| # | Title | Journal | Year | Citations |
|---|
| 1 | Imatinib Compared with Interferon and Low-Dose Cytarabine for Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia | New England Journal of Medicine | 2003 | 3,227 |
| 2 | Five-Year Follow-up of Patients Receiving Imatinib for Chronic Myeloid Leukemia | New England Journal of Medicine | 2006 | 3,212 |
| 3 | Development, cytokine profile and function of human interleukin 17–producing helper T cells | Nature Immunology | 2007 | 1,795 |
| 4 | The putative forkhead transcription factor FOXL2 is mutated in blepharophimosis/ptosis/epicanthus inversus syndrome | Nature Genetics | 2001 | 886 |
| 5 | European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia | Leukemia | 2020 | 875 |
| 6 | Bortezomib, thalidomide, and dexamethasone with or without daratumumab before and after autologous stem-cell transplantation for newly diagnosed multiple myeloma (CASSIOPEIA): a randomised, open-label, phase 3 study | Lancet, The | 2019 | 665 |
| 7 | Efficacy and safety of selective internal radiotherapy with yttrium-90 resin microspheres compared with sorafenib in locally advanced and inoperable hepatocellular carcinoma (SARAH): an open-label randomised controlled phase 3 trial | Lancet Oncology, The | 2017 | 595 |
| 8 | A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk | Nature Genetics | 2009 | 540 |
| 9 | An Index Combining Respiratory Rate and Oxygenation to Predict Outcome of Nasal High-Flow Therapy | American Journal of Respiratory and Critical Care Medicine | 2019 | 477 |
| 10 | Long-term prognostic significance of early molecular response to imatinib in newly diagnosed chronic myeloid leukemia: an analysis from the International Randomized Study of Interferon and STI571 (IRIS) | Blood | 2010 | 440 |
| 11 | Clinical practice guidelines for the prevention and treatment of EGFR inhibitor-associated dermatologic toxicities | Supportive Care in Cancer | 2011 | 374 |
| 12 | The European Brain Injury Consortium Survey of Head Injuries | Acta Neurochirurgica | 1999 | 344 |
| 13 | Skin Inflammation Induced by the Synergistic Action of IL-17A, IL-22, Oncostatin M, IL-1α, and TNF-α Recapitulates Some Features of Psoriasis | Journal of Immunology | 2010 | 274 |
| 14 | Sclerotherapy with or without Octreotide for Acute Variceal Bleeding | New England Journal of Medicine | 1995 | 267 |
| 15 | A signature of circulating inflammatory proteins and development of end-stage renal disease in diabetes | Nature Medicine | 2019 | 260 |
| 16 | Mechanisms of stent thrombosis analysed by optical coherence tomography: insights from the national PESTO French registry | European Heart Journal | 2016 | 243 |
| 17 | Predictive Factors of Long-term Compliance With Nasal Continuous Positive Airway Pressure Treatment in Sleep Apnea Syndrome | Chest | 1994 | 231 |
| 18 | Early molecular response predicts outcomes in patients with chronic myeloid leukemia in chronic phase treated with frontline nilotinib or imatinib | Blood | 2014 | 231 |
| 19 | Prognosis of long-term survival considering disease-specific death in patients with chronic myeloid leukemia | Leukemia | 2016 | 225 |
| 20 | Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy for Gastric Cancer With Peritoneal Metastases (CYTO-CHIP study): A Propensity Score Analysis | Journal of Clinical Oncology | 2019 | 218 |
| 21 | Prevalence and impact of frailty on mortality in elderly ICU patients: a prospective, multicenter, observational study | Intensive Care Medicine | 2014 | 210 |
| 22 | Clinical practice guidelines for the prevention and treatment of acute and late radiation reactions from the MASCC Skin Toxicity Study Group | Supportive Care in Cancer | 2013 | 203 |
| 23 | Recombinant Coagulation Factor VIIa in Major Liver Resection | Anesthesiology | 2005 | 201 |
| 24 | Heart Failure Care in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis | PLoS Medicine | 2014 | 198 |
| 25 | Favorable long-term follow-up results over 6 years for response, survival, and safety with imatinib mesylate therapy in chronic-phase chronic myeloid leukemia after failure of interferon-α treatment | Blood | 2008 | 195 |
| 26 | Phenotypical, Biological, and Molecular Heterogeneity of 5α-Reductase Deficiency: An Extensive International Experience of 55 Patients | Journal of Clinical Endocrinology and Metabolism | 2011 | 192 |
| 27 | Stratifying Type 2 Diabetes Cases by BMI Identifies Genetic Risk Variants in LAMA1 and Enrichment for Risk Variants in Lean Compared to Obese Cases | PLoS Genetics | 2012 | 190 |
| 28 | Efficacy and safety of dasatinib in imatinib-resistant or -intolerant patients with chronic myeloid leukemia in blast phase | Leukemia | 2008 | 189 |
| 29 | Effect of Postextubation High-Flow Nasal Oxygen With Noninvasive Ventilation vs High-Flow Nasal Oxygen Alone on Reintubation Among Patients at High Risk of Extubation Failure | JAMA - Journal of the American Medical Association | 2019 | 188 |
| 30 | Efficacy and Safety of Deep Brain Stimulation in Tourette Syndrome | JAMA Neurology | 2018 | 186 |
| 31 | The role for high flow nasal cannula as a respiratory support strategy in adults: a clinical practice guideline | Intensive Care Medicine | 2020 | 185 |
| 32 | Radiotherapy or Autologous Stem-Cell Transplantation for Primary CNS Lymphoma in Patients 60 Years of Age and Younger: Results of the Intergroup ANOCEF-GOELAMS Randomized Phase II PRECIS Study | Journal of Clinical Oncology | 2019 | 184 |
| 33 | Accuracy of a continuous noninvasive hemoglobin monitor in intensive care unit patients* | Critical Care Medicine | 2011 | 182 |
| 34 | Predictors of Pain Relief Following Spinal Cord Stimulation in Chronic Back and Leg Pain and Failed Back Surgery Syndrome: A Systematic Review and Meta‐Regression Analysis | Pain Practice | 2014 | 182 |
| 35 | Monoclonal gammopathy of clinical significance: a novel concept with therapeutic implications | Blood | 2018 | 173 |
| 36 | Preoperative chemoradiotherapy versus preoperative radiotherapy in rectal cancer patients: assessment of acute toxicity and treatment compliance | European Journal of Cancer | 2004 | 168 |
| 37 | Comparison of long-term outcome between anti-Jo1- and anti-PL7/PL12 positive patients with antisynthetase syndrome | Autoimmunity Reviews | 2012 | 167 |
| 38 | Safety and efficacy of aneurysm treatment with WEB in the cumulative population of three prospective, multicenter series | Journal of NeuroInterventional Surgery | 2018 | 162 |
| 39 | Sirolimus Versus Cyclosporine in Kidney Recipients Receiving Thymoglobulin®, Mycophenolate Mofetil and a 6‐Month Course of Steroids | American Journal of Transplantation | 2007 | 160 |
| 40 | Sequential Application of Oxygen Therapy Via High-Flow Nasal Cannula and Noninvasive Ventilation in Acute Respiratory Failure: An Observational Pilot Study | Respiratory Care | 2015 | 158 |
| 41 | Epidemiology of Helicobacter pylori infection | Helicobacter | 2017 | 158 |
| 42 | High-dose chemotherapy with autologous stem cell transplantation as first-line therapy for primary CNS lymphoma in patients younger than 60 years: a multicenter phase II study of the GOELAMS group | Bone Marrow Transplantation | 2006 | 154 |
| 43 | Evaluation of 16S rRNA Gene PCR Sensitivity and Specificity for Diagnosis of Prosthetic Joint Infection: a Prospective Multicenter Cross-Sectional Study | Journal of Clinical Microbiology | 2014 | 154 |
| 44 | SCN9A Mutations Define Primary Erythermalgia as a Neuropathic Disorder of Voltage Gated Sodium Channels | Journal of Investigative Dermatology | 2005 | 153 |
| 45 | Comparative PRKAR1A genotype-phenotype analyses in humans with Carney complex and prkar1a haploinsufficient mice | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 152 |
| 46 | X-linked lissencephaly with absent corpus callosum and ambiguous genitalia (XLAG): Clinical, magnetic resonance imaging, and neuropathological findings | Annals of Neurology | 2002 | 149 |
| 47 | Comparison of Intrapulmonary and Systemic Pharmacokinetics of Colistin Methanesulfonate (CMS) and Colistin after Aerosol Delivery and Intravenous Administration of CMS in Critically Ill Patients | Antimicrobial Agents and Chemotherapy | 2014 | 148 |
| 48 | Prognosis and Histopathologic Features in Papillary Tumors of the Pineal Region | Journal of Neuropathology and Experimental Neurology | 2006 | 142 |
| 49 | The Value of the “Worst” Computed Tomographic Scan in Clinical Studies of Moderate and Severe Head Injury | Neurosurgery | 2000 | 136 |
| 50 | A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes | Diabetes | 2018 | 136 |
