| # | Title | Journal | Year | Citations |
|---|
| 1 | Rituximab maintenance for 2 years in patients with high tumour burden follicular lymphoma responding to rituximab plus chemotherapy (PRIMA): a phase 3, randomised controlled trial | Lancet, The | 2011 | 957 |
| 2 | Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling | Nature Genetics | 2014 | 490 |
| 3 | KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron | Nature Genetics | 2012 | 281 |
| 4 | Slow walking speed and cardiovascular death in well functioning older adults: prospective cohort study | BMJ: British Medical Journal | 2009 | 274 |
| 5 | Dose-dense rituximab-CHOP compared with standard rituximab-CHOP in elderly patients with diffuse large B-cell lymphoma (the LNH03-6B study): a randomised phase 3 trial | Lancet Oncology, The | 2013 | 257 |
| 6 | Only four genes (EDA1, EDAR, EDARADD, and WNT10A) account for 90% of hypohidrotic/anhidrotic ectodermal dysplasia cases | Human Mutation | 2011 | 240 |
| 7 | Efficient strategy for the molecular diagnosis of intellectual disability using targeted high-throughput sequencing | Journal of Medical Genetics | 2014 | 229 |
| 8 | Mutations within the MGC4607 Gene Cause Cerebral Cavernous Malformations | American Journal of Human Genetics | 2004 | 219 |
| 9 | Epidemiology and pathophysiology of adulthood-onset thrombotic microangiopathy with severe ADAMTS13 deficiency (thrombotic thrombocytopenic purpura): a cross-sectional analysis of the French national registry for thrombotic microangiopathy | Lancet Haematology,the | 2016 | 218 |
| 10 | The Meckel-Gruber Syndrome Gene, MKS3, Is Mutated in Joubert Syndrome | American Journal of Human Genetics | 2007 | 217 |
| 11 | KIF7 mutations cause fetal hydrolethalus and acrocallosal syndromes | Nature Genetics | 2011 | 203 |
| 12 | Immunosuppressive therapy is more effective than interferon in neuromyelitis optica | Multiple Sclerosis Journal | 2007 | 190 |
| 13 | The world-wide burden of musculoskeletal diseases: a systematic analysis of the World Health Organization Burden of Diseases Database | Annals of the Rheumatic Diseases | 2019 | 184 |
| 14 | Inappropriate medication use and risk of falls – A prospective study in a large community-dwelling elderly cohort | BMC Geriatrics | 2009 | 165 |
| 15 | Effect of Systematic Intensive Care Unit Triage on Long-term Mortality Among Critically Ill Elderly Patients in France | JAMA - Journal of the American Medical Association | 2017 | 160 |
| 16 | Effect of Statin Therapy on Mortality in Patients With Ventilator-Associated Pneumonia | JAMA - Journal of the American Medical Association | 2013 | 155 |
| 17 | The landscape of epilepsy-related GATOR1 variants | Genetics in Medicine | 2019 | 137 |
| 18 | Hospital-acquired pneumonia in ICU | Anaesthesia, Critical Care & Pain Medicine | 2018 | 135 |
| 19 | Impact of Norovirus/Sapovirus-Related Diarrhea in Renal Transplant Recipients Hospitalized for Diarrhea | Transplantation | 2011 | 130 |
| 20 | High-dose cytarabine does not overcome the adverse prognostic value of CDKN2A and TP53 deletions in mantle cell lymphoma | Blood | 2015 | 130 |
| 21 | Postural disorders in Parkinson’s disease | Neurophysiologie Clinique | 2008 | 129 |
| 22 | Proton Pump Inhibitors vs. Histamine 2 Receptor Antagonists for Stress-Related Mucosal Bleeding Prophylaxis in Critically Ill Patients: A Meta-Analysis | American Journal of Gastroenterology | 2012 | 128 |
| 23 | Methotrexate therapy for rheumatoid arthritis: clinical practice guidelines based on published evidence and expert opinion | Joint Bone Spine | 2006 | 126 |
| 24 | Management of severe traumatic brain injury (first 24 hours) | Anaesthesia, Critical Care & Pain Medicine | 2018 | 126 |
| 25 | Mutations in signal recognition particle SRP54 cause syndromic neutropenia with Shwachman-Diamond–like features | Journal of Clinical Investigation | 2017 | 126 |
| 26 | A Cross-Sectional and Longitudinal Study of the Relationship Between Walking Speed and Cognitive Function in Community-Dwelling Elderly People | Journals of Gerontology - Series A Biological Sciences and Medical Sciences | 2009 | 125 |
| 27 | Spectrum of the Mutations in Bernard-Soulier Syndrome | Human Mutation | 2014 | 124 |
| 28 | A simplified frailty scale predicts outcomes in transplant-ineligible patients with newly diagnosed multiple myeloma treated in the FIRST (MM-020) trial | Leukemia | 2020 | 122 |
| 29 | Correlates of regular fish consumption in French elderly community dwellers: data from the Three-City study | European Journal of Clinical Nutrition | 2005 | 112 |
| 30 | White matter lesions volume and motor performances in the elderly | Annals of Neurology | 2009 | 109 |
| 31 | Thymic Neuroendocrine Tumors in Multiple Endocrine Neoplasia Type 1: A Comparative Study on 21 Cases Among a Series of 761 MEN1 from the GTE (Groupe des Tumeurs Endocrines) | World Journal of Surgery | 2009 | 109 |
| 32 | C-reactive protein and procalcitonin for the early detection of anastomotic leakage after elective colorectal surgery: Pilot study in 100 patients | Journal of Visceral Surgery | 2012 | 106 |
| 33 | Pressure ulcer risk factors in persons with spinal cord injury Part 2: the chronic stage | Spinal Cord | 2009 | 105 |
| 34 | Pediatric Evans syndrome is associated with a high frequency of potentially damaging variants in immune genes | Blood | 2019 | 102 |
| 35 | Frequency and risk factors of potentially inappropriate medication use in a community-dwelling elderly population: results from the 3C Study | European Journal of Clinical Pharmacology | 2005 | 101 |
| 36 | Immunochemical faecal occult blood tests are superior to guaiac-based tests for the detection of colorectal neoplasms | European Journal of Cancer | 2008 | 97 |
| 37 | New insights into genotype–phenotype correlation for GLI3 mutations | European Journal of Human Genetics | 2015 | 97 |
| 38 | Stroke associated with giant cell arteritis: a population-based study | Journal of Neurology, Neurosurgery and Psychiatry | 2015 | 95 |
| 39 | Cirrhotic patients with portal hypertension-related bleeding and an indication for early-TIPS: A large multicentre audit with real-life results | Journal of Hepatology | 2018 | 92 |
| 40 | Neonatal outcome associated with singleton birth at 34-41 weeks of gestation | International Journal of Epidemiology | 2010 | 91 |
| 41 | Staphylococcus aureus Bloodstream Infection and Endocarditis - A Prospective Cohort Study | PLoS ONE | 2015 | 90 |
| 42 | Differential association of calreticulin type 1 and type 2 mutations with myelofibrosis and essential thrombocytemia: relevance for disease evolution | Leukemia | 2015 | 88 |
| 43 | Eculizumab discontinuation in children and adults with atypical hemolytic-uremic syndrome: a prospective multicenter study | Blood | 2021 | 87 |
| 44 | Outcome in AN adult patients: A 13-year follow-up in 484 patients | Diabetes and Metabolism | 2011 | 86 |
| 45 | Potential Roles of Peroxisomes in Alzheimer's Disease and in Dementia of the Alzheimer's Type | Journal of Alzheimer's Disease | 2012 | 86 |
| 46 | Profile of the Risk of Death After Septic Shock in the Present Era | Critical Care Medicine | 2013 | 84 |
| 47 | The VIRSTA score, a prediction score to estimate risk of infective endocarditis and determine priority for echocardiography in patients with Staphylococcus aureus bacteremia | Journal of Infection | 2016 | 82 |
| 48 | Guidelines on the management of infectious encephalitis in adults | Médecine Et Maladies Infectieuses | 2017 | 82 |
| 49 | Higher risk of death among MEN1 patients with mutations in the JunD interacting domain: a Groupe d’étude des Tumeurs Endocrines (GTE) cohort study | Human Molecular Genetics | 2013 | 81 |
| 50 | Clinical features and course of refractory anemia with ring sideroblasts associated with marked thrombocytosis | Haematologica | 2012 | 79 |
