| Defeating Alzheimer's disease and other dementias: a priority for European science and society | Lancet Neurology, The | 2016 | 921 |
| Carfilzomib and dexamethasone versus bortezomib and dexamethasone for patients with relapsed or refractory multiple myeloma (ENDEAVOR): a randomised, phase 3, open-label, multicentre study | Lancet Oncology, The | 2016 | 576 |
| Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects | Immunity | 2016 | 376 |
| Bromodomain inhibitor OTX015 in patients with lymphoma or multiple myeloma: a dose-escalation, open-label, pharmacokinetic, phase 1 study | Lancet Haematology,the | 2016 | 270 |
| Standard Definitions and Common Data Elements for Clinical Trials in Patients With Alcoholic Hepatitis: Recommendation From the NIAAA Alcoholic Hepatitis Consortia | Gastroenterology | 2016 | 223 |
| Recent progress in genetics, epigenetics and metagenomics unveils the pathophysiology of human obesity | Clinical Science | 2016 | 202 |
| A novel Alzheimer disease locus located near the gene encoding tau protein | Molecular Psychiatry | 2016 | 175 |
| A Critical Analysis of the Current Knowledge of Surgical Anatomy of the Prostate Related to Optimisation of Cancer Control and Preservation of Continence and Erection in Candidates for Radical Prostatectomy: An Update | European Urology | 2016 | 149 |
| Editor's Choice - Subsequent Results for Arch Aneurysm Repair with Inner Branched Endografts | European Journal of Vascular and Endovascular Surgery | 2016 | 130 |
| Rare Inherited and De Novo CNVs Reveal Complex Contributions to ASD Risk in Multiplex Families | American Journal of Human Genetics | 2016 | 125 |
| Nocardia Infection in Solid Organ Transplant Recipients: A Multicenter European Case-control Study | Clinical Infectious Diseases | 2016 | 122 |
| Risk of Symptomatic Intracerebral Hemorrhage After Intravenous Thrombolysis in Patients With Acute Ischemic Stroke and High Cerebral Microbleed Burden: A Meta-analysis | JAMA Neurology | 2016 | 120 |
| Safety of Oral Propranolol for the Treatment of Infantile Hemangioma: A Systematic Review | Pediatrics | 2016 | 101 |
| Adherence to Antihypertensive Treatment and the Blood Pressure-Lowering Effects of Renal Denervation in the Renal Denervation for Hypertension (DENERHTN) Trial | Circulation | 2016 | 98 |
| Methotrexate Is Not Superior to Placebo for Inducing Steroid-Free Remission, but Induces Steroid-Free Clinical Remission in a Larger Proportion of Patients With Ulcerative Colitis | Gastroenterology | 2016 | 85 |
| Treacher Collins syndrome: a clinical and molecular study based on a large series of patients | Genetics in Medicine | 2016 | 78 |
| Long-Term Outcomes Among Participants in the WEGENT Trial of Remission-Maintenance Therapy for Granulomatosis With Polyangiitis (Wegener's) or Microscopic Polyangiitis | Arthritis and Rheumatology | 2016 | 78 |
| A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease | Science Translational Medicine | 2016 | 77 |
| Preclinical Development of a MicroRNA-Based Therapy for Elderly Patients With Myocardial Infarction | Journal of the American College of Cardiology | 2016 | 75 |
| Joint and tendon involvement predict disease progression in systemic sclerosis: a EUSTAR prospective study | Annals of the Rheumatic Diseases | 2016 | 68 |
| Multicentre experience using daclatasvir and sofosbuvir to treat hepatitis C recurrence - The ANRS CUPILT study | Journal of Hepatology | 2016 | 63 |
| Phase I Population Pharmacokinetic Assessment of the Oral Bromodomain Inhibitor OTX015 in Patients with Haematologic Malignancies | Clinical Pharmacokinetics | 2016 | 61 |
| Respiratory manifestations of eosinophilic granulomatosis with polyangiitis (Churg-Strauss) | European Respiratory Journal | 2016 | 61 |
| Haematological spectrum and genotype-phenotype correlations in nine unrelated families with RUNX1 mutations from the French network on inherited platelet disorders | Orphanet Journal of Rare Diseases | 2016 | 59 |
| Research Progresses in Understanding the Pathophysiology of Moyamoya Disease | Cerebrovascular Diseases | 2016 | 57 |
