| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 2 | Iron, brain ageing and neurodegenerative disorders | Nature Reviews Neuroscience | 2004 | 1,581 |
| 3 | Consensus on women’s health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group | Fertility and Sterility | 2012 | 1,494 |
| 4 | Exercise Guidelines for Cancer Survivors: Consensus Statement from International Multidisciplinary Roundtable | Medicine and Science in Sports and Exercise | 2019 | 1,443 |
| 5 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 6 | Consensus Statement on Management of Intersex Disorders | Pediatrics | 2006 | 1,378 |
| 7 | Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome†‡ | Human Reproduction | 2018 | 1,015 |
| 8 | Twenty-five years of quantitative PCR for gene expression analysis | BioTechniques | 2008 | 961 |
| 9 | Part 1: Executive Summary | Circulation | 2010 | 902 |
| 10 | Global Disorders of Sex Development Update since 2006: Perceptions, Approach and Care | Hormone Research in Paediatrics | 2016 | 852 |
| 11 | Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 | Cell Death and Differentiation | 2015 | 811 |
| 12 | Global Epidemiology of Pediatric Severe Sepsis: The Sepsis Prevalence, Outcomes, and Therapies Study | American Journal of Respiratory and Critical Care Medicine | 2015 | 762 |
| 13 | Anemia, Blood Loss, and Blood Transfusions in North American Children in the Intensive Care Unit | American Journal of Respiratory and Critical Care Medicine | 2008 | 760 |
| 14 | COVID‐19 and Older Adults: What We Know | Journal of the American Geriatrics Society | 2020 | 729 |
| 15 | Diabetic Retinopathy | Diabetes | 2006 | 673 |
| 16 | A systematic review of the diagnosis and treatment of primary hyperparathyroidism from 1995 to 2003 | Otolaryngology - Head and Neck Surgery | 2005 | 639 |
| 17 | Examination of US Puberty-Timing Data from 1940 to 1994 for Secular Trends: Panel Findings | Pediatrics | 2008 | 551 |
| 18 | Diabetes Attitudes, Wishes and Needs second study (DAWN2™): Cross‐national benchmarking of diabetes‐related psychosocial outcomes for people with diabetes | Diabetic Medicine | 2013 | 540 |
| 19 | A new view of diabetic retinopathy: a neurodegenerative disease of the eye | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2003 | 535 |
| 20 | Identification of a membrane-binding domain within the amino-terminal region of human immunodeficiency virus type 1 Gag protein which interacts with acidic phospholipids | Journal of Virology | 1994 | 535 |
| 21 | Optical brain monitoring for operator training and mental workload assessment | NeuroImage | 2012 | 526 |
| 22 | Neuropathological examination suggests impaired brain iron acquisition in restless legs syndrome | Neurology | 2003 | 522 |
| 23 | Genome-wide Analyses Identify KIF5A as a Novel ALS Gene | Neuron | 2018 | 517 |
| 24 | A population-based study of cardiovascular disease mortality risk in US cancer patients | European Heart Journal | 2019 | 501 |
| 25 | Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program | Nature Genetics | 2018 | 497 |
| 26 | Discovery and evaluation of inhibitors of human sphingosine kinase | Cancer Research | 2003 | 493 |
| 27 | Bloom’s taxonomy of cognitive learning objectives | Journal of the Medical Library Association: JMLA | 2015 | 470 |
| 28 | Exome-wide association study of plasma lipids in >300,000 individuals | Nature Genetics | 2017 | 470 |
| 29 | Sleep apnea is a manifestation of the metabolic syndrome | Sleep Medicine Reviews | 2005 | 468 |
| 30 | Regulation of tight junctions and loss of barrier function in pathophysiology | International Journal of Biochemistry and Cell Biology | 2004 | 467 |
| 31 | Oral Appliances for the Treatment of Snoring and Obstructive Sleep Apnea: A Review | Sleep | 1995 | 458 |
| 32 | American College of Sports Medicine Roundtable Report on Physical Activity, Sedentary Behavior, and Cancer Prevention and Control | Medicine and Science in Sports and Exercise | 2019 | 455 |
| 33 | The Ins2AkitaMouse as a Model of Early Retinal Complications in Diabetes | Medicine and Science in Sports and Exercise | 2005 | 442 |
| 34 | The management of anovulatory infertility in women with polycystic ovary syndrome: an analysis of the evidence to support the development of global WHO guidance | Human Reproduction Update | 2016 | 440 |
| 35 | Exercise is medicine in oncology: Engaging clinicians to help patients move through cancer | Ca-A Cancer Journal for Clinicians | 2019 | 412 |
| 36 | A microfluidic device for continuous, real time blood plasma separation | Lab on A Chip | 2006 | 399 |
| 37 | Central Nervous System Control of Gastrointestinal Motility and Secretion and Modulation of Gastrointestinal Functions | Lab on A Chip | 2014 | 381 |
| 38 | TNF-α mediates chemokine and cytokine expression and renal injury in cisplatin nephrotoxicity | Journal of Clinical Investigation | 2002 | 370 |
| 39 | RVTESTS: an efficient and comprehensive tool for rare variant association analysis using sequence data | Bioinformatics | 2016 | 366 |
| 40 | Association of cardiovascular disease and 10 other pre-existing comorbidities with COVID-19 mortality: A systematic review and meta-analysis | PLoS ONE | 2020 | 365 |
| 41 | Effect of Exogenous Surfactant (Calfactant) in Pediatric Acute Lung InjuryA Randomized Controlled Trial | JAMA - Journal of the American Medical Association | 2005 | 364 |
| 42 | Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes | Nature Genetics | 2018 | 356 |
| 43 | Urinary TIMP-2 and IGFBP7 as Early Biomarkers of Acute Kidney Injury and Renal Recovery following Cardiac Surgery | PLoS ONE | 2014 | 345 |
| 44 | Retinal ganglion cells in diabetes | Journal of Physiology | 2008 | 341 |
| 45 | Clinical Presentation, Treatment, and Complications of Malignant Hyperthermia in North America from 1987 to 2006 | Anesthesia and Analgesia | 2010 | 327 |
| 46 | Biochemical Verification of Tobacco Use and Abstinence: 2019 Update | Nicotine and Tobacco Research | 2020 | 325 |
| 47 | Frozen versus fresh single blastocyst transfer in ovulatory women: a multicentre, randomised controlled trial | Lancet, The | 2019 | 323 |
| 48 | Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations | Nature Communications | 2015 | 314 |
| 49 | Learning, Attention, Writing, and Processing Speed in Typical Children and Children with ADHD, Autism, Anxiety, Depression, and Oppositional-Defiant Disorder | Child Neuropsychology | 2007 | 310 |
| 50 | Cardiac resynchronization therapy and the relationship of percent biventricular pacing to symptoms and survival | Heart Rhythm | 2011 | 302 |
