| # | Title | Journal | Year | Citations |
|---|
| 1 | Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge | Clinical Chemistry | 1972 | 26,892 |
| 2 | The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments | Clinical Chemistry | 2009 | 12,487 |
| 3 | Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge | Clinical Chemistry | 1972 | 9,549 |
| 4 | Enzymatic Determination of Total Serum Cholesterol | Clinical Chemistry | 1974 | 7,692 |
| 5 | Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine | Clinical Chemistry | 1993 | 5,582 |
| 6 | A simple method for clinical assay of superoxide dismutase. | Clinical Chemistry | 1988 | 3,238 |
| 7 | Modified Reagents for Determination of Urea and Ammonia | Clinical Chemistry | 1962 | 3,226 |
| 8 | Quantitative Determination of Serum Triglycerides by the Use of Enzymes | Clinical Chemistry | 1973 | 2,793 |
| 9 | The MicroRNA Spectrum in 12 Body Fluids | Clinical Chemistry | 2010 | 2,332 |
| 10 | Enzymatic determination of total serum cholesterol | Clinical Chemistry | 1974 | 2,224 |
| 11 | Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide. | Clinical Chemistry | 1982 | 2,053 |
| 12 | Dextran sulfate-Mg2+ precipitation procedure for quantitation of high-density-lipoprotein cholesterol. | Clinical Chemistry | 1982 | 2,037 |
| 13 | Aptamers: An Emerging Class of Molecules That Rival Antibodies in Diagnostics | Clinical Chemistry | 1999 | 1,882 |
| 14 | Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine | Clinical Chemistry | 1993 | 1,831 |
| 15 | Expressing the Modification of Diet in Renal Disease Study Equation for Estimating Glomerular Filtration Rate with Standardized Serum Creatinine Values | Clinical Chemistry | 2007 | 1,587 |
| 16 | Cholesterol determination in high-density lipoproteins separated by three different methods. | Clinical Chemistry | 1977 | 1,483 |
| 17 | Lipid peroxidation and antioxidants as biomarkers of tissue damage | Clinical Chemistry | 1995 | 1,455 |
| 18 | Ion Suppression in Mass Spectrometry | Clinical Chemistry | 2003 | 1,396 |
| 19 | Biomarkers of Oxidative Damage in Human Disease | Clinical Chemistry | 2006 | 1,395 |
| 20 | Serum Creatinine as an Index of Renal Function: New Insights into Old Concepts | Clinical Chemistry | 1992 | 1,333 |
| 21 | Preparation and Properties of a Cholesterol Oxidase from Nocardia sp. and Its Application to the Enzymatic Assay of Total Cholesterol in Serum | Clinical Chemistry | 1973 | 1,230 |
| 22 | Enzyme Immunoassay (EIA)/Enzyme-Linked Immunosorbent Assay (ELISA) | Clinical Chemistry | 2005 | 1,148 |
| 23 | High-Resolution Genotyping by Amplicon Melting Analysis Using LCGreen | Clinical Chemistry | 2003 | 1,122 |
| 24 | A Kinetic Photometric Method for Serum γ-Glutamyl Transpeptidase | Clinical Chemistry | 1969 | 1,110 |
| 25 | Molecular Diagnosis of a Novel Coronavirus (2019-nCoV) Causing an Outbreak of Pneumonia | Clinical Chemistry | 2020 | 1,098 |
| 26 | Recommendations for Improving Serum Creatinine Measurement: A Report from the Laboratory Working Group of the National Kidney Disease Education Program | Clinical Chemistry | 2006 | 1,057 |
| 27 | A simple method for clinical assay of superoxide dismutase | Clinical Chemistry | 1988 | 1,050 |
| 28 | Statistical Quality Control and Routine Data Processing for Radioimmunoassays and Immunoradiometric Assays | Clinical Chemistry | 1974 | 1,044 |
| 29 | Automated and Manual Direct Methods for the Determination of Blood Urea | Clinical Chemistry | 1965 | 1,033 |
| 30 | A peroxidase-coupled method for the colorimetric determination of serum triglycerides. | Clinical Chemistry | 1983 | 1,010 |
| 31 | Circulating Tumor Cells: Liquid Biopsy of Cancer | Clinical Chemistry | 2013 | 942 |
| 32 | The STARD Statement for Reporting Studies of Diagnostic Accuracy: Explanation and Elaboration | Clinical Chemistry | 2003 | 939 |
| 33 | Analytical Validation of a High-Sensitivity Cardiac Troponin T Assay | Clinical Chemistry | 2010 | 926 |
| 34 | Facts and Recommendations about Total Homocysteine Determinations: An Expert Opinion | Clinical Chemistry | 2004 | 913 |
| 35 | Nitrite and nitrate determinations in plasma: a critical evaluation | Clinical Chemistry | 1995 | 907 |
| 36 | Assay for the Measurement of Copeptin, a Stable Peptide Derived from the Precursor of Vasopressin | Clinical Chemistry | 2006 | 899 |
| 37 | Reagent for the enzymatic determination of serum total cholesterol with improved lipolytic efficiency. | Clinical Chemistry | 1983 | 887 |
| 38 | Total homocysteine in plasma or serum: methods and clinical applications | Clinical Chemistry | 1993 | 873 |
| 39 | Prostate-specific antigen in serum occurs predominantly in complex with alpha 1-antichymotrypsin | Clinical Chemistry | 1991 | 868 |
| 40 | Endocrine Regulation of Energy Metabolism: Review of Pathobiochemical and Clinical Chemical Aspects of Leptin, Ghrelin, Adiponectin, and Resistin | Clinical Chemistry | 2004 | 851 |
| 41 | Biological and clinical significance of haptoglobin polymorphism in humans | Clinical Chemistry | 1996 | 844 |
| 42 | Highly sensitive two-site immunoradiometric assay of parathyrin, and its clinical utility in evaluating patients with hypercalcemia. | Clinical Chemistry | 1987 | 822 |
| 43 | Role of serotonin in the pathophysiology of depression: focus on the serotonin transporter | Clinical Chemistry | 1994 | 812 |
| 44 | Modified reagents for determination of urea and ammonia | Clinical Chemistry | 1962 | 809 |
| 45 | Towards Complete and Accurate Reporting of Studies of Diagnostic Accuracy: The STARD Initiative | Clinical Chemistry | 2003 | 805 |
| 46 | Lipoperoxides in plasma as measured by liquid-chromatographic separation of malondialdehyde-thiobarbituric acid adduct. | Clinical Chemistry | 1987 | 795 |
| 47 | A New and Rapid Method for the Determination of Glucose by Measurement of Rate of Oxygen Consumption | Clinical Chemistry | 1968 | 794 |
| 48 | Plasma malondialdehyde as biomarker for oxidative stress: reference interval and effects of life-style factors | Clinical Chemistry | 1997 | 786 |
| 49 | Proteomics and Bioinformatics Approaches for Identification of Serum Biomarkers to Detect Breast Cancer | Clinical Chemistry | 2002 | 780 |
| 50 | Inflammation in Atherosclerosis: From Vascular Biology to Biomarker Discovery and Risk Prediction | Clinical Chemistry | 2008 | 779 |
