| # | Title | Journal | Year | Citations |
|---|
| 1 | A convenient synthesis of acetylenes: catalytic substitutions of acetylenic hydrogen with bromoalkenes, iodoarenes and bromopyridines | Tetrahedron Letters | 1975 | 4,764 |
| 2 | Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis | Tetrahedron Letters | 1981 | 1,964 |
| 3 | A new stereospecific cross-coupling by the palladium-catalyzed reaction of 1-alkenylboranes with 1-alkenyl or 1-alkynyl halides | Tetrahedron Letters | 1979 | 1,848 |
| 4 | N-methoxy-n-methylamides as effective acylating agents | Tetrahedron Letters | 1981 | 1,697 |
| 5 | Pyridinium chlorochromate. An efficient reagent for oxidation of primary and secondary alcohols to carbonyl compounds | Tetrahedron Letters | 1975 | 1,625 |
| 6 | The use of microwave ovens for rapid organic synthesis | Tetrahedron Letters | 1986 | 1,525 |
| 7 | A synthetic method for formyl→ethynyl conversion (RCHO→RCCH or RCCR′) | Tetrahedron Letters | 1972 | 1,488 |
| 8 | Definition of aromaticity basing on the harmonic oscillator model | Tetrahedron Letters | 1972 | 1,126 |
| 9 | New N- and O-arylations with phenylboronic acids and cupric acetate | Tetrahedron Letters | 1998 | 1,067 |
| 10 | Application of commercial microwave ovens to organic synthesis. | Tetrahedron Letters | 1986 | 1,054 |
| 11 | Direct synthesis of Z-unsaturated esters. A useful modification of the horner-emmons olefination. | Tetrahedron Letters | 1983 | 1,024 |
| 12 | New coupling reagents in peptide chemistry | Tetrahedron Letters | 1989 | 963 |
| 13 | New aryl/heteroaryl CN bond cross-coupling reactions via arylboronic acid/cupric acetate arylation | Tetrahedron Letters | 1998 | 963 |
| 14 | An improved catalytic OsO4 oxidation of olefins to -1,2-glycols using tertiary amine oxides as the oxidant | Tetrahedron Letters | 1976 | 940 |
| 15 | Useful procedures for the oxidation of alcohols involving pyridinium dichromate in aprotic media | Tetrahedron Letters | 1979 | 935 |
| 16 | 2- and 4-Nitrobenzenesulfonamides: Exceptionally versatile means for preparation of secondary amines and protection of amines | Tetrahedron Letters | 1995 | 906 |
| 17 | Increased ring closing metathesis activity of ruthenium-based olefin metathesis catalysts coordinated with imidazolin-2-ylidene ligands | Tetrahedron Letters | 1999 | 882 |
| 18 | Solid-phase synthesis of protected peptide fragments using a trialkoxy-diphenyl-methylester resin. | Tetrahedron Letters | 1987 | 881 |
| 19 | Horner-wadsworth-emmons reaction: Use of lithium chloride and an amine for base-sensitive compounds | Tetrahedron Letters | 1984 | 871 |
| 20 | Torsional strain involving partial bonds. The stereochemistry of the lithium aluminium hydride reduction of some simple open-chain ketones | Tetrahedron Letters | 1968 | 855 |
| 21 | Iodonium ion promoted reactions at the anomeric centre. II An efficient thioglycoside mediated approach toward the formation of 1,2-trans linked glycosides and glycosidic esters | Tetrahedron Letters | 1990 | 840 |
| 22 | Palladium-catalyzed synthesis of arylamines from aryl halides. Mechanistic studies lead to coupling in the absence of tin reagents | Tetrahedron Letters | 1995 | 801 |
| 23 | Synthesis of diaryl ethers through the copper-promoted arylation of phenols with arylboronic acids. An expedient synthesis of thyroxine | Tetrahedron Letters | 1998 | 796 |
| 24 | Direct room temperature esterification of carboxylic acids | Tetrahedron Letters | 1978 | 687 |
| 25 | PyBOP®: A new peptide coupling reagent devoid of toxic by-product | Tetrahedron Letters | 1990 | 628 |
| 26 | Specific removal of o-methoxybenzyl protection by DDQ oxidation. | Tetrahedron Letters | 1982 | 627 |
| 27 | Catalytic asymmetric epoxidation of unfunctionalized olefins | Tetrahedron Letters | 1990 | 627 |
| 28 | Stability and structural features of the duplexes containing nucleoside analogues with a fixed N-type conformation, 2′-O,4′-C-methyleneribonucleosides | Tetrahedron Letters | 1998 | 627 |
| 29 | Iodonium promoted reactions of disarmed thioglycosides | Tetrahedron Letters | 1990 | 578 |
| 30 | Reaction of zirconocene dichloride with alkyllithiums or alkyl grignard reagents as a convenient method for generating a “zirconocene” equivalant and its use in zirconium-promoted cyclization of alkenes, alkynes, dienes, enynes, and diynes | Tetrahedron Letters | 1986 | 561 |
| 31 | A mild, general method for conversion of esters to amides | Tetrahedron Letters | 1977 | 556 |
| 32 | The preparation of N-carboxyanhydrides of α-amino acids using bis(trichloromethyl)carbonate | Tetrahedron Letters | 1988 | 554 |
| 33 | Phosphinoaryl- and phosphinoalkyloxazolines as new chiral ligands for enantioselective catalysis: Very high enantioselectivity in palladium catalyzed allylic substitutions | Tetrahedron Letters | 1993 | 554 |
| 34 | Syntheses a l'aide de sulfones v(+)- methode de synthese generale de doubles liaisons. | Tetrahedron Letters | 1973 | 550 |
| 35 | An investigation of several deoxynucleoside phosphoramidites useful for synthesizing deoxyoligonucleotides | Tetrahedron Letters | 1983 | 546 |
| 36 | Facile synthesis of p-tert-butylthiacalix[4]arene by the reaction of p-tert-butylphenol with elemental sulfur in the presence of a base | Tetrahedron Letters | 1997 | 544 |
| 37 | Synthesis of 2′-O,4′-C-methyleneuridine and -cytidine. Novel bicyclic nucleosides having a fixed C3, -endo sugar puckering | Tetrahedron Letters | 1997 | 543 |
| 38 | Aromatic substitution of styrene-palladium chloride complex | Tetrahedron Letters | 1967 | 536 |
| 39 | Comprehensive organic chemistry | Tetrahedron Letters | 1978 | 534 |
| 40 | Asymmetric catalytic cyclopropanation of olefins: bis-oxazoline copper complexes | Tetrahedron Letters | 1990 | 516 |
| 41 | Synthesis and metathesis reactions of a phosphine-free dihydroimidazole carbene ruthenium complex | Tetrahedron Letters | 2000 | 501 |
| 42 | Pyridine-derived triflating reagents: An improved preparation of vinyl triflates from metallo enolates. | Tetrahedron Letters | 1992 | 493 |
| 43 | Hűckel molecular orbitals of Mőbius-type conformations of annulenes | Tetrahedron Letters | 1964 | 482 |
| 44 | Stereochemistry of alternating polyol chains: 13C NMR analysis of 1,3-diol acetonides | Tetrahedron Letters | 1990 | 471 |
| 45 | Contrasteric carboximide hydrolysis with lithium hydroperoxide | Tetrahedron Letters | 1987 | 469 |
| 46 | A novel method for phosphorylation of nucleosides to 5′-nucleotides | Tetrahedron Letters | 1967 | 455 |
| 47 | Organic syntheses by means of noble metal compounds XVII. Reaction of π-allylpalladium chloride with nucleophiles | Tetrahedron Letters | 1965 | 451 |
| 48 | A new model for calculating atomic charges in molecules | Tetrahedron Letters | 1978 | 446 |
| 49 | A novel synthesis of functional dithioesters, dithiocarbamates, xanthates and trithiocarbonates | Tetrahedron Letters | 1999 | 441 |
| 50 | A facile procedure for acetalization under aprotic conditions | Tetrahedron Letters | 1980 | 440 |
