Pembrolizumab in patients with advanced hepatocellular carcinoma previously treated with sorafenib (KEYNOTE-224): a non-randomised, open-label phase 2 trial | Lancet Oncology, The | 2018 | 1.1K |
Lack of placental transfer of certolizumab pegol during pregnancy: results from CRIB, a prospective, postmarketing, pharmacokinetic study | Annals of the Rheumatic Diseases | 2018 | 184 |
Improvement in Overall Survival With Carfilzomib, Lenalidomide, and Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma | Journal of Clinical Oncology | 2018 | 164 |
International, evidence-based consensus treatment guidelines for idiopathic multicentric Castleman disease | Blood | 2018 | 127 |
2018 EHRA expert consensus statement on lead extraction: recommendations on definitions, endpoints, research trial design, and data collection requirements for clinical scientific studies and registries: endorsed by APHRS/HRS/LAHRS | Europace | 2018 | 126 |
The NLRP6 Inflammasome Recognizes Lipoteichoic Acid and Regulates Gram-Positive Pathogen Infection | Cell | 2018 | 121 |
Sirolimus is efficacious in treatment for extensive and/or complex slow-flow vascular malformations: a monocentric prospective phase II study | Orphanet Journal of Rare Diseases | 2018 | 91 |
Intravascular hemolysis activates complement via cell-free heme and heme-loaded microvesicles | JCI Insight | 2018 | 87 |
Inflammasomes in Tissue Damages and Immune Disorders After Trauma | Frontiers in Immunology | 2018 | 83 |
Effects of Long-term Norfloxacin Therapy in Patients With Advanced Cirrhosis | Gastroenterology | 2018 | 74 |
The European Registry for Patients with Mechanical Circulatory Support (EUROMACS) of the European Association for Cardio-Thoracic Surgery (EACTS): second report | European Journal of Cardio-thoracic Surgery | 2018 | 71 |
Early Cognitive, Structural, and Microstructural Changes in Presymptomatic C9orf72 Carriers Younger Than 40 Years | JAMA Neurology | 2018 | 68 |
Oncogenetic mutations combined with MRD improve outcome prediction in pediatric T-cell acute lymphoblastic leukemia | Blood | 2018 | 63 |
4-year survival and outcomes after cessation of pembrolizumab (pembro) after 2-years in patients (pts) with ipilimumab (ipi)-naive advanced melanoma in KEYNOTE-006. | Journal of Clinical Oncology | 2018 | 60 |
Antitumour activity of pembrolizumab in advanced mucosal melanoma: a post-hoc analysis of KEYNOTE-001, 002, 006 | British Journal of Cancer | 2018 | 60 |
Management of endometriosis: CNGOF/HAS clinical practice guidelines - Short version | Journal of Gynecology Obstetrics and Human Reproduction | 2018 | 51 |
Practice guidelines for the management of adult community-acquired urinary tract infections | Médecine Et Maladies Infectieuses | 2018 | 50 |
Recommendations for managing PD-1 blockade in the context of allogeneic HCT in Hodgkin lymphoma: taming a necessary evil | Blood | 2018 | 49 |
Outcomes 7 Years After Infliximab Withdrawal for Patients With Crohn's Disease in Sustained Remission | Clinical Gastroenterology and Hepatology | 2018 | 47 |
Annular closure in lumbar microdiscectomy for prevention of reherniation: a randomized clinical trial | Spine Journal | 2018 | 44 |
Assessing the cost-effectiveness of hepatitis C screening strategies in France | Journal of Hepatology | 2018 | 40 |
Susceptibility Vessel Sign in the ASTER Trial: Higher Recanalization Rate and More Favourable Clinical Outcome after First Line Stent Retriever Compared to Contact Aspiration | Journal of Stroke | 2018 | 38 |
A dietary flavone confers communicable protection against colitis through NLRP6 signaling independently of inflammasome activation | Mucosal Immunology | 2018 | 37 |
Melanoma metabolism contributes to the cellular responses to MAPK/ERK pathway inhibitors | Biochimica Et Biophysica Acta - General Subjects | 2018 | 36 |
Wiedemann-Steiner syndrome as a major cause of syndromic intellectual disability: A study of 33 French cases | Clinical Genetics | 2018 | 33 |