| # | Title | Journal | Year | Citations |
|---|
| 1 | Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease | Biochemistry | 1979 | 23,186 |
| 2 | Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane | Biochemistry | 1971 | 8,886 |
| 3 | Thermodynamics of protein association reactions: forces contributing to stability | Biochemistry | 1981 | 4,739 |
| 4 | Computed circular dichroism spectra for the evaluation of protein conformation | Biochemistry | 1969 | 3,738 |
| 5 | RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination | Biochemistry | 1977 | 3,705 |
| 6 | Spectroscopic Determination of Tryptophan and Tyrosine in Proteins* | Biochemistry | 1967 | 3,695 |
| 7 | Dominant forces in protein folding | Biochemistry | 1990 | 3,587 |
| 8 | Equilibrium Ultracentrifugation of Dilute Solutions* | Biochemistry | 1964 | 3,495 |
| 9 | Prediction of protein conformation | Biochemistry | 1974 | 3,416 |
| 10 | Comparison of Experimental Binding Data and Theoretical Models in Proteins Containing Subunits* | Biochemistry | 1966 | 2,990 |
| 11 | Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C | Biochemistry | 1984 | 2,807 |
| 12 | Hydrogen Ion Buffers for Biological Research* | Biochemistry | 1966 | 2,731 |
| 13 | Quenching of fluorescence by oxygen. Probe for structural fluctuations in macromolecules | Biochemistry | 1973 | 2,553 |
| 14 | Energy charge of the adenylate pool as a regulatory parameter. Interaction with feedback modifiers | Biochemistry | 1968 | 2,434 |
| 15 | Ribonucleic acid isolated by cesium chloride centrifugation | Biochemistry | 1974 | 2,345 |
| 16 | Conformational parameters for amino acids in helical, β-sheet, and random coil regions calculated from proteins | Biochemistry | 1974 | 2,245 |
| 17 | New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures | Biochemistry | 1980 | 2,200 |
| 18 | Determination of the helix and β form of proteins in aqueous solution by circular dichroism | Biochemistry | 1974 | 2,187 |
| 19 | Intracellular pH measurements in Ehrlich ascites tumor cells utilizing spectroscopic probes generated in situ | Biochemistry | 1979 | 2,154 |
| 20 | The chemical shift index: a fast and simple method for the assignment of protein secondary structure through NMR spectroscopy | Biochemistry | 1992 | 2,137 |
| 21 | Backbone Dynamics of a Free and a Phosphopeptide-Complexed Src Homology 2 Domain Studied by 15N NMR Relaxation | Biochemistry | 1994 | 2,136 |
| 22 | Estimation of globular protein secondary structure from circular dichroism | Biochemistry | 1981 | 2,115 |
| 23 | Determination of the secondary structures of proteins by circular dichroism and optical rotatory dispersion | Biochemistry | 1972 | 2,032 |
| 24 | Dithiothreitol, a New Protective Reagent for SH Groups* | Biochemistry | 1964 | 1,935 |
| 25 | The carboxy terminus of the .beta. amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease | Biochemistry | 1993 | 1,870 |
| 26 | Backbone dynamics of proteins as studied by nitrogen-15 inverse detected heteronuclear NMR spectroscopy: application to staphylococcal nuclease | Biochemistry | 1989 | 1,856 |
| 27 | Polycyclic aromatic hydrocarbons physically intercalate into duplex regions of denatured DNA | Biochemistry | 1987 | 1,842 |
| 28 | Solute perturbation of protein fluorescence. Quenching of the tryptophyl fluorescence of model compounds and of lysozyme by iodide ion | Biochemistry | 1971 | 1,788 |
| 29 | The coagulation cascade: initiation, maintenance, and regulation | Biochemistry | 1991 | 1,736 |
| 30 | Unfolding free energy changes determined by the linear extrapolation method. 1. Unfolding of phenylmethanesulfonyl .alpha.-chymotrypsin using different denaturants | Biochemistry | 1988 | 1,704 |
| 31 | Detection of two restriction endonuclease activities in Haemophilus parainfluenzae using analytical agarose-ethidium bromide electrophoresis | Biochemistry | 1973 | 1,700 |
| 32 | Zinc coordination, function, and structure of zinc enzymes and other proteins | Biochemistry | 1990 | 1,695 |
| 33 | Dynamics of ligand binding to myoglobin | Biochemistry | 1975 | 1,613 |
| 34 | Intrinsic Disorder and Protein Function† | Biochemistry | 2002 | 1,605 |
| 35 | Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate | Biochemistry | 1988 | 1,597 |
| 36 | Phosphatidylcholine vesicles. Formation and physical characteristics | Biochemistry | 1969 | 1,552 |
| 37 | Determination of protein secondary structure by Fourier transform infrared spectroscopy: A critical assessment | Biochemistry | 1993 | 1,500 |
| 38 | Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-.ANG. resolution | Biochemistry | 1981 | 1,476 |
| 39 | Rate of depurination of native deoxyribonucleic acid | Biochemistry | 1972 | 1,453 |
| 40 | NACP, A Protein Implicated in Alzheimer's Disease and Learning, Is Natively Unfolded | Biochemistry | 1996 | 1,446 |
| 41 | Molecular weight estimation and separation of ribonucleic acid by electrophoresis in agarose-acrylamide composite gels | Biochemistry | 1968 | 1,445 |
| 42 | Use of a mixture of proteinase-free collagenases for the specific assay of radioactive collagen in the presence of other proteins | Biochemistry | 1971 | 1,407 |
| 43 | Basement membrane complexes with biological activity | Biochemistry | 1986 | 1,399 |
| 44 | Use of resonance energy transfer to monitor membrane fusion | Biochemistry | 1981 | 1,312 |
| 45 | Mechanism of adenosine triphosphate hydrolysis by actomyosin | Biochemistry | 1971 | 1,296 |
| 46 | Lipid sorting in epithelial cells | Biochemistry | 1988 | 1,274 |
| 47 | Neither .DELTA.- nor .LAMBDA.-tris(phenanthroline)ruthenium(II) binds to DNA by classical intercalation | Biochemistry | 1992 | 1,268 |
| 48 | Protein secondary structures in water from second-derivative amide I infrared spectra | Biochemistry | 1990 | 1,251 |
| 49 | Metabolic profiles of three fiber types of skeletal muscle in guinea pigs and rabbits | Biochemistry | 1972 | 1,240 |
| 50 | Procedure for the rapid, large-scale purification of Escherichia coli DNA-dependent RNA polymerase involving polymin P precipitation and DNA-cellulose chromatography | Biochemistry | 1975 | 1,232 |
