeabilization in cell death | Oncogene | 2008 | 1,192 |
| 38 | Perturbations of the AKT signaling pathway in human cancer | Oncogene | 2005 | 1,184 |
| 39 | Control of apoptosis by Rel/NF-κB transcription factors | Oncogene | 1999 | 1,135 |
| 40 | FOXO transcription factors at the interface between longevity and tumor suppression | Oncogene | 2005 | 1,135 |
| 41 | Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression | Oncogene | 2004 | 1,124 |
| 42 | The role of STATs in transcriptional control and their impact on cellular function | Oncogene | 2000 | 1,103 |
| 43 | CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future | Oncogene | 2002 | 1,103 |
| 44 | The role of glutathione-S-transferase in anti-cancer drug resistance | Oncogene | 2003 | 1,103 |
| 45 | Circular RNAs in cancer: opportunities and challenges in the field | Oncogene | 2018 | 1,102 |
| 46 | Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues | Oncogene | 2006 | 1,088 |
| 47 | Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors | Oncogene | 2000 | 1,081 |
| 48 | The FoxO code | Oncogene | 2008 | 1,079 |
| 49 | How NF-κB is activated: the role of the IκB kinase (IKK) complex | Oncogene | 1999 | 1,078 |
| 50 | Epithelial–mesenchymal transition in development and cancer: role of phosphatidylinositol 3′ kinase/AKT pathways | Oncogene | 2005 | 1,078 |
