| # | Title | Journal | Year | Citations |
|---|
| 1 | EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update | Annals of the Rheumatic Diseases | 2017 | 3,366 |
| 2 | Clinical Practice Guidelines for Clostridium difficile Infection in Adults: 2010 Update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA) | Infection Control and Hospital Epidemiology | 2010 | 2,716 |
| 3 | 10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer | New England Journal of Medicine | 2016 | 2,101 |
| 4 | Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: a report of the International Myeloma Working Group | British Journal of Haematology | 2003 | 1,887 |
| 5 | Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA) | Clinical Infectious Diseases | 2018 | 1,695 |
| 6 | Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease | Nature Genetics | 2011 | 1,685 |
| 7 | Addition of docetaxel, zoledronic acid, or both to first-line long-term hormone therapy in prostate cancer (STAMPEDE): survival results from an adaptive, multiarm, multistage, platform randomised controlled trial | Lancet, The | 2016 | 1,570 |
| 8 | Ibrutinib versus Ofatumumab in Previously Treated Chronic Lymphoid Leukemia | New England Journal of Medicine | 2014 | 1,427 |
| 9 | British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults | Gut | 2019 | 1,353 |
| 10 | Ibrutinib as Initial Therapy for Patients with Chronic Lymphocytic Leukemia | New England Journal of Medicine | 2015 | 1,261 |
| 11 | Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes | Nature Genetics | 2018 | 1,124 |
| 12 | 2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus | Arthritis and Rheumatology | 2019 | 1,098 |
| 13 | The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms | Leukemia | 2022 | 1,023 |
| 14 | Postdischarge symptoms and rehabilitation needs in survivors of COVID‐19 infection: A cross‐sectional evaluation | Journal of Medical Virology | 2021 | 996 |
| 15 | Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA) | Clinical Infectious Diseases | 2018 | 900 |
| 16 | Update on the Paris Classification of Superficial Neoplastic Lesions in the Digestive Tract | Endoscopy | 2005 | 806 |
| 17 | Capecitabine compared with observation in resected biliary tract cancer (BILCAP): a randomised, controlled, multicentre, phase 3 study | Lancet Oncology, The | 2019 | 773 |
| 18 | Complications following autologous bone graft harvesting from the iliac crest and using the RIA: A systematic review | Injury | 2011 | 669 |
| 19 | Randomized Trial of Complete Versus Lesion-Only Revascularization in Patients Undergoing Primary Percutaneous Coronary Intervention for STEMI and Multivessel Disease | Journal of the American College of Cardiology | 2015 | 662 |
| 20 | A consensus protocol for the standardization of cerebrospinal fluid collection and biobanking | Neurology | 2009 | 653 |
| 21 | The prevalence and outcomes of frailty in older cancer patients: a systematic review | Annals of Oncology | 2015 | 647 |
| 22 | Magnetic Resonance Imaging for the Detection, Localisation, and Characterisation of Prostate Cancer: Recommendations from a European Consensus Meeting | European Urology | 2011 | 642 |
| 23 | Rates of Circumferential Resection Margin Involvement Vary Between Surgeons and Predict Outcomes in Rectal Cancer Surgery | Annals of Surgery | 2002 | 591 |
| 24 | Association of Postoperative High-Sensitivity Troponin Levels With Myocardial Injury and 30-Day Mortality Among Patients Undergoing Noncardiac Surgery | JAMA - Journal of the American Medical Association | 2017 | 579 |
| 25 | Autologous Hematopoietic Stem Cell Transplantation vs Intravenous Pulse Cyclophosphamide in Diffuse Cutaneous Systemic Sclerosis | JAMA - Journal of the American Medical Association | 2014 | 566 |
| 26 | Alemtuzumab Compared With Chlorambucil As First-Line Therapy for Chronic Lymphocytic Leukemia | Journal of Clinical Oncology | 2007 | 533 |
| 27 | Therapeutic drug monitoring (TDM) of antifungal agents: guidelines from the British Society for Medical Mycology | Journal of Antimicrobial Chemotherapy | 2014 | 525 |
| 28 | Anti-interleukin-17A monoclonal antibody secukinumab in treatment of ankylosing spondylitis: a randomised, double-blind, placebo-controlled trial | Lancet, The | 2013 | 518 |
| 29 | Systematic approach to sonographic evaluation of the pelvis in women with suspected endometriosis, including terms, definitions and measurements: a consensus opinion from the International Deep Endometriosis Analysis (IDEA) group | Ultrasound in Obstetrics and Gynecology | 2016 | 503 |
| 30 | Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling | Nature Genetics | 2014 | 490 |
| 31 | The Southampton Consensus Guidelines for Laparoscopic Liver Surgery | Annals of Surgery | 2018 | 488 |
| 32 | Prenatal exome sequencing analysis in fetal structural anomalies detected by ultrasonography (PAGE): a cohort study | Lancet, The | 2019 | 443 |
| 33 | Arsenic trioxide and all-trans retinoic acid treatment for acute promyelocytic leukaemia in all risk groups (AML17): results of a randomised, controlled, phase 3 trial | Lancet Oncology, The | 2015 | 433 |
| 34 | Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study | The Lancet Gastroenterology and Hepatology | 2019 | 431 |
| 35 | A Nonlinear Mapping Approach to Stain Normalization in Digital Histopathology Images Using Image-Specific Color Deconvolution | IEEE Transactions on Biomedical Engineering | 2014 | 430 |
| 36 | Guidelines for the diagnosis and antibiotic treatment of endocarditis in adults: a report of the Working Party of the British Society for Antimicrobial Chemotherapy | Journal of Antimicrobial Chemotherapy | 2012 | 428 |
| 37 | European League Against Rheumatism recommendations for the management of psoriatic arthritis with pharmacological therapies | Annals of the Rheumatic Diseases | 2012 | 405 |
| 38 | Second-line FOLFOX chemotherapy versus active symptom control for advanced biliary tract cancer (ABC-06): a phase 3, open-label, randomised, controlled trial | Lancet Oncology, The | 2021 | 396 |
| 39 | The adverse effects of obesity on conception and implantation | Reproduction | 2010 | 390 |
| 40 | Long-term clinical outcomes in survivors of severe acute respiratory syndrome and Middle East respiratory syndrome coronavirus outbreaks after hospitalisation or ICU admission: A systematic review and meta-analysis | Journal of Rehabilitation Medicine | 2020 | 389 |
| 41 | The Modern Abdominoperineal Excision | Annals of Surgery | 2005 | 384 |
| 42 | A No-Prophylaxis Platelet-Transfusion Strategy for Hematologic Cancers | New England Journal of Medicine | 2013 | 384 |
| 43 | Defining active sacroiliitis on MRI for classification of axial spondyloarthritis: update by the ASAS MRI working group | Annals of the Rheumatic Diseases | 2016 | 383 |
| 44 | Prevalence of depression and anxiety in patients with cystic fibrosis and parent caregivers: results of The International Depression Epidemiological Study across nine countries | Thorax | 2014 | 372 |
| 45 | Diagnostic criteria for monoclonal B-cell lymphocytosis | British Journal of Haematology | 2005 | 360 |
| 46 | Azacitidine augments expansion of regulatory T cells after allogeneic stem cell transplantation in patients with acute myeloid leukemia (AML) | Blood | 2012 | 355 |
| 47 | Distinct genetic architectures for syndromic and nonsyndromic congenital heart defects identified by exome sequencing | Nature Genetics | 2016 | 351 |
| 48 | High Rate of Recurrent De Novo Mutations in Developmental and Epileptic Encephalopathies | American Journal of Human Genetics | 2017 | 337 |
| 49 | Rapid pathogen detection by metagenomic next-generation sequencing of infected body fluids | Nature Medicine | 2021 | 329 |
| 50 | Guidelines on the management of abnormal liver blood tests | Gut | 2018 | 320 |
