| # | Title | Journal | Year | Citations |
|---|
| 1 | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 | Cell Death and Differentiation | 2018 | 4,036 |
| 2 | The IntCal20 Northern Hemisphere Radiocarbon Age Calibration Curve (0–55 cal kBP) | Radiocarbon | 2020 | 3,502 |
| 3 | Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): a randomised controlled trial | Lancet, The | 2010 | 2,002 |
| 4 | Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene | Journal of Clinical Investigation | 2003 | 1,957 |
| 5 | Future Coastal Population Growth and Exposure to Sea-Level Rise and Coastal Flooding - A Global Assessment | PLoS ONE | 2015 | 1,613 |
| 6 | Policy: Map the interactions between Sustainable Development Goals | Nature | 2016 | 1,321 |
| 7 | Efficacy and Safety of Vismodegib in Advanced Basal-Cell Carcinoma | New England Journal of Medicine | 2012 | 1,201 |
| 8 | SWAT2000: current capabilities and research opportunities in applied watershed modelling | Hydrological Processes | 2005 | 1,089 |
| 9 | Analysis of shared heritability in common disorders of the brain | Science | 2018 | 1,085 |
| 10 | Why protect nature? Rethinking values and the environment | Proceedings of the National Academy of Sciences of the United States of America | 2016 | 1,074 |
| 11 | Pancreatic Intraepithelial Neoplasia | American Journal of Surgical Pathology | 2001 | 1,051 |
| 12 | TRY plant trait database – enhanced coverage and open access | Global Change Biology | 2020 | 1,038 |
| 13 | Maintenance Therapy with Certolizumab Pegol for Crohn's Disease | New England Journal of Medicine | 2007 | 1,033 |
| 14 | Valuing nature’s contributions to people: the IPBES approach | Current Opinion in Environmental Sustainability | 2017 | 1,007 |
| 15 | PD-1 Blockade with Cemiplimab in Advanced Cutaneous Squamous-Cell Carcinoma | New England Journal of Medicine | 2018 | 997 |
| 16 | Ustekinumab Induction and Maintenance Therapy in Refractory Crohn's Disease | New England Journal of Medicine | 2012 | 984 |
| 17 | An Illustrated Consensus on the Classification of Pancreatic Intraepithelial Neoplasia and Intraductal Papillary Mucinous Neoplasms | American Journal of Surgical Pathology | 2004 | 964 |
| 18 | Vegetation of Europe: hierarchical floristic classification system of vascular plant, bryophyte, lichen, and algal communities | Applied Vegetation Science | 2016 | 905 |
| 19 | Efficacy and Safety of Dupilumab in Glucocorticoid-Dependent Severe Asthma | New England Journal of Medicine | 2018 | 816 |
| 20 | Resin-ceramic bonding: A review of the literature | Journal of Prosthetic Dentistry | 2003 | 786 |
| 21 | Admission criteria for immunogerontological studies in man: The senieur protocol | Mechanisms of Ageing and Development | 1984 | 747 |
| 22 | NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal -defensin expression | Gut | 2004 | 715 |
| 23 | Shear-wave Elastography Improves the Specificity of Breast US: The BE1 Multinational Study of 939 Masses | Radiology | 2012 | 714 |
| 24 | Large-scale association analyses identify host factors influencing human gut microbiome composition | Nature Genetics | 2021 | 676 |
| 25 | Anticytoplasmic Autoantibodies: Their Immunodiagnostic Value in Wegener Granulomatosis | Annals of Internal Medicine | 1989 | 654 |
| 26 | East Asian monsoon climate during the Late Pleistocene: high-resolution sediment records from the South China Sea | Marine Geology | 1999 | 636 |
| 27 | Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci | Nature Genetics | 2016 | 617 |
| 28 | The IASP classification of chronic pain for ICD-11: chronic neuropathic pain | Pain | 2019 | 571 |
| 29 | Structure and dynamics of the fast lithium ion conductor “Li7La3Zr2O12” | Physical Chemistry Chemical Physics | 2011 | 559 |
| 30 | Design of a potent and selective inhibitor of the intermediate-conductance Ca2+-activated K+ channel, IKCa1: A potential immunosuppressant | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 553 |
| 31 | A catalog of genetic loci associated with kidney function from analyses of a million individuals | Nature Genetics | 2019 | 549 |
| 32 | Biodiversity at multiple trophic levels is needed for ecosystem multifunctionality | Nature | 2016 | 526 |
| 33 | Interaction of alkylamines with different types of layered compounds | Solid State Ionics | 1986 | 506 |
| 34 | Ecosystem service potentials, flows and demands-concepts for spatial localisation, indication and quantification | Landscape Online | 0 | 506 |
| 35 | Interleukin-6 Family Cytokines | Cold Spring Harbor Perspectives in Biology | 2018 | 501 |
| 36 | Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis | Nature Genetics | 2016 | 494 |
| 37 | Randomized, Open-Label Phase II Study Evaluating the Efficacy and Safety of Talimogene Laherparepvec in Combination With Ipilimumab Versus Ipilimumab Alone in Patients With Advanced, Unresectable Melanoma | Journal of Clinical Oncology | 2018 | 483 |
| 38 | Sequence and cultivation study of Muribaculaceae reveals novel species, host preference, and functional potential of this yet undescribed family | Microbiome | 2019 | 481 |
| 39 | ZnO tetrapod materials for functional applications | Materials Today | 2018 | 473 |
| 40 | Interleukin-6 and its receptors: A highly regulated and dynamic system | Cytokine | 2014 | 443 |
| 41 | Interleukin-6: designing specific therapeutics for a complex cytokine | Nature Reviews Drug Discovery | 2018 | 440 |
| 42 | Epstein-Barr virus-associated Hodgkin's disease: Epidemiologic characteristics in international data | | 1997 | 424 |
| 43 | Microgrid Stability Definitions, Analysis, and Examples | IEEE Transactions on Power Systems | 2020 | 422 |
| 44 | Patent applications and subsequent changes of performance: evidence from time-series cross-section analyses on the firm level | Research Policy | 2001 | 417 |
| 45 | Consumer versus resource control of species diversity and ecosystem functioning | Nature | 2002 | 417 |
| 46 | Pathology of Genetically Engineered Mouse Models of Pancreatic Exocrine Cancer: Consensus Report and Recommendations | Cancer Research | 2006 | 401 |
| 47 | Crop pests and predators exhibit inconsistent responses to surrounding landscape composition | Proceedings of the National Academy of Sciences of the United States of America | 2018 | 401 |
| 48 | Monoclonal antibodies directed against the calcium binding protein parvalbumin | Cell Calcium | 1988 | 383 |
| 49 | Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases | JAMA Oncology | 2017 | 376 |
| 50 | Validation of the Aura Microwave Limb Sounder temperature and geopotential height measurements | Journal of Geophysical Research | 2008 | 370 |
