| # | Title | Journal | Year | Citations |
|---|
| 1 | SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor | Cell | 2020 | 16,161 |
| 2 | The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research | PLoS Biology | 2020 | 2,209 |
| 3 | DNA methylation-based classification of central nervous system tumours | Nature | 2018 | 1,872 |
| 4 | The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research | Experimental Physiology | 2020 | 1,300 |
| 5 | 2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus | Arthritis and Rheumatology | 2019 | 1,098 |
| 6 | COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options | Cardiovascular Research | 2020 | 1,074 |
| 7 | Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0 | PLoS Biology | 2020 | 1,069 |
| 8 | The EAACI/GA²LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria | Allergy: European Journal of Allergy and Clinical Immunology | 2018 | 1,008 |
| 9 | Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19 | Nature Neuroscience | 2021 | 991 |
| 10 | Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function | Science | 2017 | 978 |
| 11 | Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group | Molecular Psychiatry | 2016 | 850 |
| 12 | SARS ‐CoV‐2 receptor ACE 2 and TMPRSS 2 are primarily expressed in bronchial transient secretory cells | EMBO Journal | 2020 | 812 |
| 13 | Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) | European Journal of Immunology | 2019 | 766 |
| 14 | 2019 European League Against Rheumatism/American College of Rheumatology classification criteria for systemic lupus erythematosus | Annals of the Rheumatic Diseases | 2019 | 759 |
| 15 | Hosts and Sources of Endemic Human Coronaviruses | Advances in Virus Research | 2018 | 756 |
| 16 | New insights into the genetic etiology of Alzheimer’s disease and related dementias | Nature Genetics | 2022 | 700 |
| 17 | Variability in the analysis of a single neuroimaging dataset by many teams | Nature | 2020 | 634 |
| 18 | Myocarditis and inflammatory cardiomyopathy: current evidence and future directions | Nature Reviews Cardiology | 2021 | 589 |
| 19 | Formation of new chromatin domains determines pathogenicity of genomic duplications | Nature | 2016 | 582 |
| 20 | The future of cystic fibrosis care: a global perspective | Lancet Respiratory Medicine,the | 2020 | 573 |
| 21 | Changes to taxonomy and the International Code of Virus Classification and Nomenclature ratified by the International Committee on Taxonomy of Viruses (2018) | Archives of Virology | 2018 | 567 |
| 22 | The Banff 2015 Kidney Meeting Report: Current Challenges in Rejection Classification and Prospects for Adopting Molecular Pathology | American Journal of Transplantation | 2017 | 551 |
| 23 | The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research* | Journal of Cerebral Blood Flow and Metabolism | 2020 | 546 |
| 24 | Expansion of the Human Phenotype Ontology (HPO) knowledge base and resources | Nucleic Acids Research | 2019 | 539 |
| 25 | OpenMS: a flexible open-source software platform for mass spectrometry data analysis | Nature Methods | 2016 | 537 |
| 26 | Guidelines for the use of flow cytometry and cell sorting in immunological studies* | European Journal of Immunology | 2017 | 505 |
| 27 | Gasdermin D plays a vital role in the generation of neutrophil extracellular traps | Science Immunology | 2018 | 486 |
| 28 | The Banff 2019 Kidney Meeting Report (I): Updates on and clarification of criteria for T cell– and antibody-mediated rejection | American Journal of Transplantation | 2020 | 437 |
| 29 | Perturbation-response genes reveal signaling footprints in cancer gene expression | Nature Communications | 2018 | 436 |
| 30 | The dynamic nature of senescence in cancer | Nature Cell Biology | 2019 | 394 |
| 31 | Nafamostat Mesylate Blocks Activation of SARS-CoV-2: New Treatment Option for COVID-19 | Antimicrobial Agents and Chemotherapy | 2020 | 394 |
| 32 | The international EAACI/GA²LEN/EuroGuiDerm/APAAACI guideline for the definition, classification, diagnosis, and management of urticaria | Allergy: European Journal of Allergy and Clinical Immunology | 2022 | 392 |
| 33 | Estimating infectiousness throughout SARS-CoV-2 infection course | Science | 2021 | 389 |
| 34 | International Exercise Recommendations in Older Adults (ICFSR): Expert Consensus Guidelines | Journal of Nutrition, Health and Aging | 2021 | 384 |
| 35 | Circulating plasma concentrations of angiotensin-converting enzyme 2 in men and women with heart failure and effects of renin–angiotensin–aldosterone inhibitors | European Heart Journal | 2020 | 381 |
| 36 | Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform | Nature | 2020 | 377 |
| 37 | Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2 | Nature | 2020 | 370 |
| 38 | The international WAO/EAACI guideline for the management of hereditary angioedema—The 2017 revision and update | Allergy: European Journal of Allergy and Clinical Immunology | 2018 | 365 |
| 39 | ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries | Translational Psychiatry | 2020 | 365 |
| 40 | cIMPACT‐NOW update 6: new entity and diagnostic principle recommendations of the cIMPACT‐Utrecht meeting on future CNS tumor classification and grading | Brain Pathology | 2020 | 363 |
| 41 | 2021 European Society of Hypertension practice guidelines for office and out-of-office blood pressure measurement | Journal of Hypertension | 2021 | 349 |
| 42 | Ethical guidelines for publishing in the Journal of Cachexia, Sarcopenia and Muscle: update 2019 | Journal of Cachexia, Sarcopenia and Muscle | 2019 | 341 |
| 43 | Cardiovascular and kidney outcomes with finerenone in patients with type 2 diabetes and chronic kidney disease: the FIDELITY pooled analysis | European Heart Journal | 2022 | 341 |
| 44 | Periprosthetic joint infection: current concepts and outlook | EFORT Open Reviews | 2019 | 338 |
| 45 | Magnetic Resonance Perfusion or Fractional Flow Reserve in Coronary Disease | New England Journal of Medicine | 2019 | 326 |
| 46 | The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research | British Journal of Pharmacology | 2020 | 326 |
| 47 | Inflammation – Cause or Consequence of Heart Failure or Both? | Current Heart Failure Reports | 2017 | 324 |
| 48 | Human Anti-fungal Th17 Immunity and Pathology Rely on Cross-Reactivity against Candida albicans | Cell | 2019 | 321 |
| 49 | Benchmarking single-cell RNA-sequencing protocols for cell atlas projects | Nature Biotechnology | 2020 | 313 |
| 50 | Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience | Acta Neuropathologica | 2018 | 308 |
