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Top Articles

#TitleJournalYearCitations
1Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Women's Health Initiative Randomized Controlled TrialJAMA - Journal of the American Medical Association200214,536
2Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013Lancet, The20149,122
3Prediction of Coronary Heart Disease Using Risk Factor CategoriesCirculation19988,099
4A simple efficient liquid scintillator for counting aqueous solutions in a liquid scintillation counterAnalytical Biochemistry19607,552
5CHARMM: The biomolecular simulation programJournal of Computational Chemistry20097,077
62014 Evidence-Based Guideline for the Management of High Blood Pressure in AdultsJAMA - Journal of the American Medical Association20146,625
7High-Resolution Profiling of Histone Methylations in the Human GenomeCell20076,036
8Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)Autophagy20164,701
9Genetic studies of body mass index yield new insights for obesity biologyNature20153,823
10The Patient-Reported Outcomes Measurement Information System (PROMIS) developed and tested its first wave of adult self-reported health outcome item banks: 2005–2008Journal of Clinical Epidemiology20103,521
11Circulating Endothelial Progenitor Cells, Vascular Function, and Cardiovascular RiskNew England Journal of Medicine20033,249
12Quantitative Insulin Sensitivity Check Index: A Simple, Accurate Method for Assessing Insulin Sensitivity In HumansJournal of Clinical Endocrinology and Metabolism20003,201
13Guidelines for the use and interpretation of assays for monitoring autophagyAutophagy20123,122
14Multi-Ethnic Study of Atherosclerosis: Objectives and DesignAmerican Journal of Epidemiology20023,068
15Survival in Patients with Primary Pulmonary HypertensionAnnals of Internal Medicine19913,050
16Protein Oxidation in Aging, Disease, and Oxidative StressJournal of Biological Chemistry19972,859
17Comparison of global estimates of prevalence and risk factors for peripheral artery disease in 2000 and 2010: a systematic review and analysisLancet, The20132,640
18Association analyses of 249,796 individuals reveal 18 new loci associated with body mass indexNature Genetics20102,634
19Protein oxidation and agingScience19922,526
20Requirement for Generation of H(2)O(2) for Platelet-Derived Growth Factor Signal Tran sductionScience19952,463
21The cardiovascular health study: Design and rationaleAnnals of Epidemiology19912,407
22Abnormal Endothelium-Dependent Vascular Relaxation in Patients with Essential HypertensionNew England Journal of Medicine19902,224
23[37] Carbonyl assays for determination of oxidatively modified proteinsMethods in Enzymology19942,211
24Value of the Ventilation/Perfusion Scan in Acute Pulmonary EmbolismJAMA - Journal of the American Medical Association19902,204
25The nitrate–nitrite–nitric oxide pathway in physiology and therapeuticsNature Reviews Drug Discovery20082,084
26Combinatorial patterns of histone acetylations and methylations in the human genomeNature Genetics20082,034
27Single-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopyNature Methods20082,008
28Removal of Fatty Acids from Serum Albumin by Charcoal TreatmentJournal of Biological Chemistry19671,990
29Effect of coronary artery bypass graft surgery on survival: overview of 10-year results from randomised trials by the Coronary Artery Bypass Graft Surgery Trialists CollaborationLancet, The19941,919
30Cardiovascular disease risk profilesAmerican Heart Journal19911,900
31Signal transduction by reactive oxygen speciesJournal of Cell Biology20111,878
32Identification and proteomic profiling of exosomes in human urineProceedings of the National Academy of Sciences of the United States of America20041,875
33Transfusion of Plasma, Platelets, and Red Blood Cells in a 1:1:1 vs a 1:1:2 Ratio and Mortality in Patients With Severe TraumaJAMA - Journal of the American Medical Association20151,874
34IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathwaysNature Immunology20071,873
35Tyrosine HydroxylaseJournal of Biological Chemistry19641,867
36Defining the role of common variation in the genomic and biological architecture of adult human heightNature Genetics20141,818
37CHARMM-GUIMembrane Buildertoward realistic biological membrane simulationsJournal of Computational Chemistry20141,802
38Hundreds of variants clustered in genomic loci and biological pathways affect human heightNature20101,789
39Direct Measurement of Distances and Angles in Biomolecules by NMR in a Dilute Liquid Crystalline MediumScience19971,705
40The effectiveness of interventions to increase physical activityA systematic review1 and 2American Journal of Preventive Medicine20021,698
41Functional MRI evidence for adult motor cortex plasticity during motor skill learningNature19951,642
42Free radical-mediated oxidation of free amino acids and amino acid residues in proteinsAmino Acids20031,637
43Non-muscle myosin II takes centre stage in cell adhesion and migrationNature Reviews Molecular Cell Biology20091,634
44JAKS AND STATS: Biological ImplicationsAnnual Review of Immunology19981,624
45Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulationNature Medicine20031,606
46Lattice light-sheet microscopy: Imaging molecules to embryos at high spatiotemporal resolutionScience20141,567
47OpenMM 7: Rapid development of high performance algorithms for molecular dynamicsPLoS Computational Biology20171,561
48Mitogenic Signaling Mediated by Oxidants in Ras-Transformed FibroblastsScience19971,505
49Global Burden of Hypertension and Systolic Blood Pressure of at Least 110 to 115 mm Hg, 1990-2015JAMA - Journal of the American Medical Association20171,492
50High-Density Lipoprotein — The Clinical Implications of Recent StudiesNew England Journal of Medicine19891,459