| # | Title | Journal | Year | Citations |
|---|
| 1 | Principles and practical application of the receiver-operating characteristic analysis for diagnostic tests | Preventive Veterinary Medicine | 2000 | 1,573 |
| 2 | The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N‐methyl‐aspartate | British Journal of Pharmacology | 1983 | 1,263 |
| 3 | Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists | Science | 1988 | 1,184 |
| 4 | Chronic Peroxisome Proliferator-activated Receptor γ (PPARγ) Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct from Classic Brown Adipocytes | Journal of Biological Chemistry | 2010 | 1,131 |
| 5 | The causes of reduced fertility with cryopreserved semen | Animal Reproduction Science | 2000 | 997 |
| 6 | Recent developments and concepts in the cryopreservation of spermatozoa and the assessment of their post-thawing function | Reproduction, Fertility and Development | 1995 | 828 |
| 7 | Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: an open-label, phase 2, dose-escalation study | Lancet, The | 2011 | 803 |
| 8 | The Lancet Countdown on health and climate change: from 25 years of inaction to a global transformation for public health | Lancet, The | 2018 | 802 |
| 9 | Sources of toxoplasma infection in pregnant women: European multicentre case-control study Commentary: Congenital toxoplasmosis---further thought for food | BMJ: British Medical Journal | 2000 | 787 |
| 10 | Moving in the Anthropocene: Global reductions in terrestrial mammalian movements | Science | 2018 | 783 |
| 11 | Zoonosis emergence linked to agricultural intensification and environmental change | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 729 |
| 12 | Immunosenescence: emerging challenges for an ageing population | Immunology | 2007 | 711 |
| 13 | Evidence for involvement ofN-methylaspartate receptors in ‘wind-up’ of class 2 neurones in the dorsal horn of the rat | Brain Research | 1987 | 643 |
| 14 | Polyunsaturated Fatty Acids in Male and Female Reproduction1 | Biology of Reproduction | 2007 | 629 |
| 15 | On the Specificity of the Oxygenation of Unsaturated Fatty Acids Catalyzed by Soybean Lipoxidase | Journal of Biological Chemistry | 1967 | 620 |
| 16 | Intermediary metabolism of fructose | American Journal of Clinical Nutrition | 1993 | 574 |
| 17 | ICAM-1 signaling in endothelial cells | Pharmacological Reports | 2009 | 534 |
| 18 | Heat stress and seasonal effects on reproduction in the dairy cow—a review | Theriogenology | 2003 | 530 |
| 19 | Osteoregulatory nature of mechanical stimuli: Function as a determinant for adaptive remodeling in bone | Journal of Orthopaedic Research | 1987 | 466 |
| 20 | Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer | Nature | 2014 | 450 |
| 21 | Classification, nomenclature, and database development for hepatitis C virus (HCV) and related viruses: proposals for standardization | Archives of Virology | 1998 | 427 |
| 22 | Guidelines for the Diagnosis and Treatment of Canine Chronic Valvular Heart Disease | Journal of Veterinary Internal Medicine | 2009 | 423 |
| 23 | Chronic Enteropathies in Dogs: Evaluation of Risk Factors for Negative Outcome | Journal of Veterinary Internal Medicine | 2007 | 411 |
| 24 | Anticoagulant activity of heparin: Separation of high-activity and low-activity heparin species by affinity chromatography on immobilized antithrombin | FEBS Letters | 1976 | 408 |
| 25 | Gene editing restores dystrophin expression in a canine model of Duchenne muscular dystrophy | Science | 2018 | 405 |
| 26 | ACVIM consensus guidelines for the diagnosis and treatment of myxomatous mitral valve disease in dogs | Journal of Veterinary Internal Medicine | 2019 | 392 |
| 27 | Functional strain in bone tissue as an objective, and controlling stimulus for adaptive bone remodelling | Journal of Biomechanics | 1987 | 390 |
| 28 | On the Metabolism of Prostaglandins E1 and E2 in Man | Journal of Biological Chemistry | 1971 | 358 |
| 29 | Cutting Edge: The Foxp3 Target miR-155 Contributes to the Development of Regulatory T Cells | Journal of Immunology | 2009 | 350 |
| 30 | The Effect of Age on Thymic Function | Frontiers in Immunology | 2013 | 349 |
| 31 | Follistatin complexes Myostatin and antagonises Myostatin-mediated inhibition of myogenesis | Developmental Biology | 2004 | 347 |
| 32 | Osteocytes, strain detection, bone modeling and remodeling | Calcified Tissue International | 1993 | 345 |
| 33 | Lack of myostatin results in excessive muscle growth but impaired force generation | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 341 |
| 34 | Mechanical loading: biphasic osteocyte survival and targeting of osteoclasts for bone destruction in rat cortical bone | American Journal of Physiology - Cell Physiology | 2003 | 340 |
| 35 | Noncompetitive excitatory amino acid receptor antagonists | Trends in Pharmacological Sciences | 1990 | 337 |
| 36 | Non-invasive axial loading of mouse tibiae increases cortical bone formation and modifies trabecular organization: A new model to study cortical and cancellous compartments in a single loaded element | Bone | 2005 | 336 |
| 37 | Estrus detection and estrus characteristics in housed and pastured Holstein–Friesian cows | Theriogenology | 2010 | 334 |
| 38 | ACVIM consensus statement: Guidelines for the identification, evaluation, and management of systemic hypertension in dogs and cats | Journal of Veterinary Internal Medicine | 2018 | 323 |
| 39 | Mechanical strain-induced NO production by bone cells: a possible role in adaptive bone (re)modeling? | FASEB Journal | 1995 | 312 |
| 40 | Distinguishable Epidemics of Multidrug-Resistant Salmonella Typhimurium DT104 in Different Hosts | Science | 2013 | 310 |
| 41 | Early strain-related changes in enzyme activity in osteocytes following bone loading in vivo | Journal of Bone and Mineral Research | 1989 | 308 |
| 42 | Uterine diseases in cattle after parturition | Veterinary Journal | 2008 | 304 |
| 43 | Inflammatory Airway Disease of Horses—Revised Consensus Statement | Journal of Veterinary Internal Medicine | 2016 | 293 |
| 44 | The Lancet Countdown: tracking progress on health and climate change | Lancet, The | 2017 | 292 |
| 45 | Re-calculating the cost of coccidiosis in chickens | Veterinary Research | 2020 | 289 |
| 46 | Ovarian follicular cells have innate immune capabilities that modulate their endocrine function | Reproduction | 2007 | 286 |
| 47 | The relationship between uterine pathogen growth density and ovarian function in the postpartum dairy cow | Theriogenology | 2007 | 286 |
| 48 | The Effect of MK-801 on Cortical Spreading Depression in the Penumbral Zone following Focal Ischaemia in the Rat | Journal of Cerebral Blood Flow and Metabolism | 1992 | 285 |
| 49 | Fibre Composition, Enzyme Activity and Concentrations of Metabolites and Electrolytes in Muscles of Standardbred Horses | Acta Veterinaria Scandinavica | 1974 | 280 |
| 50 | A cis-acting regulatory mutation causes premature hair graying and susceptibility to melanoma in the horse | Nature Genetics | 2008 | 271 |
