| Proposal for a revised definition of dilated cardiomyopathy, hypokinetic non-dilated cardiomyopathy, and its implications for clinical practice: a position statement of the ESC working group on myocardial and pericardial diseases | European Heart Journal | 2016 | 473 |
| Bacteriome and Mycobiome Interactions Underscore Microbial Dysbiosis in Familial Crohn's Disease | MBio | 2016 | 218 |
| A phase 1 clinical trial of the selective BTK inhibitor ONO/GS-4059 in relapsed and refractory mature B-cell malignancies | Blood | 2016 | 195 |
| A novel Alzheimer disease locus located near the gene encoding tau protein | Molecular Psychiatry | 2016 | 175 |
| Next-Generation Sequencing in Diffuse Large B-Cell Lymphoma Highlights Molecular Divergence and Therapeutic Opportunities: a LYSA Study | Clinical Cancer Research | 2016 | 143 |
| Subcutaneous Ustekinumab Provides Clinical Benefit for Two-Thirds of Patients With Crohn's Disease Refractory to Anti-Tumor Necrosis Factor Agents | Clinical Gastroenterology and Hepatology | 2016 | 135 |
| Bullous pemphigoid and dipeptidyl peptidase IV inhibitors: a case-noncase study in the French Pharmacovigilance Database | British Journal of Dermatology | 2016 | 107 |
| Rheumatoid Factor and Disease Activity Are Independent Predictors of Lymphoma in Primary Sjögren's Syndrome | Arthritis and Rheumatology | 2016 | 106 |
| Systemic inflammatory and autoimmune manifestations associated with myelodysplastic syndromes and chronic myelomonocytic leukaemia: a French multicentre retrospective study | Rheumatology | 2016 | 103 |
| Obesity Impairs the Action of the Neuroendocrine Ghrelin System | Trends in Endocrinology and Metabolism | 2016 | 83 |
| Truncating Mutations in the Adhesion G Protein-Coupled Receptor G2 Gene ADGRG2 Cause an X-Linked Congenital Bilateral Absence of Vas Deferens | American Journal of Human Genetics | 2016 | 83 |
| Fistula Plug in Fistulising Ano-Perineal Crohn's Disease: a Randomised Controlled Trial | Journal of Crohn's and Colitis | 2016 | 70 |
| Whole exome sequencing of relapsed/refractory patients expands the repertoire of somatic mutations in diffuse large B-cell lymphoma | Genes Chromosomes and Cancer | 2016 | 62 |
| Influence of the surface charge of PLGA nanoparticles on their in vitro genotoxicity, cytotoxicity, ROS production and endocytosis | Journal of Applied Toxicology | 2016 | 57 |
| Congenital secretory diarrhoea caused by activating germline mutations in GUCY2C | Gut | 2016 | 56 |
| Matching for the nonconventional MHC-I MICA gene significantly reduces the incidence of acute and chronic GVHD | Blood | 2016 | 49 |
| Apolipoprotein E (APOE) ε4 and episodic memory decline in Alzheimer's disease: A review | Ageing Research Reviews | 2016 | 49 |
| Orolingual Angioedema During or After Thrombolysis for Cerebral Ischemia | Stroke | 2016 | 46 |
| Neuroimaging in vascular cognitive impairment: a state-of-the-art review | BMC Medicine | 2016 | 45 |
| Age at disease onset and peak ammonium level rather than interventional variables predict the neurological outcome in urea cycle disorders | Journal of Inherited Metabolic Disease | 2016 | 42 |
| Correlates of dietary energy misreporting among European adolescents: the Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA) study | British Journal of Nutrition | 2016 | 41 |
| In vitro short-term exposure to air pollution PM2.5-0.3 induced cell cycle alterations and genetic instability in a human lung cell coculture model | Environmental Research | 2016 | 41 |
| Mitochondrial oxidative phosphorylation controls cancer cell's life and death decisions upon exposure to MAPK inhibitors | Oncotarget | 2016 | 41 |
| Disruption of a miR-29 binding site leading to COL4A1 upregulation causes pontine autosomal dominant microangiopathy with leukoencephalopathy | Annals of Neurology | 2016 | 40 |
| Hidradenitis suppurativa (HS): An unrecognized paradoxical effect of biologic agents (BA) used in chronic inflammatory diseases | Journal of the American Academy of Dermatology | 2016 | 38 |
