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Top Articles

#TitleJournalYearCitations
1Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.Molecular and Cellular Biology19829,217
2High-efficiency transformation of mammalian cells by plasmid DNA.Molecular and Cellular Biology19875,785
3Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cellsMolecular and Cellular Biology19824,919
4Activation of Vascular Endothelial Growth Factor Gene Transcription by Hypoxia-Inducible Factor 1Molecular and Cellular Biology19963,560
5Correlation between Protein and mRNA Abundance in YeastMolecular and Cellular Biology19993,521
6Firefly luciferase gene: structure and expression in mammalian cells.Molecular and Cellular Biology19873,275
7Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.Molecular and Cellular Biology19852,481
8High-Efficiency Transformation of Mammalian Cells by Plasmid DNAMolecular and Cellular Biology19872,479
9Analysis of Fractalkine Receptor CX 3 CR1 Function by Targeted Deletion and Green Fluorescent Protein Reporter Gene InsertionMolecular and Cellular Biology20002,319
10A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation.Molecular and Cellular Biology19922,242
11Oxidative Stress Sensor Keap1 Functions as an Adaptor for Cul3-Based E3 Ligase To Regulate Proteasomal Degradation of Nrf2Molecular and Cellular Biology20041,878
12Transposable Elements: Targets for Early Nutritional Effects on Epigenetic Gene RegulationMolecular and Cellular Biology20031,874
13XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein ResponseMolecular and Cellular Biology20031,796
14Gadd153 Sensitizes Cells to Endoplasmic Reticulum Stress by Down-Regulating Bcl2 and Perturbing the Cellular Redox StateMolecular and Cellular Biology20011,678
15Autophagy Is Activated for Cell Survival after Endoplasmic ReticulumStressMolecular and Cellular Biology20061,627
16CTLA-4 and PD-1 Receptors Inhibit T-Cell Activation by Distinct MechanismsMolecular and Cellular Biology20051,609
17Targeted Disruption of the α Isoform of the Peroxisome Proliferator-Activated Receptor Gene in Mice Results in Abolishment of the Pleiotropic Effects of Peroxisome ProliferatorsMolecular and Cellular Biology19951,585
18Helix-Loop-Helix Proteins: Regulators of Transcription in Eucaryotic OrganismsMolecular and Cellular Biology20001,573
19Inhibition of Macroautophagy Triggers ApoptosisMolecular and Cellular Biology20051,533
20c-Myc Target Genes Involved in Cell Growth, Apoptosis, and MetabolismMolecular and Cellular Biology19991,501
21Wnt/β-Catenin/Tcf Signaling Induces the Transcription of Axin2, a Negative Regulator of the Signaling PathwayMolecular and Cellular Biology20021,498
22Mitogen-Activated Protein Kinases: Specific Messages from Ubiquitous MessengersMolecular and Cellular Biology19991,490
23Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection.Molecular and Cellular Biology19901,474
24Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production.Molecular and Cellular Biology19861,449
25SR alpha promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat.Molecular and Cellular Biology19881,435
26High-efficiency cloning of full-length cDNA.Molecular and Cellular Biology19821,371
27Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease.Molecular and Cellular Biology19921,360
28Firefly Luciferase Gene: Structure and Expression in Mammalian CellsMolecular and Cellular Biology19871,330
29Activation of interleukin-6 gene expression through the NF-kappa B transcription factor.Molecular and Cellular Biology19901,267
30NF-κB Controls Cell Growth and Differentiation through Transcriptional Regulation of Cyclin D1Molecular and Cellular Biology19991,242
31Isolation and characterization of full-length cDNA clones for human alpha-, beta-, and gamma-actin mRNAs: skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently removed.Molecular and Cellular Biology19831,241
32Distinct Cysteine Residues in Keap1 Are Required for Keap1-Dependent Ubiquitination of Nrf2 and for Stabilization of Nrf2 by Chemopreventive Agents and Oxidative StressMolecular and Cellular Biology20031,241
33Differential Roles of Hypoxia-Inducible Factor 1α (HIF-1α) and HIF-2α in Hypoxic Gene RegulationMolecular and Cellular Biology20031,234
34Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 DomainsMolecular and Cellular Biology20091,228
35MKK3- and MKK6-Regulated Gene Expression Is Mediated by the p38 Mitogen-Activated Protein Kinase Signal Transduction PathwayMolecular and Cellular Biology19961,223
36Identification and Characterization of a Family of Mammalian Methyl-CpG Binding ProteinsMolecular and Cellular Biology19981,216
37HER2 (neu) Signaling Increases the Rate of Hypoxia-Inducible Factor 1α (HIF-1α) Synthesis: Novel Mechanism for HIF-1-Mediated Vascular Endothelial Growth Factor ExpressionMolecular and Cellular Biology20011,176
38Increased Energy Expenditure, Decreased Adiposity, and Tissue-Specific Insulin Sensitivity in Protein-Tyrosine Phosphatase 1B-Deficient MiceMolecular and Cellular Biology20001,150
39Isolation of Monoclonal Antibodies Specific for Human c-myc Proto-Oncogene ProductMolecular and Cellular Biology19851,131
40Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src.Molecular and Cellular Biology19941,126
41Sequences that regulate the divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae.Molecular and Cellular Biology19841,112
42Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and FeedbacksMolecular and Cellular Biology20121,110
43Regulation of Hypoxia-Inducible Factor 1α Expression and Function by the Mammalian Target of RapamycinMolecular and Cellular Biology20021,106
44Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life.Molecular and Cellular Biology19881,105
45Human Cyclin E, a Nuclear Protein Essential for the G1-to-S Phase TransitionMolecular and Cellular Biology19951,102
46Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine AcetylationMolecular and Cellular Biology20071,097
47Keap1 Is a Redox-Regulated Substrate Adaptor Protein for a Cul3-Dependent Ubiquitin Ligase ComplexMolecular and Cellular Biology20041,083
48Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell SurvivalMolecular and Cellular Biology20031,074
49Nuclear localization and regulation of erk- and rsk-encoded protein kinases.Molecular and Cellular Biology19921,071
50Bid Induces the Oligomerization and Insertion of Bax into the Outer Mitochondrial MembraneMolecular and Cellular Biology20001,053