| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 2 | Management of obesity | Lancet, The | 2016 | 715 |
| 3 | Interdisciplinary European Guidelines on Metabolic and Bariatric Surgery | Obesity Surgery | 2014 | 498 |
| 4 | Clinical efficacy and safety of achieving very low LDL-cholesterol concentrations with the PCSK9 inhibitor evolocumab: a prespecified secondary analysis of the FOURIER trial | Lancet, The | 2017 | 487 |
| 5 | Red wine polyphenols modulate fecal microbiota and reduce markers of the metabolic syndrome in obese patients | Food and Function | 2016 | 262 |
| 6 | Obesity changes the human gut mycobiome | Scientific Reports | 2015 | 231 |
| 7 | The pig as an animal model for human pathologies: A proteomics perspective | Proteomics - Clinical Applications | 2014 | 213 |
| 8 | Definition and Diagnostic Criteria for Sarcopenic Obesity: ESPEN and EASO Consensus Statement | Obesity Facts | 2022 | 209 |
| 9 | Role of astrocytes, microglia, and tanycytes in brain control of systemic metabolism | Nature Neuroscience | 2019 | 200 |
| 10 | Critical appraisal of definitions and diagnostic criteria for sarcopenic obesity based on a systematic review | Clinical Nutrition | 2020 | 193 |
| 11 | Obesity: The Gateway to Ill Health - an EASO Position Statement on a Rising Public Health, Clinical and Scientific Challenge in Europe | Obesity Facts | 2013 | 180 |
| 12 | Circulating lipopolysaccharide-binding protein (LBP) as a marker of obesity-related insulin resistance | International Journal of Obesity | 2012 | 164 |
| 13 | Safety and Efficacy of Low Blood Pressures Among Patients With Diabetes | Journal of the American College of Cardiology | 2012 | 164 |
| 14 | Integrated care pathways for airway diseases (AIRWAYS-ICPs) | European Respiratory Journal | 2014 | 154 |
| 15 | Clinical characteristics and evaluation of LDL-cholesterol treatment of the Spanish Familial Hypercholesterolemia Longitudinal Cohort Study (SAFEHEART) | Lipids in Health and Disease | 2011 | 121 |
| 16 | Fibroblast growth factor 15/19 (FGF15/19) protects from diet-induced hepatic steatosis: development of an FGF19-based chimeric molecule to promote fatty liver regeneration | Gut | 2017 | 118 |
| 17 | Definition and diagnostic criteria for sarcopenic obesity: ESPEN and EASO consensus statement | Clinical Nutrition | 2022 | 117 |
| 18 | Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors | Biological Psychiatry | 2022 | 114 |
| 19 | Contribution of macronutrients to obesity: implications for precision nutrition | Nature Reviews Endocrinology | 2020 | 113 |
| 20 | Grape-seed procyanidins modulate inflammation on human differentiated adipocytes in vitro | Cytokine | 2009 | 110 |
| 21 | Efficacy and safety of alirocumab in insulin‐treated individuals with type 1 or type 2 diabetes and high cardiovascular risk: The ODYSSEY DM‐INSULIN randomized trial | Diabetes, Obesity and Metabolism | 2017 | 105 |
| 22 | The Gene Expression of the Main Lipogenic Enzymes is Downregulated in Visceral Adipose Tissue of Obese Subjects | Obesity | 2010 | 99 |
| 23 | Metabolomics Unveils Urinary Changes in Subjects with Metabolic Syndrome following 12-Week Nut Consumption | Journal of Proteome Research | 2011 | 99 |
| 24 | Circulating irisin levels and coronary heart disease: association with future acute coronary syndrome and major adverse cardiovascular events | International Journal of Obesity | 2015 | 95 |
| 25 | An EASO Position Statement on Multidisciplinary Obesity Management in Adults | Obesity Facts | 2014 | 74 |
| 26 | Gut Microbiota Interacts with Markers of Adipose Tissue Browning, Insulin Action and Plasma Acetate in Morbid Obesity | Molecular Nutrition and Food Research | 2018 | 73 |
| 27 | Food patterns and the prevention of depression | Proceedings of the Nutrition Society | 2016 | 71 |
| 28 | Semaglutide as a promising antiobesity drug | Obesity Reviews | 2019 | 71 |
| 29 | Low social interactions in eating disorder patients in childhood and adulthood: A multi-centre European case control study | Journal of Health Psychology | 2013 | 70 |
| 30 | Maternal and Foetal Health Implications of Vitamin D Status during Pregnancy | Annals of Nutrition and Metabolism | 2018 | 69 |
| 31 | The gut microbiota modulates both browning of white adipose tissue and the activity of brown adipose tissue | Reviews in Endocrine and Metabolic Disorders | 2019 | 68 |
| 32 | Long-Term Coffee Consumption Is Associated with Decreased Incidence of New-Onset Hypertension: A Dose–Response Meta-Analysis | Nutrients | 2017 | 62 |
| 33 | The protein type within a hypocaloric diet affects obesity-related inflammation: The RESMENA project | Nutrition | 2014 | 59 |
| 34 | The metabolic and vascular protective effects of olive (Olea europaea L.) leaf extract in diet-induced obesity in mice are related to the amelioration of gut microbiota dysbiosis and to its immunomodulatory properties | Pharmacological Research | 2019 | 59 |
| 35 | Non-selective beta-blockers impair global circulatory homeostasis and renal function in cirrhotic patients with refractory ascites | Journal of Hepatology | 2020 | 58 |
| 36 | Higher baseline irisin concentrations are associated with greater reductions in glycemia and insulinemia after weight loss in obese subjects | Nutrition and Diabetes | 2014 | 57 |
| 37 | Effect of lipid-lowering treatment in cardiovascular disease prevalence in familial hypercholesterolemia | Atherosclerosis | 2019 | 55 |
| 38 | Thyroid hormone levels predict the change in body weight: a prospective study | European Journal of Clinical Investigation | 2011 | 53 |
| 39 | Therapeutic approaches in the improvement of cognitive performance in Down syndrome | Progress in Brain Research | 2012 | 53 |
| 40 | Insulin resistance in prepubertal obese children correlates with sex-dependent early onset metabolomic alterations | International Journal of Obesity | 2016 | 51 |
| 41 | The complement system is dysfunctional in metabolic disease: Evidences in plasma and adipose tissue from obese and insulin resistant subjects | Seminars in Cell and Developmental Biology | 2019 | 51 |
| 42 | Oxidative Stress and DNA Damage in Obesity-Related Tumorigenesis | Advances in Experimental Medicine and Biology | 2014 | 49 |
| 43 | Polyphenol rich olive oils improve lipoprotein particle atherogenic ratios and subclasses profile: A randomized, crossover, controlled trial | Molecular Nutrition and Food Research | 2016 | 47 |
| 44 | Preoperative Circulating Succinate Levels as a Biomarker for Diabetes Remission After Bariatric Surgery | Diabetes Care | 2019 | 47 |
| 45 | Current standing of plant derived flavonoids as an antidepressant | Food and Chemical Toxicology | 2018 | 46 |
| 46 | Higher Protein Diets Consumed Ad Libitum Improve Cardiovascular Risk Markers in Children of Overweight Parents from Eight European Countries | Journal of Nutrition | 2013 | 44 |
| 47 | Sexual Dimorphism of Adipose and Hepatic Aquaglyceroporins in Health and Metabolic Disorders | Frontiers in Endocrinology | 2015 | 44 |
| 48 | Effects of Dairy Product Consumption on Height and Bone Mineral Content in Children: A Systematic Review of Controlled Trials | Advances in Nutrition | 2019 | 44 |
| 49 | A low‐protein diet induces body weight loss and browning of subcutaneous white adipose tissue through enhanced expression of hepatic fibroblast growth factor 21 (FGF21) | Molecular Nutrition and Food Research | 2017 | 42 |
| 50 | Endogenous Retroelement Activation by Epigenetic Therapy Reverses the Warburg Effect and Elicits Mitochondrial-Mediated Cancer Cell Death | Cancer Discovery | 2021 | 42 |
