| # | Title | Journal | Year | Citations |
|---|
| 1 | Protected Carotid-Artery Stenting versus Endarterectomy in High-Risk Patients | New England Journal of Medicine | 2004 | 2,729 |
| 2 | Predicting survival after liver transplantation in patients with hepatocellular carcinoma beyond the Milan criteria: a retrospective, exploratory analysis | Lancet Oncology, The | 2009 | 1,920 |
| 3 | Clinical practice guidelines for antimicrobial prophylaxis in surgery | American Journal of Health-System Pharmacy | 2013 | 1,643 |
| 4 | Mucins in cancer: protection and control of the cell surface | Nature Reviews Cancer | 2004 | 1,580 |
| 5 | APD3: the antimicrobial peptide database as a tool for research and education | Nucleic Acids Research | 2016 | 1,537 |
| 6 | Daptomycin versus Standard Therapy for Bacteremia and Endocarditis Caused byStaphylococcus aureus | New England Journal of Medicine | 2006 | 1,347 |
| 7 | Clinical Practice Guidelines for the Management of Patients with Histoplasmosis: 2007 Update by the Infectious Diseases Society of America | Clinical Infectious Diseases | 2007 | 1,148 |
| 8 | Nanogels as Pharmaceutical Carriers: Finite Networks of Infinite Capabilities | Angewandte Chemie - International Edition | 2009 | 1,134 |
| 9 | IL-8 Directly Enhanced Endothelial Cell Survival, Proliferation, and Matrix Metalloproteinases Production and Regulated Angiogenesis | Journal of Immunology | 2003 | 1,132 |
| 10 | Cell proliferation in carcinogenesis | Science | 1990 | 1,062 |
| 11 | Treatment of the Crigler–Najjar Syndrome Type I with Hepatocyte Transplantation | New England Journal of Medicine | 1998 | 1,008 |
| 12 | Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancer | Nature Medicine | 2007 | 1,000 |
| 13 | Use of Transesophageal Echocardiography to Guide Cardioversion in Patients with Atrial Fibrillation | New England Journal of Medicine | 2001 | 889 |
| 14 | How Do We Define Cure of Diabetes? | Diabetes Care | 2009 | 852 |
| 15 | APD2: the updated antimicrobial peptide database and its application in peptide design | Nucleic Acids Research | 2009 | 816 |
| 16 | Iron Oxide Nanoparticles for Sustained Delivery of Anticancer Agents | Molecular Pharmaceutics | 2005 | 814 |
| 17 | Clinical Practice Guidelines for Antimicrobial Prophylaxis in Surgery | Surgical Infections | 2013 | 809 |
| 18 | Endocytic delivery of lipocalin-siderophore-iron complex rescues the kidney from ischemia-reperfusion injury | Journal of Clinical Investigation | 2005 | 796 |
| 19 | Transient Ischemic Attack — Proposal for a New Definition | New England Journal of Medicine | 2002 | 750 |
| 20 | CD133 expression is not restricted to stem cells, and both CD133+ and CD133– metastatic colon cancer cells initiate tumors | Journal of Clinical Investigation | 2008 | 736 |
| 21 | Long-Term Results of Carotid Stenting versus Endarterectomy in High-Risk Patients | New England Journal of Medicine | 2008 | 732 |
| 22 | Nanosized cationic hydrogels for drug delivery: preparation, properties and interactions with cells | Advanced Drug Delivery Reviews | 2002 | 705 |
| 23 | APD: the Antimicrobial Peptide Database | Nucleic Acids Research | 2004 | 651 |
| 24 | Effect of Eritoran, an Antagonist of MD2-TLR4, on Mortality in Patients With Severe Sepsis | JAMA - Journal of the American Medical Association | 2013 | 625 |
| 25 | Muc5b is required for airway defence | Nature | 2014 | 617 |
| 26 | Identification of an antimalarial synthetic trioxolane drug development candidate | Nature | 2004 | 584 |
| 27 | Development and Validation of a Risk Calculator for Prediction of Cardiac Risk After Surgery | Circulation | 2011 | 584 |
| 28 | Pluronic® block copolymers for overcoming drug resistance in cancer | Advanced Drug Delivery Reviews | 2002 | 579 |
| 29 | Treatment of Rheumatoid Arthritis with Methotrexate Alone, Sulfasalazine and Hydroxychloroquine, or a Combination of All Three Medications | New England Journal of Medicine | 1996 | 566 |
| 30 | Guidelines for evaluation of new fever in critically ill adult patients: 2008 update from the American College of Critical Care Medicine and the Infectious Diseases Society of America | Critical Care Medicine | 2008 | 549 |
| 31 | The Effect of Combined Estrogen and Progesterone Hormone Replacement Therapy on Disease Activity in Systemic Lupus Erythematosus: A Randomized Trial | Annals of Internal Medicine | 2005 | 539 |
| 32 | Dextran sodium sulfate colitis murine model: An indispensable tool for advancing our understanding of inflammatory bowel diseases pathogenesis | World Journal of Gastroenterology | 2017 | 533 |
| 33 | Ceftriaxone-Resistant Salmonella Infection Acquired by a Child from Cattle | New England Journal of Medicine | 2000 | 481 |
| 34 | Free Radical Theory of Aging: An Update: Increasing the Functional Life Span | Annals of the New York Academy of Sciences | 2006 | 478 |
| 35 | Sonic Hedgehog Promotes Desmoplasia in Pancreatic Cancer | Clinical Cancer Research | 2008 | 460 |
| 36 | Review of emerging surgical robotic technology | Surgical Endoscopy and Other Interventional Techniques | 2018 | 455 |
| 37 | Acyclovir for Prevention of Cytomegalovirus Infection and Disease after Allogeneic Marrow Transplantation | New England Journal of Medicine | 1988 | 444 |
| 38 | Multi-institutional clinical experience with the Calypso System in localization and continuous, real-time monitoring of the prostate gland during external radiotherapy | International Journal of Radiation Oncology Biology Physics | 2007 | 444 |
| 39 | Effectiveness and Safety of the Awakening and Breathing Coordination, Delirium Monitoring/Management, and Early Exercise/Mobility Bundle* | Critical Care Medicine | 2014 | 442 |
| 40 | Nanogels: An overview of properties, biomedical applications and obstacles to clinical translation | Journal of Controlled Release | 2016 | 441 |
| 41 | 2003 Report of the Intestine Transplant Registry | Annals of Surgery | 2005 | 430 |
| 42 | A Prospective, Randomized Trial of Laparoscopic Polytetrafluoroethylene (PTFE) Patch Repair vs Simple Cruroplasty for Large Hiatal Hernia | Archives of Surgery | 2002 | 419 |
| 43 | Murine Models to Evaluate Novel and Conventional Therapeutic Strategies for Cancer | American Journal of Pathology | 2007 | 419 |
| 44 | A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns | Nature | 2016 | 418 |
| 45 | Acetaminophen Toxicity in an Urban County Hospital | New England Journal of Medicine | 1997 | 415 |
| 46 | Human Antimicrobial Peptides and Proteins | Pharmaceuticals | 2014 | 402 |
| 47 | Effect of Epidural Anesthesia and Analgesia on Perioperative Outcome | Annals of Surgery | 2001 | 395 |
| 48 | Movement Variability and the Use of Nonlinear Tools: Principles to Guide Physical Therapist Practice | Physical Therapy | 2009 | 394 |
| 49 | The Safety and Efficacy of Infliximab in Moderate to Severe Chronic Obstructive Pulmonary Disease | American Journal of Respiratory and Critical Care Medicine | 2007 | 393 |
| 50 | Aphasia With Nonhemorrhagic Lesions in the Basal Ganglia and Internal Capsule | Archives of Neurology | 1982 | 389 |
