| # | Title | Journal | Year | Citations |
|---|
| 1 | Prognostic Value of Fractional Flow Reserve | Journal of the American College of Cardiology | 2014 | 513 |
| 2 | Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer | Nature Communications | 2018 | 293 |
| 3 | Applications of Machine Learning in Human Microbiome Studies: A Review on Feature Selection, Biomarker Identification, Disease Prediction and Treatment | Frontiers in Microbiology | 2021 | 157 |
| 4 | Impact of COVID-19 Pandemic on Mechanical Reperfusion for Patients With STEMI | Journal of the American College of Cardiology | 2020 | 154 |
| 5 | Cardiopoietic cell therapy for advanced ischemic heart failure: results at 39 weeks of the prospective, randomized, double blind, sham-controlled CHART-1 clinical trial | European Heart Journal | 2017 | 148 |
| 6 | Microbiota y diabetes mellitus tipo 2 | Endocrinologia Y Nutricion: Organo De La Sociedad Espanola De Endocrinologia Y Nutricion | 2016 | 111 |
| 7 | Prevalence of Atrial Fibrillation in Spain. OFRECE Study Results | Revista Espanola De Cardiologia (English Ed ) | 2014 | 98 |
| 8 | Dual Therapy With Darunavir and Ritonavir Plus Lamivudine vs Triple Therapy With Darunavir and Ritonavir Plus Tenofovir Disoproxil Fumarate and Emtricitabine or Abacavir and Lamivudine for Maintenance of Human Immunodeficiency Virus Type 1 Viral Suppression: Randomized, Open-Label, Noninferiority DUAL-GESIDA 8014-RIS-EST45 Trial | Clinical Infectious Diseases | 2017 | 88 |
| 9 | Clinical Impact of Baseline Right Bundle Branch Block in Patients Undergoing Transcatheter Aortic Valve Replacement | JACC: Cardiovascular Interventions | 2017 | 87 |
| 10 | Sorafenib and bevacizumab combination targeted therapy in advanced neuroendocrine tumour: A phase II study of Spanish Neuroendocrine Tumour Group (GETNE0801) | European Journal of Cancer | 2013 | 84 |
| 11 | Obesity and survival in operable breast cancer patients treated with adjuvant anthracyclines and taxanes according to pathological subtypes: a pooled analysis | Breast Cancer Research | 2013 | 80 |
| 12 | Parenteral Nutrition–Associated Hyperglycemia in Non–Critically Ill Inpatients Increases the Risk of In-Hospital Mortality (Multicenter Study) | Diabetes Care | 2013 | 78 |
| 13 | Prognostic Impact of Hyponatremia and Hypernatremia in COVID-19 Pneumonia. A HOPE-COVID-19 (Health Outcome Predictive Evaluation for COVID-19) Registry Analysis | Frontiers in Endocrinology | 2020 | 74 |
| 14 | Epirubicin–cyclophosphamide adjuvant chemotherapy plus tamoxifen administered concurrently versus sequentially: randomized phase III trial in postmenopausal node-positive breast cancer patients. A GEICAM 9401 study | Annals of Oncology | 2004 | 69 |
| 15 | Maintenance treatment with Pegylated liposomal doxorubicin versus observation following induction chemotherapy for metastatic breast cancer: GEICAM 2001-01 study | Breast Cancer Research and Treatment | 2010 | 69 |
| 16 | Gut microbiota and type 2 diabetes mellitus | Endocrinología Y Nutrición (English Edition) | 2016 | 64 |
| 17 | Haemorrhoidectomy: Randomised Controlled Clinical Trial of Ligasure ® Compared with Milligan-Morgan Operation | The European Journal of Surgery | 2002 | 55 |
| 18 | Changes in Oxidative Stress and Insulin Resistance in Morbidly Obese Patients After Bariatric Surgery | Obesity Surgery | 2010 | 55 |
| 19 | Improvement of breast cancer relapse prediction in high risk intervals using artificial neural networks | Breast Cancer Research and Treatment | 2005 | 53 |
| 20 | Statistical and Machine Learning Techniques in Human Microbiome Studies: Contemporary Challenges and Solutions | Frontiers in Microbiology | 2021 | 51 |
| 21 | Prospective registry of symptomatic severe aortic stenosis in octogenarians: a need for intervention | Journal of Internal Medicine | 2014 | 49 |
| 22 | Antiplatelet therapy and outcome in COVID-19: the Health Outcome Predictive Evaluation Registry | Heart | 2022 | 49 |
| 23 | Multiple sclerosis prevalence in Malaga, Southern Spain estimated by the capture–recapture method | Multiple Sclerosis Journal | 2012 | 47 |
| 24 | The Ibero-American transcatheter aortic valve implantation registry with the CoreValve prosthesis. Early and long-term results | International Journal of Cardiology | 2013 | 43 |
| 25 | H. pylori eradication with antibiotic treatment causes changes in glucose homeostasis related to modifications in the gut microbiota | PLoS ONE | 2019 | 43 |
| 26 | Relationship between myostatin and irisin in type 2 diabetes mellitus: a compensatory mechanism to an unfavourable metabolic state? | Endocrine | 2016 | 40 |
| 27 | Comparison of Initial Mechanical Properties of 4 Hamstring Graft Femoral Fixation Systems Using Nonpermanent Hardware for Anterior Cruciate Ligament Reconstruction: An In Vitro Animal Study | Arthroscopy - Journal of Arthroscopic and Related Surgery | 2006 | 37 |
| 28 | Safety, long-term outcomes and predictors of recurrence after first-line combined endoepicardial ventricular tachycardia substrate ablation in arrhythmogenic cardiomyopathy. Impact of arrhythmic substrate distribution pattern. A prospective multicentre study | Europace | 2016 | 37 |
| 29 | Does angina the week before protect against first myocardial infarction in elderly patients? | American Journal of Cardiology | 2001 | 36 |
| 30 | Augmentation technique for partial ACL ruptures using semitendinosus tendon in the over-the-top position | Knee Surgery, Sports Traumatology, Arthroscopy | 2010 | 36 |
| 31 | Prevalencia de angina estable en España. Resultados del estudio OFRECE | Revista Espanola De Cardiologia | 2015 | 36 |
| 32 | Clinical Outcomes and Prognosis Markers of Patients With Liver Disease Undergoing Transcatheter Aortic Valve Replacement | Circulation: Cardiovascular Interventions | 2018 | 36 |
| 33 | Perioperative and Periprocedural Management of Antithrombotic Therapy: Consensus Document of SEC, SEDAR, SEACV, SECTCV, AEC, SECPRE, SEPD, SEGO, SEHH, SETH, SEMERGEN, SEMFYC, SEMG, SEMICYUC, SEMI, SEMES, SEPAR, SENEC, SEO, SEPA, SERVEI, SECOT and AEU | Revista Espanola De Cardiologia (English Ed ) | 2018 | 35 |
| 34 | Oxidative stress and metabolic changes after continuous positive airway pressure treatment according to previous metabolic disorders in sleep apnea-hypopnea syndrome patients | Translational Research | 2009 | 34 |
| 35 | Comorbidity and intervention in octogenarians with severe symptomatic aortic stenosis | International Journal of Cardiology | 2015 | 34 |
| 36 | Measurement of Fractional Flow Reserve to Assess Moderately Severe Coronary Lesions: Correlation with Dobutamine Stress Echocardiography | Journal of Interventional Cardiology | 2001 | 33 |
| 37 | A phase Ib study of sonidegib (LDE225), an oral small molecule inhibitor of smoothened or Hedgehog pathway, in combination with docetaxel in triple negative advanced breast cancer patients: GEICAM/2012–12 (EDALINE) study | Investigational New Drugs | 2019 | 33 |
| 38 | 18F-fluoromisonidazole PET and Activity of Neoadjuvant Nintedanib in Early HER2-Negative Breast Cancer: A Window-of-Opportunity Randomized Trial | Clinical Cancer Research | 2017 | 32 |
| 39 | Targeted therapy of metastatic breast cancer | Clinical and Translational Oncology | 2009 | 31 |
| 40 | Close-looped graft suturing improves mechanical properties of interference screw fixation in ACL reconstruction | Knee Surgery, Sports Traumatology, Arthroscopy | 2013 | 31 |
| 41 | Design and rationale of the QUAZAR Lower-Risk MDS (AZA-MDS-003) trial: a randomized phase 3 study of CC-486 (oral azacitidine) plus best supportive care vs placebo plus best supportive care in patients with IPSS lower-risk myelodysplastic syndromes and poor prognosis due to red blood cell transfusion–dependent anemia and thrombocytopenia | BMC Hematology | 2016 | 31 |
| 42 | COVID-19 anosmia and gustatory symptoms as a prognosis factor: a subanalysis of the HOPE COVID-19 (Health Outcome Predictive Evaluation for COVID-19) registry | Infection | 2021 | 31 |
| 43 | Genetic polymorphisms in folate pathway enzymes, DRD4 and GSTM1 are related to temporomandibular disorder | BMC Medical Genetics | 2011 | 30 |
| 44 | Impact of COVID-19 pandemic and diabetes on mechanical reperfusion in patients with STEMI: insights from the ISACS STEMI COVID 19 Registry | Cardiovascular Diabetology | 2020 | 30 |
| 45 | Complications in medial meniscus suture: a cadaveric study | Knee Surgery, Sports Traumatology, Arthroscopy | 2007 | 29 |
| 46 | SELNET clinical practice guidelines for soft tissue sarcoma and GIST | Cancer Treatment Reviews | 2022 | 29 |
| 47 | Prognostic impact of MGMT promoter methylation and MGMT and CD133 expression in colorectal adenocarcinoma | BMC Cancer | 2014 | 28 |
| 48 | Prevalence and distribution of hepatitis C virus genotypes in Spain during the 2000‐2015 period (the GEHEP 005 study) | Journal of Viral Hepatitis | 2017 | 28 |
| 49 | Effect of CPAP on Oxidative Stress and Circulating Progenitor Cell Levels in Sleep Patients With Apnea-Hypopnea Syndrome | Respiratory Care | 2011 | 27 |
| 50 | BIM-23A760 influences key functional endpoints in pituitary adenomas and normal pituitaries: molecular mechanisms underlying the differential response in adenomas | Scientific Reports | 2017 | 27 |
