| # | Title | Journal | Year | Citations |
|---|
| 1 | 2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults | JAMA - Journal of the American Medical Association | 2014 | 6,625 |
| 2 | Mild cognitive impairment as a diagnostic entity | Journal of Internal Medicine | 2004 | 6,255 |
| 3 | Diagnostic criteria for multiple sclerosis: 2005 revisions to the “McDonald Criteria” | Annals of Neurology | 2005 | 4,495 |
| 4 | Trends in Prevalence and Outcome of Heart Failure with Preserved Ejection Fraction | New England Journal of Medicine | 2006 | 3,601 |
| 5 | Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America Guidelines for Developing an Institutional Program to Enhance Antimicrobial Stewardship | Clinical Infectious Diseases | 2007 | 3,390 |
| 6 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 7 | A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis | Lancet, The | 2004 | 2,839 |
| 8 | Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders | Nature | 2011 | 2,806 |
| 9 | Toward an Integrated Clinical, Molecular and Serological Classification of Inflammatory Bowel Disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology | Canadian Journal of Gastroenterology & Hepatology | 2005 | 2,711 |
| 10 | Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease | Nature Genetics | 2009 | 2,697 |
| 11 | The Natural History of Nonalcoholic Fatty Liver Disease: A Population-Based Cohort Study | Gastroenterology | 2005 | 2,544 |
| 12 | Clinical diagnostic criteria for dementia associated with Parkinson's disease | Movement Disorders | 2007 | 2,497 |
| 13 | A global view of hepatocellular carcinoma: trends, risk, prevention and management | Nature Reviews Gastroenterology and Hepatology | 2019 | 2,482 |
| 14 | The NAFLD fibrosis score: A noninvasive system that identifies liver fibrosis in patients with NAFLD | Hepatology | 2007 | 2,448 |
| 15 | Revised diagnostic criteria for neuromyelitis optica | Neurology | 2006 | 2,438 |
| 16 | Mild cognitive impairment | Lancet, The | 2006 | 2,401 |
| 17 | Weight and Type 2 Diabetes after Bariatric Surgery: Systematic Review and Meta-analysis | American Journal of Medicine | 2009 | 2,253 |
| 18 | Phase 3 Trial of 177Lu-Dotatate for Midgut Neuroendocrine Tumors | New England Journal of Medicine | 2017 | 2,206 |
| 19 | B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion | Nature Medicine | 1999 | 2,200 |
| 20 | Anti-TNF Antibody Therapy in Rheumatoid Arthritis and the Risk of Serious Infections and Malignancies | JAMA - Journal of the American Medical Association | 2006 | 2,190 |
| 21 | Genome-wide association study identifies novel breast cancer susceptibility loci | Nature | 2007 | 2,165 |
| 22 | Effect of Oral Milrinone on Mortality in Severe Chronic Heart Failure | New England Journal of Medicine | 1991 | 2,137 |
| 23 | Burden of liver diseases in the world | Journal of Hepatology | 2019 | 2,125 |
| 24 | Oncogenic Signaling Pathways in The Cancer Genome Atlas | Cell | 2018 | 2,111 |
| 25 | Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017 | JAMA Surgery | 2017 | 2,099 |
| 26 | Cardiovascular Magnetic Resonance in Myocarditis: A JACC White Paper | Journal of the American College of Cardiology | 2009 | 2,055 |
| 27 | Naturally occurring p16Ink4a-positive cells shorten healthy lifespan | Nature | 2016 | 2,016 |
| 28 | IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel | Journal of Experimental Medicine | 2005 | 1,998 |
| 29 | The role of senescent cells in ageing | Nature | 2014 | 1,915 |
| 30 | The spectrum of neuromyelitis optica | Lancet Neurology, The | 2007 | 1,897 |
| 31 | Percutaneous closure of the left atrial appendage versus warfarin therapy for prevention of stroke in patients with atrial fibrillation: a randomised non-inferiority trial | Lancet, The | 2009 | 1,876 |
| 32 | Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17 | Nature | 2006 | 1,816 |
| 33 | Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects | Annals of Neurology | 2009 | 1,803 |
| 34 | Vitamin E and Donepezil for the Treatment of Mild Cognitive Impairment | New England Journal of Medicine | 2005 | 1,709 |
| 35 | Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease | Nature Genetics | 2011 | 1,708 |
| 36 | Metabolic Syndrome and Risk of Incident Cardiovascular Events and Death | Journal of the American College of Cardiology | 2007 | 1,614 |
| 37 | Inflammatory bowel disease: clinical aspects and established and evolving therapies | Lancet, The | 2007 | 1,593 |
| 38 | Diagnosis and Management of Prosthetic Joint Infection: Clinical Practice Guidelines by the Infectious Diseases Society of Americaa | Clinical Infectious Diseases | 2013 | 1,593 |
| 39 | CPAT: Coding-Potential Assessment Tool using an alignment-free logistic regression model | Nucleic Acids Research | 2013 | 1,574 |
| 40 | Cellular senescence in aging and age-related disease: from mechanisms to therapy | Nature Medicine | 2015 | 1,547 |
| 41 | Alzheimer's Disease Neuroimaging Initiative (ADNI) | Neurology | 2010 | 1,530 |
| 42 | Guidelines for Management of Small Pulmonary Nodules Detected on CT Scans: A Statement from the Fleischner Society | Radiology | 2005 | 1,482 |
| 43 | ACR Thyroid Imaging, Reporting and Data System (TI-RADS): White Paper of the ACR TI-RADS Committee | Journal of the American College of Radiology | 2017 | 1,473 |
| 44 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 45 | Mayo clinical Text Analysis and Knowledge Extraction System (cTAKES): architecture, component evaluation and applications | Journal of the American Medical Informatics Association: JAMIA | 2010 | 1,413 |
| 46 | Technology-Enhanced Simulation for Health Professions Education | JAMA - Journal of the American Medical Association | 2011 | 1,379 |
| 47 | The model for end-stage liver disease (MELD) | Hepatology | 2007 | 1,365 |
| 48 | Association of bodyweight with total mortality and with cardiovascular events in coronary artery disease: a systematic review of cohort studies | Lancet, The | 2006 | 1,342 |
| 49 | First performance evaluation of a dual-source CT (DSCT) system | European Radiology | 2006 | 1,296 |
| 50 | Pathways of clathrin-independent endocytosis | Nature Reviews Molecular Cell Biology | 2007 | 1,294 |
