Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease | Nature Genetics | 2013 | 2.7K |
Genetic studies of body mass index yield new insights for obesity biology | Nature | 2015 | 2.7K |
Defining the role of common variation in the genomic and biological architecture of adult human height | Nature Genetics | 2014 | 1.3K |
Crowdfunding: Tapping the right crowd | Journal of Business Venturing | 2014 | 1.2K |
Variation in FTO contributes to childhood obesity and severe adult obesity | Nature Genetics | 2007 | 1.2K |
PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway | Nature Medicine | 2001 | 956 |
New genetic loci link adipose and insulin biology to body fat distribution | Nature | 2015 | 920 |
PPARgamma activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties | Cell Metabolism | 2007 | 918 |
The genome of the blood fluke Schistosoma mansoni | Nature | 2009 | 822 |
Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease | Journal of Hepatology | 2015 | 667 |
Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis | Journal of Clinical Investigation | 2006 | 655 |
Adipose tissue in obesity-related inflammation and insulin resistance: cells, cytokines, and chemokines | ISRN Inflammation | 2013 | 587 |
The physiology and clinical utility of anti-Mullerian hormone in women | Human Reproduction Update | 2014 | 513 |
Insights into the evolution of Yersinia pestis through whole-genome comparison with Yersinia pseudotuberculosis | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 513 |
Neuroplasticity - exercise-induced response of peripheral brain-derived neurotrophic factor: a systematic review of experimental studies in human subjects | Sports Medicine | 2010 | 503 |
Plasma cells from multiple myeloma patients express B7-H1 (PD-L1) and increase expression after stimulation with IFN-{gamma} and TLR ligands via a MyD88-, TRAF6-, and MEK-dependent pathway | Blood | 2007 | 482 |
Proposal for a revised definition of dilated cardiomyopathy, hypokinetic non-dilated cardiomyopathy, and its implications for clinical practice: a position statement of the ESC working group on myocardial and pericardial diseases | European Heart Journal | 2016 | 473 |
Phase II trial of weekly paclitaxel for unresectable angiosarcoma: the ANGIOTAX Study | Journal of Clinical Oncology | 2008 | 469 |
Bariatric Surgery Reduces Features of Nonalcoholic Steatohepatitis in Morbidly Obese Patients | Gastroenterology | 2015 | 450 |
The Lille model: a new tool for therapeutic strategy in patients with severe alcoholic hepatitis treated with steroids | Hepatology | 2007 | 441 |
The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice | Journal of Biological Chemistry | 2006 | 396 |
Dabrafenib plus trametinib in patients with BRAF-mutant melanoma brain metastases (COMBI-MB): a multicentre, multicohort, open-label, phase 2 trial | Lancet Oncology, The | 2017 | 389 |
Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children | PLoS Medicine | 2011 | 379 |
Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease | Nature Genetics | 2009 | 374 |
Pseudomonas aeruginosa: resistance and therapeutic options at the turn of the new millennium | Clinical Microbiology and Infection | 2007 | 371 |