# | Title | Journal | Year | Citations |
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1 | The Metabolic Syndrome and Cardiovascular Risk | Journal of the American College of Cardiology | 2010 | 2,179 |
2 | Transcatheter Aortic Valve Implantation for the Treatment of Severe Symptomatic Aortic Stenosis in Patients at Very High or Prohibitive Surgical Risk | Journal of the American College of Cardiology | 2010 | 929 |
3 | A Qualitative Systematic Overview of the Measurement Properties of Functional Walk Tests Used in the Cardiorespiratory Domain | Chest | 2001 | 864 |
4 | 2016 Canadian Cardiovascular Society Guidelines for the Management of Dyslipidemia for the Prevention of Cardiovascular Disease in the Adult | Canadian Journal of Cardiology | 2016 | 775 |
5 | Transcatheter Aortic Valve Implantation in Failed Bioprosthetic Surgical Valves | JAMA - Journal of the American Medical Association | 2014 | 762 |
6 | Midthigh Muscle Cross-Sectional Area Is a Better Predictor of Mortality than Body Mass Index in Patients with Chronic Obstructive Pulmonary Disease | American Journal of Respiratory and Critical Care Medicine | 2002 | 730 |
7 | Obesity and Cardiovascular Disease | Arteriosclerosis, Thrombosis, and Vascular Biology | 2006 | 658 |
8 | Reslizumab for Poorly Controlled, Eosinophilic Asthma | American Journal of Respiratory and Critical Care Medicine | 2011 | 649 |
9 | A summary of the new GINA strategy: a roadmap to asthma control | European Respiratory Journal | 2015 | 636 |
10 | Airway remodeling-associated mediators in moderate to severe asthma: Effect of steroids on TGF-β, IL-11, IL-17, and type I and type III collagen expression | Journal of Allergy and Clinical Immunology | 2003 | 586 |
11 | Clinical Diagnosis of Hypersensitivity Pneumonitis | American Journal of Respiratory and Critical Care Medicine | 2003 | 569 |
12 | Calcific aortic stenosis | Nature Reviews Disease Primers | 2016 | 568 |
13 | The endothelin axis: emerging role in cancer | Nature Reviews Cancer | 2003 | 527 |
14 | Prognostic Value of Fractional Flow Reserve | Journal of the American College of Cardiology | 2014 | 513 |
15 | Physical Activity and Cardiorespiratory Fitness as Major Markers of Cardiovascular Risk: Their Independent and Interwoven Importance to Health Status | Progress in Cardiovascular Diseases | 2015 | 511 |
16 | 2017 Comprehensive Update of the Canadian Cardiovascular Society Guidelines for the Management of Heart Failure | Canadian Journal of Cardiology | 2017 | 503 |
17 | Predictive Factors, Management, and Clinical Outcomes of Coronary Obstruction Following Transcatheter Aortic Valve Implantation | Journal of the American College of Cardiology | 2013 | 502 |
18 | Polychemotherapy in advanced non small cell lung cancer: a meta-analysis | Lancet, The | 1993 | 493 |
19 | Cardiovascular and Metabolic Heterogeneity of Obesity | Circulation | 2018 | 493 |
20 | Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes | Nature Genetics | 2017 | 472 |
21 | Tecemotide (L-BLP25) versus placebo after chemoradiotherapy for stage III non-small-cell lung cancer (START): a randomised, double-blind, phase 3 trial | Lancet Oncology, The | 2014 | 446 |
22 | Integrative Molecular Characterization of Malignant Pleural Mesothelioma | Cancer Discovery | 2018 | 422 |
23 | Acute kidney injury following transcatheter aortic valve implantation: predictive factors, prognostic value, and comparison with surgical aortic valve replacement | European Heart Journal | 2010 | 410 |
24 | Tumor Necrosis Factor and Granulocyte Macrophage-Colony Stimulating Factor Stimulate Human Macrophages to Restrict Growth of Virulent Mycobacterium avium and to Kill Avirulent M. avium: Killing Effector Mechanism Depends on the Generation of Reactive Nitrogen Intermediates | Journal of Leukocyte Biology | 1991 | 399 |
25 | Inhibitory effects of an anti-IgE antibody E25 on allergen-induced early asthmatic response. | American Journal of Respiratory and Critical Care Medicine | 1997 | 394 |
26 | Low-Flow, Low-Gradient Aortic Stenosis With Normal and Depressed Left Ventricular Ejection Fraction | Journal of the American College of Cardiology | 2012 | 368 |
27 | Timing, Predictive Factors, and Prognostic Value of Cerebrovascular Events in a Large Cohort of Patients Undergoing Transcatheter Aortic Valve Implantation | Circulation | 2012 | 367 |
28 | Efficacy and tolerability of anti-immunoglobulin E therapy with omalizumab in patients with concomitant allergic asthma and persistent allergic rhinitis: SOLAR | Allergy: European Journal of Allergy and Clinical Immunology | 2004 | 361 |
29 | Evaluation of the ulnopalmar arterial arches with pulse oximetry and plethysmography: Comparison with the Allen's test in 1010 patients | American Heart Journal | 2004 | 349 |
30 | Methods for Sampling of Airborne Viruses | Microbiology and Molecular Biology Reviews | 2008 | 343 |
31 | Socioeconomic status and risk of cardiovascular disease in 20 low-income, middle-income, and high-income countries: the Prospective Urban Rural Epidemiologic (PURE) study | The Lancet Global Health | 2019 | 340 |
32 | Clinical spectrum of bronchogenic cysts of the mediastinum and lung in the adult | Annals of Thoracic Surgery | 1991 | 336 |
33 | Meteorological conditions, climate change, new emerging factors, and asthma and related allergic disorders. A statement of the World Allergy Organization | World Allergy Organization Journal | 2015 | 328 |
34 | Effects of Home-Based Pulmonary Rehabilitation in Patients with Chronic Obstructive Pulmonary Disease | Annals of Internal Medicine | 2008 | 323 |
35 | The Impact of Integration of a Multidetector Computed Tomography Annulus Area Sizing Algorithm on Outcomes of Transcatheter Aortic Valve Replacement | Journal of the American College of Cardiology | 2013 | 322 |
36 | A Randomized Study Comparing Same-Day Home Discharge and Abciximab Bolus Only to Overnight Hospitalization and Abciximab Bolus and Infusion After Transradial Coronary Stent Implantation | Circulation | 2006 | 315 |
37 | Overview of Epidemiology and Contribution of Obesity and Body Fat Distribution to Cardiovascular Disease: An Update | Progress in Cardiovascular Diseases | 2018 | 311 |
38 | Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis | Nature Genetics | 2017 | 306 |
39 | Transcatheter Versus Medical Treatment of Patients With Symptomatic Severe Tricuspid Regurgitation | Journal of the American College of Cardiology | 2019 | 302 |
40 | What is the Relationship between Risky Outdoor Play and Health in Children? A Systematic Review | International Journal of Environmental Research and Public Health | 2015 | 295 |
41 | Tiotropium and olodaterol fixed-dose combinationversusmono-components in COPD (GOLD 2–4) | European Respiratory Journal | 2015 | 294 |
42 | Paradoxical low flow and/or low gradient severe aortic stenosis despite preserved left ventricular ejection fraction: implications for diagnosis and treatment | European Heart Journal | 2010 | 293 |
43 | Precision Nutrition: A Review of Personalized Nutritional Approaches for the Prevention and Management of Metabolic Syndrome | Nutrients | 2017 | 292 |
44 | High Yield of RNA Sequencing for Targetable Kinase Fusions in Lung Adenocarcinomas with No Mitogenic Driver Alteration Detected by DNA Sequencing and Low Tumor Mutation Burden | Clinical Cancer Research | 2019 | 292 |
45 | Improvements in Symptom-Limited Exercise Performance Over 8 h With Once-Daily Tiotropium in Patients With COPD | Chest | 2005 | 291 |
46 | 1-Year Outcomes of Transcatheter Mitral Valve Replacement in Patients With Severe Mitral Annular Calcification | Journal of the American College of Cardiology | 2018 | 288 |
47 | Long-Term Outcomes After Transcatheter Aortic Valve Implantation | Journal of the American College of Cardiology | 2012 | 283 |
48 | GINA 2019: a fundamental change in asthma management | European Respiratory Journal | 2019 | 277 |
49 | Transcatheter aortic valve implantation: current and future approaches | Nature Reviews Cardiology | 2012 | 275 |
50 | Relative Scarcity of Asthma and Atopy among Rural Adolescents Raised on a Farm | American Journal of Respiratory and Critical Care Medicine | 2000 | 274 |