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Top Articles

#TitleJournalYearCitations
1Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.Journal of Experimental Medicine19944,727
2Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte ActivationJournal of Experimental Medicine20004,394
3Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor Foxp3Journal of Experimental Medicine20034,213
4PLAQUE FORMATION AND ISOLATION OF PURE LINES WITH POLIOMYELITIS VIRUSESJournal of Experimental Medicine19544,028
5Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.Journal of Experimental Medicine19913,556
6IL-23 drives a pathogenic T cell population that induces autoimmune inflammationJournal of Experimental Medicine20053,550
7Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor.Journal of Experimental Medicine19923,473
8A STUDY OF FIXATION FOR ELECTRON MICROSCOPYJournal of Experimental Medicine19523,191
9STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPESJournal of Experimental Medicine19442,969
10B lymphocytes secrete antigen-presenting vesicles.Journal of Experimental Medicine19962,892
11Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo.Journal of Experimental Medicine19962,739
12Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl.Journal of Experimental Medicine19952,694
13THE CHEMOTACTIC EFFECT OF MIXTURES OF ANTIBODY AND ANTIGEN ON POLYMORPHONUCLEAR LEUCOCYTESJournal of Experimental Medicine19622,644
14Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones.Journal of Experimental Medicine19892,641
15A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-β– and retinoic acid–dependent mechanismJournal of Experimental Medicine20072,457
16SURFACE MARKERS ON HUMAN T AND B LYMPHOCYTESJournal of Experimental Medicine19722,411
17CD4+CD25+ Immunoregulatory T Cells Suppress Polyclonal T Cell Activation In Vitro by Inhibiting Interleukin 2 ProductionJournal of Experimental Medicine19982,323
18CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cellsJournal of Experimental Medicine20062,292
19DEMONSTRATION OF TUMOR-SPECIFIC ANTIGENS IN HUMAN COLONIC CARCINOMATA BY IMMUNOLOGICAL TOLERANCE AND ABSORPTION TECHNIQUESJournal of Experimental Medicine19652,282
20An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection.Journal of Experimental Medicine19932,280
21Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products.Journal of Experimental Medicine19952,275
22Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes.Journal of Experimental Medicine19822,155
23IMMUNIZATION OF DISSOCIATED SPLEEN CELL CULTURES FROM NORMAL MICEJournal of Experimental Medicine19672,122
24IDENTIFICATION OF A NOVEL CELL TYPE IN PERIPHERAL LYMPHOID ORGANS OF MICEJournal of Experimental Medicine19732,105
25STUDIES ON EXPERIMENTAL HYPERTENSIONJournal of Experimental Medicine19342,055
26Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptidesJournal of Experimental Medicine20062,043
27Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppressionJournal of Experimental Medicine20072,000
28IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channelJournal of Experimental Medicine20051,998
29Immunologic Self-Tolerance Maintained by Cd25+Cd4+Regulatory T Cells Constitutively Expressing Cytotoxic T Lymphocyte–Associated Antigen 4Journal of Experimental Medicine20001,977
30Cytotoxic T Lymphocyte–Associated Antigen 4 Plays an Essential Role in the Function of Cd25+Cd4+ Regulatory Cells That Control Intestinal InflammationJournal of Experimental Medicine20001,971
31LOCALIZATION OF ANTIGEN IN TISSUE CELLSJournal of Experimental Medicine19501,961
32Differential Expression of Chemokine Receptors and Chemotactic Responsiveness of Type 1 T Helper Cells (Th1s) and Th2sJournal of Experimental Medicine19981,948
33The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functionsJournal of Experimental Medicine20071,926
34CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation.Journal of Experimental Medicine19951,922
35MD-2, a Molecule that Confers Lipopolysaccharide Responsiveness on Toll-like Receptor 4Journal of Experimental Medicine19991,902
36Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity.Journal of Experimental Medicine19831,901
37Disseminated tuberculosis in interferon gamma gene-disrupted mice.Journal of Experimental Medicine19931,896
38Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes.Journal of Experimental Medicine19891,870
39Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation.Journal of Experimental Medicine19961,855
40Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression.Journal of Experimental Medicine19911,845
41SPECIFIC CARCINOEMBRYONIC ANTIGENS OF THE HUMAN DIGESTIVE SYSTEMJournal of Experimental Medicine19651,819
42Subsets of Human Dendritic Cell Precursors Express Different Toll-like Receptors and Respond to Different Microbial AntigensJournal of Experimental Medicine20011,777
43Proliferating dendritic cell progenitors in human blood.Journal of Experimental Medicine19941,774
44Intracellular Adenosine Triphosphate (ATP) Concentration: A Switch in the Decision Between Apoptosis and NecrosisJournal of Experimental Medicine19971,773
45Interferon and Granulopoiesis Signatures in Systemic Lupus Erythematosus BloodJournal of Experimental Medicine20031,760
46Viral Immune Evasion Due to Persistence of Activated T Cells Without Effector FunctionJournal of Experimental Medicine19981,733
47LEUKOCYTE LOCOMOTION AND CHEMOTAXISJournal of Experimental Medicine19731,718
48PD-L1 regulates the development, maintenance, and function of induced regulatory T cellsJournal of Experimental Medicine20091,711
49Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells.Journal of Experimental Medicine19891,700
50Phenotypic and functional features of human Th17 cellsJournal of Experimental Medicine20071,689