| # | Title | Journal | Year | Citations |
|---|
| 1 | SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness | Nature | 2020 | 1,153 |
| 2 | Safety and immunogenicity of SARS-CoV-2 variant mRNA vaccine boosters in healthy adults: an interim analysis | Nature Medicine | 2021 | 361 |
| 3 | Immune correlates of protection by mRNA-1273 vaccine against SARS-CoV-2 in nonhuman primates | Science | 2021 | 244 |
| 4 | mRNA vaccine–induced neoantigen-specific T cell immunity in patients with gastrointestinal cancer | Journal of Clinical Investigation | 2020 | 218 |
| 5 | Prospects for a safe COVID-19 vaccine | Science Translational Medicine | 2020 | 204 |
| 6 | Impact of mRNA chemistry and manufacturing process on innate immune activation | Science Advances | 2020 | 195 |
| 7 | Effectiveness of mRNA-1273 against delta, mu, and other emerging variants of SARS-CoV-2: test negative case-control study | BMJ, The | 2021 | 180 |
| 8 | mRNA-1273 or mRNA-Omicron boost in vaccinated macaques elicits similar B cell expansion, neutralizing responses, and protection from Omicron | Cell | 2022 | 179 |
| 9 | Durable anticancer immunity from intratumoral administration of IL-23, IL-36γ, and OX40L mRNAs | Science Translational Medicine | 2019 | 176 |
| 10 | Systemic mRNA Therapy for the Treatment of Fabry Disease: Preclinical Studies in Wild-Type Mice, Fabry Mouse Model, and Wild-Type Non-human Primates | American Journal of Human Genetics | 2019 | 102 |
| 11 | Intratumoral IL12 mRNA Therapy Promotes TH1 Transformation of the Tumor Microenvironment | Clinical Cancer Research | 2020 | 102 |
| 12 | Omicron variant Spike-specific antibody binding and Fc activity are preserved in recipients of mRNA or inactivated COVID-19 vaccines | Science Translational Medicine | 2022 | 84 |
| 13 | Protection against SARS-CoV-2 Beta variant in mRNA-1273 vaccine–boosted nonhuman primates | Science | 2021 | 83 |
| 14 | A multiclade env–gag VLP mRNA vaccine elicits tier-2 HIV-1-neutralizing antibodies and reduces the risk of heterologous SHIV infection in macaques | Nature Medicine | 2021 | 80 |
| 15 | Broadly neutralizing antibodies target a haemagglutinin anchor epitope | Nature | 2022 | 78 |
| 16 | mRNA-1273 vaccine-induced antibodies maintain Fc effector functions across SARS-CoV-2 variants of concern | Immunity | 2022 | 76 |
| 17 | Dual mRNA therapy restores metabolic function in long-term studies in mice with propionic acidemia | Nature Communications | 2020 | 70 |
| 18 | Protection from SARS-CoV-2 Delta one year after mRNA-1273 vaccination in rhesus macaques coincides with anamnestic antibody response in the lung | Cell | 2022 | 64 |
| 19 | Protective activity of mRNA vaccines against ancestral and variant SARS-CoV-2 strains | Science Translational Medicine | 2022 | 55 |
| 20 | Real-world effectiveness of the mRNA-1273 vaccine against COVID-19: Interim results from a prospective observational cohort study | The Lancet Regional Health Americas | 2022 | 54 |
| 21 | Oligonucleotide Sequence Mapping of Large Therapeutic mRNAs via Parallel Ribonuclease Digestions and LC-MS/MS | Analytical Chemistry | 2019 | 43 |
| 22 | Synthetic human ABCB4 mRNA therapy rescues severe liver disease phenotype in a BALB/c.Abcb4 mouse model of PFIC3 | Journal of Hepatology | 2021 | 34 |
| 23 | SARS-CoV-2 vaccines elicit durable immune responses in infant rhesus macaques | Science Immunology | 2021 | 34 |
| 24 | Systemic modified messenger RNA for replacement therapy in alpha 1-antitrypsin deficiency | Scientific Reports | 2020 | 31 |
| 25 | VEGFA mRNA for regenerative treatment of heart failure | Nature Reviews Drug Discovery | 2022 | 31 |
| 26 | Review of Current Vaccine Development Strategies to Prevent Coronavirus Disease 2019 (COVID-19) | Toxicologic Pathology | 2020 | 29 |
| 27 | Detection and Management of Amyloid-Related Imaging Abnormalities in Patients with Alzheimer’s Disease Treated with Anti-Amyloid Beta Therapy | journal of prevention of Alzheimer's disease, The | 2022 | 25 |
| 28 | Attenuated activation of pulmonary immune cells in mRNA-1273–vaccinated hamsters after SARS-CoV-2 infection | Journal of Clinical Investigation | 2021 | 23 |
| 29 | Chimeric Fusion (F) and Attachment (G) Glycoprotein Antigen Delivery by mRNA as a Candidate Nipah Vaccine | Frontiers in Immunology | 2021 | 21 |
| 30 | Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors | Immunity | 2022 | 21 |
| 31 | Isolation and Antibacterial Activity of Indole Alkaloids from Pseudomonas aeruginosa UWI-1 | Molecules | 2020 | 19 |
| 32 | Vaccinating Adolescents and Children Significantly Reduces COVID-19 Morbidity and Mortality across All Ages: A Population-Based Modeling Study Using the UK as an Example | Vaccines | 2021 | 18 |
| 33 | Comparing antibody assays as correlates of protection against COVID-19 in the COVE mRNA-1273 vaccine efficacy trial | Science Translational Medicine | 2023 | 14 |
| 34 | Tetravalent Immunogen Assembled from Conserved Regions of HIV-1 and Delivered as mRNA Demonstrates Potent Preclinical T-Cell Immunogenicity and Breadth | Vaccines | 2020 | 12 |
| 35 | Novel mRNA therapy restores GALT protein and enzyme activity in a zebrafish model of classic galactosemia | Journal of Inherited Metabolic Disease | 2022 | 10 |
| 36 | Distinct sensitivities to SARS-CoV-2 variants in vaccinated humans and mice | Cell Reports | 2022 | 10 |
| 37 | Recombinant porphobilinogen deaminase targeted to the liver corrects enzymopenia in a mouse model of acute intermittent porphyria | Science Translational Medicine | 2022 | 9 |
| 38 | Intermittent lipid nanoparticle mRNA administration prevents cortical dysmyelination associated with arginase deficiency | Molecular Therapy - Nucleic Acids | 2022 | 9 |
| 39 | AS03-adjuvanted H7N9 inactivated split virion vaccines induce cross-reactive and protective responses in ferrets | Npj Vaccines | 2021 | 8 |
| 40 | Hepatocyte Nuclear Factor 4 alpha 2 Messenger RNA Reprograms Liver‐Enriched Transcription Factors and Functional Proteins in End‐Stage Cirrhotic Human Hepatocytes | Hepatology Communications | 2021 | 7 |
| 41 | mRNA-based therapy in a rabbit model of variegate porphyria offers new insights into the pathogenesis of acute attacks | Molecular Therapy - Nucleic Acids | 2021 | 7 |
| 42 | Abstract 5017: MEDI1191, a novel IL-12 mRNA therapy for intratumoral injection to promote TH1 transformation of the patient tumor microenvironment | Cancer Research | 2019 | 7 |
| 43 | Immunogenicity and protective efficacy of RSV G central conserved domain vaccine with a prefusion nanoparticle | Npj Vaccines | 2022 | 6 |
| 44 | The antibody landscapes following AS03 and MF59 adjuvanted H5N1 vaccination | Npj Vaccines | 2022 | 6 |
| 45 | Innovative vaccine approaches—a Keystone Symposia report | Annals of the New York Academy of Sciences | 2022 | 5 |
| 46 | Messenger RNA as a personalized therapy: The moment of truth for rare metabolic diseases | International Review of Cell and Molecular Biology | 2022 | 5 |
| 47 | Effect of Mailing Educational Material to Patients With Atrial Fibrillation and Their Clinicians on Use of Oral Anticoagulants | JAMA Network Open | 2022 | 4 |
| 48 | Recent Insights into the Pathogenesis of Acute Porphyria Attacks and Increasing Hepatic PBGD as an Etiological Treatment | Life | 2022 | 3 |
| 49 | Abstract 6539: Bioinformatics algorithm of mRNA-4157 identifies neoantigens with pre-existing TIL reactivities in colorectal tumors | | 2020 | 2 |
| 50 | Clinical Development of mRNA Vaccines: Challenges and Opportunities | Current Topics in Microbiology and Immunology | 2022 | 2 |
