Detection of circulating tumor DNA in early- and late-stage human malignancies | Science Translational Medicine | 2014 | 2.7K |
Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab | Journal of Clinical Oncology | 2014 | 1.7K |
Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy | Clinical Cancer Research | 2014 | 1.7K |
A draft map of the human proteome | Nature | 2014 | 1.5K |
Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs | JAMA - Journal of the American Medical Association | 2014 | 1K |
Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): a multicentre, randomised, double-blind, phase 3 trial | Lancet Oncology, The | 2014 | 982 |
Hypoxia and the extracellular matrix: drivers of tumour metastasis | Nature Reviews Cancer | 2014 | 785 |
Cancer epigenetics: tumor heterogeneity, plasticity of stem-like states, and drug resistance | Molecular Cell | 2014 | 583 |
Blood-based analyses of cancer: circulating tumor cells and circulating tumor DNA | Cancer Discovery | 2014 | 473 |
Functional normalization of 450k methylation array data improves replication in large cancer studies | Genome Biology | 2014 | 435 |
Eradication of metastatic mouse cancers resistant to immune checkpoint blockade by suppression of myeloid-derived cells | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 426 |
A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme | Autophagy | 2014 | 343 |
Breathing new life into immunotherapy: review of melanoma, lung and kidney cancer | Nature Reviews Clinical Oncology | 2014 | 311 |
Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers | Oncotarget | 2014 | 299 |
Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma | Nature Genetics | 2014 | 296 |
Cytoreductive nephrectomy in patients with synchronous metastases from renal cell carcinoma: results from the International Metastatic Renal Cell Carcinoma Database Consortium | European Urology | 2014 | 282 |
Detection of cancer DNA in plasma of patients with early-stage breast cancer | Clinical Cancer Research | 2014 | 280 |
Association of the autoimmune disease scleroderma with an immunologic response to cancer | Science | 2014 | 278 |
American Cancer Society prostate cancer survivorship care guidelines | Ca-A Cancer Journal for Clinicians | 2014 | 258 |
Pancreatic adenocarcinoma, version 2.2014: featured updates to the NCCN guidelines | Journal of the National Comprehensive Cancer Network: JNCCN | 2014 | 254 |
Characterization of HPV and host genome interactions in primary head and neck cancers | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 229 |
Tumour-infiltrating Gr-1+ myeloid cells antagonize senescence in cancer | Nature | 2014 | 211 |
Association between class III obesity (BMI of 40-59 kg/m2) and mortality: a pooled analysis of 20 prospective studies | PLoS Medicine | 2014 | 208 |
Intratumoral injection of Clostridium novyi-NT spores induces antitumor responses | Science Translational Medicine | 2014 | 202 |
Three-dimensional cell migration does not follow a random walk | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 197 |