| # | Title | Journal | Year | Citations |
|---|
| 1 | Prospective Identification of Tumorigenic Prostate Cancer Stem Cells | Cancer Research | 2005 | 2,564 |
| 2 | Global causes of blindness and distance vision impairment 1990–2020: a systematic review and meta-analysis | The Lancet Global Health | 2017 | 2,053 |
| 3 | American Joint Committee on Cancer prognostic factors consensus conference | The Lancet Global Health | 2000 | 537 |
| 4 | THE MORBIDITY AND MORTALITY OF RIB FRACTURES | Journal of Trauma | 1994 | 512 |
| 5 | Reliability and Validity of a New Five‐level Triage Instrument | Academic Emergency Medicine | 2000 | 461 |
| 6 | Multi-system neurological disease is common in patients with OPA1 mutations | Brain | 2010 | 385 |
| 7 | Impaired functional capacity is associated with all-cause mortality after major elective intra-abdominal surgery | British Journal of Anaesthesia | 2010 | 315 |
| 8 | Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia | Blood | 2013 | 252 |
| 9 | Early Procedural and Health Status Outcomes After Chronic Total Occlusion Angioplasty | JACC: Cardiovascular Interventions | 2017 | 234 |
| 10 | Changing Epidemiology of Acute Appendicitis in the United States: Study Period 1993–2008 | Journal of Surgical Research | 2012 | 232 |
| 11 | Intraoperative Awareness During General Anesthesia for Cesarean Delivery | Anesthesia and Analgesia | 2009 | 231 |
| 12 | Implementation and Refinement of the Emergency Severity Index | Academic Emergency Medicine | 2001 | 211 |
| 13 | Antepartum dalteparin versus no antepartum dalteparin for the prevention of pregnancy complications in pregnant women with thrombophilia (TIPPS): a multinational open-label randomised trial | Lancet, The | 2014 | 210 |
| 14 | Clinical prediction rules | BMJ: British Medical Journal | 2012 | 201 |
| 15 | Prevalence of Fracture and Fragment Embolization of Bard Retrievable Vena Cava Filters and Clinical Implications Including Cardiac Perforation and Tamponade | Archives of Internal Medicine | 2010 | 192 |
| 16 | Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions | Genome Biology | 2008 | 191 |
| 17 | Haematological malignancy: are patients appropriately referred for specialist palliative and hospice care? A systematic review and meta-analysis of published data | Palliative Medicine | 2011 | 191 |
| 18 | Accurate Assessment of Adherence | Chest | 2011 | 179 |
| 19 | Improving Service Quality by Understanding Emergency Department Flow: A White Paper and Position Statement Prepared For the American Academy of Emergency Medicine | Journal of Emergency Medicine | 2010 | 171 |
| 20 | Melatonin Versus Placebo in Children with Autism Spectrum Conditions and Severe Sleep Problems Not Amenable to Behaviour Management Strategies: A Randomised Controlled Crossover Trial | Journal of Autism and Developmental Disorders | 2011 | 164 |
| 21 | British Association of Dermatologists’ guidelines for the management of bullous pemphigoid 2012 | British Journal of Dermatology | 2012 | 160 |
| 22 | Retinal haemorrhages and related findings in abusive and non-abusive head trauma: a systematic review | Eye | 2013 | 156 |
| 23 | Fournier’s Gangrene | Surgical Clinics of North America | 1994 | 152 |
| 24 | American Joint Committee on Cancer Prognostic Factors Consensus Conference | Surgical Clinics of North America | 1999 | 146 |
| 25 | Frequency of low level bacteremia in infants from birth to two months of age | Pediatric Infectious Disease Journal | 1997 | 146 |
| 26 | Earlier recognition of nephrotoxicity using novel biomarkers of acute kidney injury | Clinical Toxicology | 2011 | 142 |
| 27 | Frequency of Low-Level Bacteremia in Children from Birth to Fifteen Years of Age | Journal of Clinical Microbiology | 2000 | 142 |
| 28 | Are there potential problems with generic substitution of antiepileptic drugs? | Seizure: the Journal of the British Epilepsy Association | 2006 | 131 |
| 29 | Orlistat Is as Beneficial as Metformin in the Treatment of Polycystic Ovarian Syndrome | Journal of Clinical Endocrinology and Metabolism | 2005 | 128 |
| 30 | Extent, nature and consequences of adverse events: results of a retrospective casenote review in a large NHS hospital | Quality and Safety in Health Care | 2007 | 128 |
| 31 | Revised national guidelines for analysis of cerebrospinal fluid for bilirubin in suspected subarachnoid haemorrhage | Annals of Clinical Biochemistry | 2008 | 121 |
| 32 | Prediction and prevention of thromboembolic events with enoxaparin in cancer patients with elevated tissue factor‐bearing microparticles: a randomized‐controlled phase II trial (the Microtec study) | British Journal of Haematology | 2013 | 115 |
| 33 | Childbirth and prolapse: long‐term associations with the symptoms and objective measurement of pelvic organ prolapse | BJOG: an International Journal of Obstetrics and Gynaecology | 2013 | 113 |
| 34 | Disopyramide-induced ventricular fibrillation | American Journal of Cardiology | 1979 | 112 |
| 35 | Hashimoto’s encephalopathy | Neurology | 2003 | 112 |
| 36 | Warfarin therapy: evolving strategies in anticoagulation | American Family Physician | 1999 | 112 |
| 37 | Evidence summary: the relationship between oral and cardiovascular disease | British Dental Journal | 2017 | 111 |
| 38 | Targeting protein disulfide isomerase with the flavonoid isoquercetin to improve hypercoagulability in advanced cancer | JCI Insight | 2019 | 110 |
| 39 | Suitability of throat culture procedures for detection of group A streptococci and as reference standards for evaluation of streptococcal antigen detection kits | Journal of Clinical Microbiology | 1990 | 109 |
| 40 | Keratinocyte growth factor induces angiogenesis and protects endothelial barrier function | Journal of Cell Science | 1999 | 108 |
| 41 | Detection of Occult Pneumothoraces on Abdominal Computed Tomographic Scans in Trauma Patients | Arteriosclerosis, Thrombosis, and Vascular Biology | 2000 | 107 |
| 42 | Interventions for adult Eustachian tube dysfunction: asystematic review | Health Technology Assessment | 2014 | 103 |
| 43 | The Opportunity Loss of Boarding Admitted Patients in the Emergency Department | Academic Emergency Medicine | 2007 | 102 |
| 44 | Nail abnormalities: clues to systemic disease | American Family Physician | 2004 | 97 |
| 45 | Predictors for acute and chronic pouchitis following restorative proctocolectomy for ulcerative colitis | Colorectal Disease | 2008 | 96 |
| 46 | Amiodarone: guidelines for use and monitoring | American Family Physician | 2003 | 96 |
| 47 | Thyroid cancer susceptibility polymorphisms: confirmation of loci on chromosomes 9q22 and 14q13, validation of a recessive 8q24 locus and failure to replicate a locus on 5q24 | Journal of Medical Genetics | 2012 | 95 |
| 48 | Predicting Risk of Death in General Surgery Patients on the Basis of Preoperative Variables Using American College of Surgeons National Surgical Quality Improvement Program Data | Journal of Medical Genetics | 2012 | 95 |
| 49 | Use, Cost, Complications, and Mortality of Robotic versus Nonrobotic General Surgery Procedures Based on a Nationwide Database | American Surgeon | 2013 | 94 |
| 50 | Destined to die in hospital? Systematic review and meta-analysis of place of death in haematological malignancy | BMC Palliative Care | 2010 | 93 |
