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Top Articles

#TitleJournalYearCitations
1Matrix metalloproteinases (MMPs), the main extracellular matrix (ECM) enzymes in collagen degradation, as a target for anticancer drugsJournal of Enzyme Inhibition and Medicinal Chemistry2016692
2A comprehensive review on tyrosinase inhibitorsJournal of Enzyme Inhibition and Medicinal Chemistry2019597
3Review ArticleJournal of Enzyme Inhibition and Medicinal Chemistry2004595
4How many carbonic anhydrase inhibition mechanisms exist?Journal of Enzyme Inhibition and Medicinal Chemistry2016588
5Structure-based drug discovery of carbonic anhydrase inhibitorsJournal of Enzyme Inhibition and Medicinal Chemistry2012554
6Skin whitening agents: medicinal chemistry perspective of tyrosinase inhibitorsJournal of Enzyme Inhibition and Medicinal Chemistry2017554
7The role of fluorine in medicinal chemistryJournal of Enzyme Inhibition and Medicinal Chemistry2007540
8Inhibition of SARS-CoV 3CL protease by flavonoidsJournal of Enzyme Inhibition and Medicinal Chemistry2020508
9Pharmacological significance of triazole scaffoldJournal of Enzyme Inhibition and Medicinal Chemistry2011423
10Beta-lactamase database (BLDB) – structure and functionJournal of Enzyme Inhibition and Medicinal Chemistry2017405
11An overview of the alpha-, beta- and gamma-carbonic anhydrases fromBacteria: can bacterial carbonic anhydrases shed new light on evolution of bacteria?Journal of Enzyme Inhibition and Medicinal Chemistry2015328
12Biological Evaluation of Several Coumarin Derivatives Designed as Possible Anti-inflammatory/Antioxidant AgentsJournal of Enzyme Inhibition and Medicinal Chemistry2003287
13Carbonic anhydrases: from biomedical applications of the inhibitors and activators to biotechnological use for CO2 captureJournal of Enzyme Inhibition and Medicinal Chemistry2013278
14α-Glucosidase inhibition by flavonoids: an in vitro and in silico structure–activity relationship studyJournal of Enzyme Inhibition and Medicinal Chemistry2017274
15Sulfa and trimethoprim-like drugs – antimetabolites acting as carbonic anhydrase, dihydropteroate synthase and dihydrofolate reductase inhibitorsJournal of Enzyme Inhibition and Medicinal Chemistry2014255
16Evaluation of polyphenols from Broussonetia papyrifera as coronavirus protease inhibitorsJournal of Enzyme Inhibition and Medicinal Chemistry2017233
17Natural, semisynthetic and synthetic tyrosinase inhibitorsJournal of Enzyme Inhibition and Medicinal Chemistry2016211
18Isatin-derived Antibacterial and Antifungal Compounds and their Transition Metal ComplexesJournal of Enzyme Inhibition and Medicinal Chemistry2004210
19Scutellaria baicalensis extract and baicalein inhibit replication of SARS-CoV-2 and its 3C-like protease in vitroJournal of Enzyme Inhibition and Medicinal Chemistry2021206
20Synthesis of 4-benzyl-1,3-thiazole derivatives as potential anti-inflammatory agents: An analogue-based drug design approachJournal of Enzyme Inhibition and Medicinal Chemistry2009196
21Antioxidant activity of taxifolin: an activity–structure relationshipJournal of Enzyme Inhibition and Medicinal Chemistry2016191
22Ciprofloxacin: review on developments in synthetic, analytical, and medicinal aspectsJournal of Enzyme Inhibition and Medicinal Chemistry2010190
23Structural annotation of human carbonic anhydrasesJournal of Enzyme Inhibition and Medicinal Chemistry2013189
24Chalcones isolated fromAngelica keiskeiinhibit cysteine proteases of SARS-CoVJournal of Enzyme Inhibition and Medicinal Chemistry2016189
25Medicinal significance of benzothiazole scaffold: an insight viewJournal of Enzyme Inhibition and Medicinal Chemistry2013188
26Phenolic phytochemical displaying SARS-CoV papain-like protease inhibition from the seeds of Psoralea corylifoliaJournal of Enzyme Inhibition and Medicinal Chemistry2014175
27Rosmarinic acid inhibits some metabolic enzymes including glutathioneS-transferase, lactoperoxidase, acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase isoenzymesJournal of Enzyme Inhibition and Medicinal Chemistry2016173
28Taking advantage of tumor cell adaptations to hypoxia for developing new tumor markers and treatment strategiesJournal of Enzyme Inhibition and Medicinal Chemistry2009167
29In vitroantioxidant activity of silymarinJournal of Enzyme Inhibition and Medicinal Chemistry2009166
30Zinc binding groups for histone deacetylase inhibitorsJournal of Enzyme Inhibition and Medicinal Chemistry2018162
31A series of cinnamic acid derivatives and their inhibitory activity on intestinal α-glucosidaseJournal of Enzyme Inhibition and Medicinal Chemistry2009159
32Oleanolic acid and related derivatives as medicinally important compoundsJournal of Enzyme Inhibition and Medicinal Chemistry2008154
33Metalloantibiotics: Synthesis and Antibacterial Activity of Cobalt(II), Copper(II), Nickel(II) and Zinc(II) Complexes of KefzolJournal of Enzyme Inhibition and Medicinal Chemistry2004153
34Functional constituents of wild and cultivated Goji (L. barbarum L.) leaves: phytochemical characterization, biological profile, and computational studiesJournal of Enzyme Inhibition and Medicinal Chemistry2017151
35A new approach to antiglaucoma drugs: carbonic anhydrase inhibitors with or without NO donating moieties. Mechanism of action and preliminary pharmacologyJournal of Enzyme Inhibition and Medicinal Chemistry2012150
36Metal binding and antibacterial activity of ciprofloxacin complexesJournal of Enzyme Inhibition and Medicinal Chemistry2005147
37Zinc Complexes of Benzothiazole-derived Schiff Bases with Antibacterial ActivityJournal of Enzyme Inhibition and Medicinal Chemistry2003146
38The effect of caffeic acid phenethyl ester (CAPE) on metabolic enzymes including acetylcholinesterase, butyrylcholinesterase, glutathione S-transferase, lactoperoxidase, and carbonic anhydrase isoenzymes I, II, IX, and XIIJournal of Enzyme Inhibition and Medicinal Chemistry2016142
39Benzothiazole derivatives as anticancer agentsJournal of Enzyme Inhibition and Medicinal Chemistry2020140
40Heavy Metal Ions Inhibition of Jack Bean Urease: Potential for Rapid Contaminant ProbingJournal of Enzyme Inhibition and Medicinal Chemistry2004138
41Tyrosinase Inhibition: General and Applied AspectsJournal of Enzyme Inhibition and Medicinal Chemistry2002137
42In-vitro antibacterial, antifungal and cytotoxic properties of sulfonamide—derived Schiff's bases and their metal complexesJournal of Enzyme Inhibition and Medicinal Chemistry2005133
43Antioxidant, antiradical, and anticholinergic properties of cynarin purified from the Illyrian thistle (Onopordum illyricum L.)Journal of Enzyme Inhibition and Medicinal Chemistry2016133
44Biomimetic CO2 capture using a highly thermostable bacterial α-carbonic anhydrase immobilized on a polyurethane foamJournal of Enzyme Inhibition and Medicinal Chemistry2014131
45Mini ReviewJournal of Enzyme Inhibition and Medicinal Chemistry2004128
46A magnificent enzyme superfamily: carbonic anhydrases, their purification and characterizationJournal of Enzyme Inhibition and Medicinal Chemistry2016128
47In-vitro antibacterial, antifungal and cytotoxic activities of some coumarins and their metal complexesJournal of Enzyme Inhibition and Medicinal Chemistry2005126
48Dithiocarbamates strongly inhibit the β-class carbonic anhydrases fromMycobacterium tuberculosisJournal of Enzyme Inhibition and Medicinal Chemistry2013125
49Synthesis of 4,5-disubstituted-2-thioxo-1,2,3,4-tetrahydropyrimidines and investigation of their acetylcholinesterase, butyrylcholinesterase, carbonic anhydrase I/II inhibitory and antioxidant activitiesJournal of Enzyme Inhibition and Medicinal Chemistry2016125
50Synthesis of diaryl ethers with acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase inhibitory actionsJournal of Enzyme Inhibition and Medicinal Chemistry2016125