| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 3 | Atezolizumab versus docetaxel for patients with previously treated non-small-cell lung cancer (POPLAR): a multicentre, open-label, phase 2 randomised controlled trial | Lancet, The | 2016 | 2,390 |
| 4 | Hyperspectral Unmixing Overview: Geometrical, Statistical, and Sparse Regression-Based Approaches | IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing | 2012 | 2,181 |
| 5 | A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease | Alzheimer's and Dementia | 2014 | 1,863 |
| 6 | EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update | Annals of the Rheumatic Diseases | 2020 | 1,860 |
| 7 | Ancient human genomes suggest three ancestral populations for present-day Europeans | Nature | 2014 | 1,179 |
| 8 | The Dalton quantum chemistry program system | Wiley Interdisciplinary Reviews: Computational Molecular Science | 2014 | 1,166 |
| 9 | Gene Expression Classification of Colon Cancer into Molecular Subtypes: Characterization, Validation, and Prognostic Value | PLoS Medicine | 2013 | 1,064 |
| 10 | Reduction of Macrophage Infiltration and Chemoattractant Gene Expression Changes in White Adipose Tissue of Morbidly Obese Subjects After Surgery-Induced Weight Loss | Diabetes | 2005 | 992 |
| 11 | Epidemiology of neonatal encephalopathy and hypoxic–ischaemic encephalopathy | Early Human Development | 2010 | 941 |
| 12 | The I.A.N.A. task force on frailty assessment of older people in clinical practice | Journal of Nutrition, Health and Aging | 2008 | 821 |
| 13 | Comparison of ixekizumab with etanercept or placebo in moderate-to-severe psoriasis (UNCOVER-2 and UNCOVER-3): results from two phase 3 randomised trials | Lancet, The | 2015 | 719 |
| 14 | Reconstructing Native American population history | Nature | 2012 | 699 |
| 15 | Lung Cancer That Harbors an HER2 Mutation: Epidemiologic Characteristics and Therapeutic Perspectives | Journal of Clinical Oncology | 2013 | 572 |
| 16 | Desolvation of Ions in Subnanometer Pores and Its Effect on Capacitance and Double‐Layer Theory | Angewandte Chemie - International Edition | 2008 | 569 |
| 17 | Classification of radical hysterectomy | Lancet Oncology, The | 2008 | 548 |
| 18 | Pitfalls in the measurement of muscle mass: a need for a reference standard | Journal of Cachexia, Sarcopenia and Muscle | 2018 | 482 |
| 19 | Development and validation of the Unified Multiple System Atrophy Rating Scale (UMSARS) | Movement Disorders | 2004 | 481 |
| 20 | Sarcopenia in daily practice: assessment and management | BMC Geriatrics | 2016 | 468 |
| 21 | Arthropod Diversity in a Tropical Forest | Science | 2012 | 445 |
| 22 | The gene encoding adipose triglyceride lipase (PNPLA2) is mutated in neutral lipid storage disease with myopathy | Nature Genetics | 2007 | 415 |
| 23 | Role of oncogenic KRAS in the diagnosis, prognosis and treatment of pancreatic cancer | Nature Reviews Gastroenterology and Hepatology | 2020 | 399 |
| 24 | A prospective phase III, randomized, double‐blind, placebo‐controlled study of brodalumab in patients with moderate‐to‐severe plaque psoriasis | British Journal of Dermatology | 2016 | 378 |
| 25 | Improvement of Glucose Tolerance and Hepatic Insulin Sensitivity by Oligofructose Requires a Functional Glucagon-Like Peptide 1 Receptor | Diabetes | 2006 | 365 |
| 26 | A Human Aware Mobile Robot Motion Planner | Diabetes | 2007 | 365 |
| 27 | Bromodomain inhibitor OTX015 in patients with acute leukaemia: a dose-escalation, phase 1 study | Lancet Haematology,the | 2016 | 359 |
| 28 | Vascular smooth muscle cell death, autophagy and senescence in atherosclerosis | Cardiovascular Research | 2018 | 356 |
| 29 | European S3‐Guidelines on the systemic treatment of psoriasis vulgaris – Update 2015 – Short version – EDF in cooperation with EADV and IPC | Journal of the European Academy of Dermatology and Venereology | 2015 | 353 |
| 30 | Dabrafenib in patients with BRAFV600E-positive advanced non-small-cell lung cancer: a single-arm, multicentre, open-label, phase 2 trial | Lancet Oncology, The | 2016 | 352 |
| 31 | Insulin Storage and Glucose Homeostasis in Mice Null for the Granule Zinc Transporter ZnT8 and Studies of the Type 2 Diabetes–Associated Variants | Diabetes | 2009 | 347 |
| 32 | Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity | Nature Genetics | 2005 | 341 |
| 33 | β-NaMnO2: A High-Performance Cathode for Sodium-Ion Batteries | Journal of the American Chemical Society | 2014 | 333 |
| 34 | Whole-genome sequencing in health care | European Journal of Human Genetics | 2013 | 330 |
| 35 | Adipocyte Lipases and Defect of Lipolysis in Human Obesity | Diabetes | 2005 | 329 |
| 36 | Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation | Cell | 2016 | 317 |
| 37 | Kinematic Control of Redundant Manipulators: Generalizing the Task-Priority Framework to Inequality Task | IEEE Transactions on Robotics | 2011 | 314 |
| 38 | Lost in thoughts: Neural markers of low alertness during mind wandering | NeuroImage | 2011 | 313 |
| 39 | Prospective evaluation of gene mutations and minimal residual disease in patients with core binding factor acute myeloid leukemia | Blood | 2013 | 313 |
| 40 | Quality of Life in Sarcopenia and Frailty | Calcified Tissue International | 2013 | 310 |
| 41 | Joint Bayesian Endmember Extraction and Linear Unmixing for Hyperspectral Imagery | IEEE Transactions on Signal Processing | 2009 | 299 |
| 42 | In situ NMR and electrochemical quartz crystal microbalance techniques reveal the structure of the electrical double layer in supercapacitors | Nature Materials | 2015 | 296 |
| 43 | Assessment of Muscle Function and Physical Performance in Daily Clinical Practice | Calcified Tissue International | 2019 | 295 |
| 44 | One Shot Laser Pulse Induced Reversible Spin Transition in the Spin-Crossover Complex [Fe(C4H4N2){Pt(CN)4}] at Room Temperature | Angewandte Chemie - International Edition | 2005 | 294 |
| 45 | Nanoreactors based on (polymerized) ABA-triblock copolymer vesicles | Chemical Communications | 2000 | 284 |
| 46 | Involvement of tissue bacteria in the onset of diabetes in humans: evidence for a concept | Diabetologia | 2011 | 283 |
| 47 | Oxidized low-density lipoprotein-induced apoptosis | Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids | 2002 | 282 |
| 48 | Does nutrition play a role in the prevention and management of sarcopenia? | Clinical Nutrition | 2018 | 279 |
| 49 | The antiperinuclear factor and the so-called antikeratin antibodies are the same rheumatoid arthritis-specific autoantibodies. | Journal of Clinical Investigation | 1995 | 277 |
| 50 | Combining Strong and Weak Gravitational Lensing in Abell 1689 | Astrophysical Journal | 2007 | 266 |
