Variation in FTO contributes to childhood obesity and severe adult obesity | Nature Genetics | 2007 | 1.2K |
PPARgamma activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties | Cell Metabolism | 2007 | 918 |
Plasma cells from multiple myeloma patients express B7-H1 (PD-L1) and increase expression after stimulation with IFN-{gamma} and TLR ligands via a MyD88-, TRAF6-, and MEK-dependent pathway | Blood | 2007 | 482 |
The Lille model: a new tool for therapeutic strategy in patients with severe alcoholic hepatitis treated with steroids | Hepatology | 2007 | 441 |
Pseudomonas aeruginosa: resistance and therapeutic options at the turn of the new millennium | Clinical Microbiology and Infection | 2007 | 371 |
Improving physical activity assessment in prepubertal children with high-frequency accelerometry monitoring: a methodological issue | Preventive Medicine | 2007 | 244 |
Safety issues and prospects for future generations of PPAR modulators | Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids | 2007 | 222 |
Activation of invariant NKT cells by toll-like receptor 9-stimulated dendritic cells requires type I interferon and charged glycosphingolipids | Immunity | 2007 | 220 |
Structure of the membrane protein FhaC: a member of the Omp85-TpsB transporter superfamily | Science | 2007 | 213 |
High efficacy and safety profile of fractionated doses of Mylotarg as induction therapy in patients with relapsed acute myeloblastic leukemia: a prospective study of the alfa group | Leukemia | 2007 | 207 |
E-cadherin homophilic ligation inhibits cell growth and epidermal growth factor receptor signaling independently of other cell interactions | Molecular Biology of the Cell | 2007 | 179 |
The neutralizing activity of anti-hepatitis C virus antibodies is modulated by specific glycans on the E2 envelope protein | Journal of Virology | 2007 | 169 |
International labor and capital flows: Complements or substitutes? | Economics Letters | 2007 | 161 |
Alkalizing drugs induce accumulation of amyloid precursor protein by-products in luminal vesicles of multivesicular bodies | Journal of Biological Chemistry | 2007 | 146 |
PPAR agonists: multimodal drugs for the treatment of type-2 diabetes | Best Practice and Research in Clinical Endocrinology and Metabolism | 2007 | 132 |
Bile acid sequestrants and the treatment of type 2 diabetes mellitus | Drugs | 2007 | 130 |
Drug Insight: mechanisms of action and therapeutic applications for agonists of peroxisome proliferator-activated receptors | Nature Clinical Practice Endocrinology and Metabolism | 2007 | 119 |
Pulmonary arterial hypertension: a rare complication of primary Sjögren syndrome: report of 9 new cases and review of the literature | Medicine (United States) | 2007 | 118 |
FXR: a promising target for the metabolic syndrome? | Trends in Pharmacological Sciences | 2007 | 117 |
Functions, dysfunctions and possible therapeutic relevance of adenosine A2A receptors in Huntington's disease | Progress in Neurobiology | 2007 | 94 |
Automatic segmentation of pelvic structures from magnetic resonance images for prostate cancer radiotherapy | International Journal of Radiation Oncology Biology Physics | 2007 | 93 |
Galectin-3 modulates immune and inflammatory responses during helminthic infection: impact of galectin-3 deficiency on the functions of dendritic cells | Infection and Immunity | 2007 | 93 |
Treatment of severe von Willebrand disease with a high-purity von Willebrand factor concentrate (Wilfactin): a prospective study of 50 patients | Journal of Thrombosis and Haemostasis | 2007 | 90 |
Comparison between 308-nm monochromatic excimer light and narrowband UVB phototherapy (311-313 nm) in the treatment of vitiligo--a multicentre controlled study | Journal of the European Academy of Dermatology and Venereology | 2007 | 88 |
Silencing of OB-RGRP in mouse hypothalamic arcuate nucleus increases leptin receptor signaling and prevents diet-induced obesity | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 78 |