| Systematic determination of genetic network architecture | Nature Genetics | 1999 | 1.9K |
| Genome-wide analysis of DNA copy-number changes using cDNA microarrays | Nature Genetics | 1999 | 712 |
| Myosin-V is a processive actin-based motor | Nature | 1999 | 695 |
| Which Clinical Anesthesia Outcomes Are Important to Avoid? The Perspective of Patients | Anesthesia and Analgesia | 1999 | 642 |
| AneuRx stent graft versus open surgical repair of abdominal aortic aneurysms: multicenter prospective clinical trial | Journal of Vascular Surgery | 1999 | 571 |
| Is protein folding hierarchic? I. Local structure and peptide folding | Trends in Biochemical Sciences | 1999 | 453 |
| Rett syndrome and beyond: recurrent spontaneous and familial MECP2 mutations at CpG hotspots | American Journal of Human Genetics | 1999 | 417 |
| Bone mineral acquisition in healthy Asian, Hispanic, black, and Caucasian youth: a longitudinal study | Journal of Clinical Endocrinology and Metabolism | 1999 | 355 |
| Is protein folding hierarchic? II. Folding intermediates and transition states | Trends in Biochemical Sciences | 1999 | 346 |
| Reciprocal inhibitory connections and network synchrony in the mammalian thalamus | Science | 1999 | 313 |
| MRI abnormalities associated with partial status epilepticus | Neurology | 1999 | 293 |
| Recruitment of a hedgehog regulatory circuit in butterfly eyespot evolution | Science | 1999 | 276 |
| Single-agent monoclonal antibody efficacy in bulky non-Hodgkin's lymphoma: results of a phase II trial of rituximab | Journal of Clinical Oncology | 1999 | 253 |
| Image-guided robotic radiosurgery | Neurosurgery | 1999 | 233 |
| Pelvic arterial embolization for control of obstetric hemorrhage: a five-year experience | American Journal of Obstetrics and Gynecology | 1999 | 230 |
| Multicenter clinical trial of recombinant human insulin-like growth factor I in patients with acute renal failure | Kidney International | 1999 | 229 |
| Which clinical anesthesia outcomes are both common and important to avoid? The perspective of a panel of expert anesthesiologists | Anesthesia and Analgesia | 1999 | 227 |
| Immunosuppressant PG490 (triptolide) inhibits T-cell interleukin-2 expression at the level of purine-box/nuclear factor of activated T-cells and NF-kappaB transcriptional activation | Journal of Biological Chemistry | 1999 | 226 |
| Image-guided Robotic Radiosurgery | Neurosurgery | 1999 | 222 |
| Expanding the window for thrombolytic therapy in acute stroke. The potential role of acute MRI for patient selection | Stroke | 1999 | 219 |
| Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity | Molecular and Cellular Biology | 1999 | 215 |
| Clinical potential of intravascular ultrasound for physiological assessment of coronary stenosis: relationship between quantitative ultrasound tomography and pressure-derived fractional flow reserve | Circulation | 1999 | 212 |
| Which clinical anesthesia outcomes are important to avoid? The perspective of patients | Anesthesia and Analgesia | 1999 | 211 |
| Pulmonary tuberculosis: the essentials | Radiology | 1999 | 201 |
| Which Clinical Anesthesia Outcomes Are Both Common and Important to Avoid? The Perspective of a Panel of Expert Anesthesiologists | Anesthesia and Analgesia | 1999 | 201 |
