| # | Title | Journal | Year | Citations |
|---|
| 1 | Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy | JAMA - Journal of the American Medical Association | 2020 | 4,411 |
| 2 | Isolation and Characterization of Tumorigenic, Stem-like Neural Precursors from Human Glioblastoma | Cancer Research | 2004 | 2,318 |
| 3 | Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria | Nature Immunology | 2001 | 2,239 |
| 4 | Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease | Nature Genetics | 2009 | 2,155 |
| 5 | Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease | Nature Genetics | 2011 | 1,708 |
| 6 | Large-scale association analysis identifies new risk loci for coronary artery disease | Nature Genetics | 2013 | 1,439 |
| 7 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 8 | QSAR Modeling: Where Have You Been? Where Are You Going To? | Journal of Medicinal Chemistry | 2014 | 1,401 |
| 9 | Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document | Journal of Hypertension | 2009 | 1,236 |
| 10 | Microbial biosurfactants production, applications and future potential | Applied Microbiology and Biotechnology | 2010 | 1,193 |
| 11 | Risk Factors Associated With Mortality Among Patients With COVID-19 in Intensive Care Units in Lombardy, Italy | JAMA Internal Medicine | 2020 | 1,165 |
| 12 | 2007 ESH-ESC Practice Guidelines for the Management of Arterial Hypertension | Journal of Hypertension | 2007 | 1,152 |
| 13 | Dendritic cells directly trigger NK cell functions: Cross-talk relevant in innate anti-tumor immune responses in vivo | Nature Medicine | 1999 | 984 |
| 14 | Prevention and Management of Chemotherapy-Induced Peripheral Neuropathy in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline | Journal of Clinical Oncology | 2014 | 976 |
| 15 | Generation of Gut-Homing IgA-Secreting B Cells by Intestinal Dendritic Cells | Science | 2006 | 910 |
| 16 | Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome | Science | 2013 | 900 |
| 17 | Panethnic Differences in Blood Pressure in Europe: A Systematic Review and Meta-Analysis | PLoS ONE | 2016 | 882 |
| 18 | Multiple common variants for celiac disease influencing immune gene expression | Nature Genetics | 2010 | 871 |
| 19 | CD14 Controls the LPS-Induced Endocytosis of Toll-like Receptor 4 | Cell | 2011 | 765 |
| 20 | Thyroid cancer mortality and incidence: A global overview | International Journal of Cancer | 2015 | 763 |
| 21 | Common variants associated with plasma triglycerides and risk for coronary artery disease | Nature Genetics | 2013 | 754 |
| 22 | Influence of spring and autumn phenological transitions on forest ecosystem productivity | Philosophical Transactions of the Royal Society B: Biological Sciences | 2010 | 751 |
| 23 | Discrimination between Alzheimer Dementia and Controls by Automated Analysis of Multicenter FDG PET | NeuroImage | 2002 | 714 |
| 24 | European Society of Hypertension guidelines for blood pressure monitoring at home: a summary report of the Second International Consensus Conference on Home Blood Pressure Monitoring | Journal of Hypertension | 2008 | 707 |
| 25 | New insights into the genetic etiology of Alzheimer’s disease and related dementias | Nature Genetics | 2022 | 700 |
| 26 | Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study | Blood | 2010 | 685 |
| 27 | Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease | Nature Genetics | 2011 | 682 |
| 28 | Endothelial function and dysfunction. Part II: Association with cardiovascular risk factors and diseases. A statement by the Working Group on Endothelins and Endothelial Factors of the European Society of Hypertension* | Journal of Hypertension | 2005 | 637 |
| 29 | Hypertension | Nature Reviews Disease Primers | 2018 | 636 |
| 30 | Recommendations for Increasing Replicability in Psychology | European Journal of Personality | 2013 | 625 |
| 31 | Management of high blood pressure in children and adolescents: recommendations of the European Society of Hypertension | Journal of Hypertension | 2009 | 620 |
| 32 | Cosmology and fundamental physics with the Euclid satellite | Living Reviews in Relativity | 2018 | 602 |
| 33 | Mental health of prisoners: prevalence, adverse outcomes, and interventions | Lancet Psychiatry,the | 2016 | 592 |
| 34 | Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain | Development (Cambridge) | 2004 | 587 |
| 35 | A simple role for BDNF in learning and memory? | Frontiers in Molecular Neuroscience | 2010 | 583 |
| 36 | Unintended Consequences of Machine Learning in Medicine | JAMA - Journal of the American Medical Association | 2017 | 574 |
| 37 | Large-area luminescent solar concentrators based on ‘Stokes-shift-engineered’ nanocrystals in a mass-polymerized PMMA matrix | Nature Photonics | 2014 | 568 |
| 38 | A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicentre randomised trial | Lancet, The | 2007 | 547 |
| 39 | Benchmark Analysis of Representative Deep Neural Network Architectures | IEEE Access | 2018 | 533 |
| 40 | ESVS Guidelines. Invasive Treatment for Carotid Stenosis: Indications, Techniques | European Journal of Vascular and Endovascular Surgery | 2009 | 532 |
| 41 | APOE and Alzheimer disease: a major gene with semi-dominant inheritance | Molecular Psychiatry | 2011 | 529 |
| 42 | Melanoma contains CD133 and ABCG2 positive cells with enhanced tumourigenic potential | European Journal of Cancer | 2007 | 523 |
| 43 | Follow-up of Blood-Pressure Lowering and Glucose Control in Type 2 Diabetes | New England Journal of Medicine | 2014 | 520 |
| 44 | Pathophysiology of COVID-19-associated acute respiratory distress syndrome: a multicentre prospective observational study | Lancet Respiratory Medicine,the | 2020 | 516 |
| 45 | Timing of India‐Asia collision: Geological, biostratigraphic, and palaeomagnetic constraints | Journal of Geophysical Research | 2010 | 505 |
| 46 | Regulation of OPA1 processing and mitochondrial fusion by m-AAA protease isoenzymes and OMA1 | Journal of Cell Biology | 2009 | 500 |
| 47 | Synthesis of the H-cluster framework of iron-only hydrogenase | Nature | 2005 | 498 |
| 48 | Selective transport of internalized antigens to the cytosol for MHC class I presentation in dendritic cells | Nature Cell Biology | 1999 | 496 |
| 49 | The Replication Recipe: What makes for a convincing replication? | Journal of Experimental Social Psychology | 2014 | 492 |
| 50 | Alcohol drinking and colorectal cancer risk: an overall and dose–response meta-analysis of published studies | Annals of Oncology | 2011 | 487 |
